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The economic principles of industrial synthetic biology: cosmogony, metabolism and commodities

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The economic principles of industrial synthetic biology: cosmogony, metabolism and commodities. / Mackenzie, Adrian.
In: Engineering Studies, Vol. 5, No. 1, 01.06.2013, p. 74-89.

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Mackenzie A. The economic principles of industrial synthetic biology: cosmogony, metabolism and commodities. Engineering Studies. 2013 Jun 1;5(1):74-89. doi: 10.1080/19378629.2013.764880

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@article{443c02736e954320913f056f1681e205,
title = "The economic principles of industrial synthetic biology: cosmogony, metabolism and commodities",
abstract = "Synthetic biology has been presented as the application of engineering principles to (genomic) biology. But in industrial synthetic biology, alongside the much discussed engineering principles of abstraction, modularity, de-coupling and standardisation, we see many other practices of contextualisation through which engineering projects accrue credibility and realisability. This paper discusses how synthetic biologists working on next-generation biofuels construct an economic calculus for biological forms. As they modify microbes to make fuel from plants, waste gases and sunlight, or introduce new metabolic pathways into organisms, they also create novel stories that link economic and metabolic processes, and they attach new contexts to synthetic biology in various forms ranging from global climate change, peak oil, food security, US foreign policy, through to fashion and diet. Examples drawn from well-known next-generation biofuels companies such as Joule Unlimited, Amyris Technologies, Synthetic Genomics, Solazyme and Aurora Algae illustrate how principles of cosmogonic dreaming, metabolic equivalence and supply chain disruption strain to connect the origins of life on earth, the flux of solar radiation, the optimal metabolic flux in a microbe and the prices of petroleum, palm oil or sugar. This economic calculus both connects engineering practice to a plurality of life forms, and creates a space in which synthetic biology can appear as unprecedented.",
keywords = "synthetic biology, economic calculus, industry, principles, biofuels",
author = "Adrian Mackenzie",
year = "2013",
month = jun,
day = "1",
doi = "10.1080/19378629.2013.764880",
language = "English",
volume = "5",
pages = "74--89",
journal = "Engineering Studies",
issn = "1940-8374",
publisher = "Taylor and Francis Ltd.",
number = "1",

}

RIS

TY - JOUR

T1 - The economic principles of industrial synthetic biology

T2 - cosmogony, metabolism and commodities

AU - Mackenzie, Adrian

PY - 2013/6/1

Y1 - 2013/6/1

N2 - Synthetic biology has been presented as the application of engineering principles to (genomic) biology. But in industrial synthetic biology, alongside the much discussed engineering principles of abstraction, modularity, de-coupling and standardisation, we see many other practices of contextualisation through which engineering projects accrue credibility and realisability. This paper discusses how synthetic biologists working on next-generation biofuels construct an economic calculus for biological forms. As they modify microbes to make fuel from plants, waste gases and sunlight, or introduce new metabolic pathways into organisms, they also create novel stories that link economic and metabolic processes, and they attach new contexts to synthetic biology in various forms ranging from global climate change, peak oil, food security, US foreign policy, through to fashion and diet. Examples drawn from well-known next-generation biofuels companies such as Joule Unlimited, Amyris Technologies, Synthetic Genomics, Solazyme and Aurora Algae illustrate how principles of cosmogonic dreaming, metabolic equivalence and supply chain disruption strain to connect the origins of life on earth, the flux of solar radiation, the optimal metabolic flux in a microbe and the prices of petroleum, palm oil or sugar. This economic calculus both connects engineering practice to a plurality of life forms, and creates a space in which synthetic biology can appear as unprecedented.

AB - Synthetic biology has been presented as the application of engineering principles to (genomic) biology. But in industrial synthetic biology, alongside the much discussed engineering principles of abstraction, modularity, de-coupling and standardisation, we see many other practices of contextualisation through which engineering projects accrue credibility and realisability. This paper discusses how synthetic biologists working on next-generation biofuels construct an economic calculus for biological forms. As they modify microbes to make fuel from plants, waste gases and sunlight, or introduce new metabolic pathways into organisms, they also create novel stories that link economic and metabolic processes, and they attach new contexts to synthetic biology in various forms ranging from global climate change, peak oil, food security, US foreign policy, through to fashion and diet. Examples drawn from well-known next-generation biofuels companies such as Joule Unlimited, Amyris Technologies, Synthetic Genomics, Solazyme and Aurora Algae illustrate how principles of cosmogonic dreaming, metabolic equivalence and supply chain disruption strain to connect the origins of life on earth, the flux of solar radiation, the optimal metabolic flux in a microbe and the prices of petroleum, palm oil or sugar. This economic calculus both connects engineering practice to a plurality of life forms, and creates a space in which synthetic biology can appear as unprecedented.

KW - synthetic biology

KW - economic calculus

KW - industry

KW - principles

KW - biofuels

U2 - 10.1080/19378629.2013.764880

DO - 10.1080/19378629.2013.764880

M3 - Journal article

VL - 5

SP - 74

EP - 89

JO - Engineering Studies

JF - Engineering Studies

SN - 1940-8374

IS - 1

ER -