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The flagellar pocket of trypanosomatids: a critical feature for cell morphogenesis and pathogenicity

Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNChapter (peer-reviewed)

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The flagellar pocket of trypanosomatids : a critical feature for cell morphogenesis and pathogenicity. / McKean, Paul; Gull, Keith.

Structures and organelles in pathogenic protists. ed. / Wanderley de Souza. Berlin : Springer Verlag, 2010. p. 87-113 (Microbiology Monographs; Vol. 17).

Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNChapter (peer-reviewed)

Harvard

McKean, P & Gull, K 2010, The flagellar pocket of trypanosomatids: a critical feature for cell morphogenesis and pathogenicity. in W de Souza (ed.), Structures and organelles in pathogenic protists. Microbiology Monographs, vol. 17, Springer Verlag, Berlin, pp. 87-113. https://doi.org/10.1007/978-3-642-12863-9_4

APA

McKean, P., & Gull, K. (2010). The flagellar pocket of trypanosomatids: a critical feature for cell morphogenesis and pathogenicity. In W. de Souza (Ed.), Structures and organelles in pathogenic protists (pp. 87-113). (Microbiology Monographs; Vol. 17). Springer Verlag. https://doi.org/10.1007/978-3-642-12863-9_4

Vancouver

McKean P, Gull K. The flagellar pocket of trypanosomatids: a critical feature for cell morphogenesis and pathogenicity. In de Souza W, editor, Structures and organelles in pathogenic protists. Berlin: Springer Verlag. 2010. p. 87-113. (Microbiology Monographs). https://doi.org/10.1007/978-3-642-12863-9_4

Author

McKean, Paul ; Gull, Keith. / The flagellar pocket of trypanosomatids : a critical feature for cell morphogenesis and pathogenicity. Structures and organelles in pathogenic protists. editor / Wanderley de Souza. Berlin : Springer Verlag, 2010. pp. 87-113 (Microbiology Monographs).

Bibtex

@inbook{26a2a46074fd478497ac2858cd63196a,
title = "The flagellar pocket of trypanosomatids: a critical feature for cell morphogenesis and pathogenicity",
abstract = "Trypanosomatids possess a highly ordered array of sub-pellicular microtubules that restrict all vesicular traffic to the flagellar pocket (FP); a small invagination of the plasma membrane located at the base of the flagellum. Although the FP is not an adaptation to parasitism per se, it is without question a key pathogenicity feature that has enabled parasitic trypanosomatid species to exploit a diversity of host environments. In this chapter, we focus on the FP of the African trypanosome Trypanosoma brucei and consider recent advances in our understanding of the physical architecture of the FP and the dynamics of FP operation. We conclude with a brief discussion that the trypanosomatid FP represents an example of “extreme biology”, i.e. a normal but exaggerated example of the cell biology present at the flagellum base in proliferating flagellated eukaryotic cells.",
keywords = "Trypanosome , Flagellar Pocket",
author = "Paul McKean and Keith Gull",
year = "2010",
doi = "10.1007/978-3-642-12863-9_4",
language = "English",
isbn = "9783642128622",
series = "Microbiology Monographs",
publisher = "Springer Verlag",
pages = "87--113",
editor = "{de Souza}, Wanderley",
booktitle = "Structures and organelles in pathogenic protists",

}

RIS

TY - CHAP

T1 - The flagellar pocket of trypanosomatids

T2 - a critical feature for cell morphogenesis and pathogenicity

AU - McKean, Paul

AU - Gull, Keith

PY - 2010

Y1 - 2010

N2 - Trypanosomatids possess a highly ordered array of sub-pellicular microtubules that restrict all vesicular traffic to the flagellar pocket (FP); a small invagination of the plasma membrane located at the base of the flagellum. Although the FP is not an adaptation to parasitism per se, it is without question a key pathogenicity feature that has enabled parasitic trypanosomatid species to exploit a diversity of host environments. In this chapter, we focus on the FP of the African trypanosome Trypanosoma brucei and consider recent advances in our understanding of the physical architecture of the FP and the dynamics of FP operation. We conclude with a brief discussion that the trypanosomatid FP represents an example of “extreme biology”, i.e. a normal but exaggerated example of the cell biology present at the flagellum base in proliferating flagellated eukaryotic cells.

AB - Trypanosomatids possess a highly ordered array of sub-pellicular microtubules that restrict all vesicular traffic to the flagellar pocket (FP); a small invagination of the plasma membrane located at the base of the flagellum. Although the FP is not an adaptation to parasitism per se, it is without question a key pathogenicity feature that has enabled parasitic trypanosomatid species to exploit a diversity of host environments. In this chapter, we focus on the FP of the African trypanosome Trypanosoma brucei and consider recent advances in our understanding of the physical architecture of the FP and the dynamics of FP operation. We conclude with a brief discussion that the trypanosomatid FP represents an example of “extreme biology”, i.e. a normal but exaggerated example of the cell biology present at the flagellum base in proliferating flagellated eukaryotic cells.

KW - Trypanosome

KW - Flagellar Pocket

U2 - 10.1007/978-3-642-12863-9_4

DO - 10.1007/978-3-642-12863-9_4

M3 - Chapter (peer-reviewed)

SN - 9783642128622

T3 - Microbiology Monographs

SP - 87

EP - 113

BT - Structures and organelles in pathogenic protists

A2 - de Souza, Wanderley

PB - Springer Verlag

CY - Berlin

ER -