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The human Achaete-Scute homologue 2 (ASCL2,HASH2) maps to chromosome 11p15.5, close to IGF2 and is expressed in extravillus trophoblasts.

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The human Achaete-Scute homologue 2 (ASCL2,HASH2) maps to chromosome 11p15.5, close to IGF2 and is expressed in extravillus trophoblasts. / Alders, Mariëlle; Hodges, Matt; Hadjantonakis, Anna-Katerina et al.
In: Human Molecular Genetics, Vol. 6, No. 6, 06.1997, p. 859-867.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Alders, M, Hodges, M, Hadjantonakis, A-K, Postmus, J, van Wijk, I, Bliek, J, de Meulemeester, M, Westerveld, A, Guillemot, F, Oudejans, C, Little, P & Mannens, M 1997, 'The human Achaete-Scute homologue 2 (ASCL2,HASH2) maps to chromosome 11p15.5, close to IGF2 and is expressed in extravillus trophoblasts.', Human Molecular Genetics, vol. 6, no. 6, pp. 859-867. https://doi.org/10.1093/hmg/6.6.859

APA

Alders, M., Hodges, M., Hadjantonakis, A-K., Postmus, J., van Wijk, I., Bliek, J., de Meulemeester, M., Westerveld, A., Guillemot, F., Oudejans, C., Little, P., & Mannens, M. (1997). The human Achaete-Scute homologue 2 (ASCL2,HASH2) maps to chromosome 11p15.5, close to IGF2 and is expressed in extravillus trophoblasts. Human Molecular Genetics, 6(6), 859-867. https://doi.org/10.1093/hmg/6.6.859

Vancouver

Alders M, Hodges M, Hadjantonakis A-K, Postmus J, van Wijk I, Bliek J et al. The human Achaete-Scute homologue 2 (ASCL2,HASH2) maps to chromosome 11p15.5, close to IGF2 and is expressed in extravillus trophoblasts. Human Molecular Genetics. 1997 Jun;6(6):859-867. doi: 10.1093/hmg/6.6.859

Author

Alders, Mariëlle ; Hodges, Matt ; Hadjantonakis, Anna-Katerina et al. / The human Achaete-Scute homologue 2 (ASCL2,HASH2) maps to chromosome 11p15.5, close to IGF2 and is expressed in extravillus trophoblasts. In: Human Molecular Genetics. 1997 ; Vol. 6, No. 6. pp. 859-867.

Bibtex

@article{1e13ce7e13a74a21a7aee2bd5fb7b5b7,
title = "The human Achaete-Scute homologue 2 (ASCL2,HASH2) maps to chromosome 11p15.5, close to IGF2 and is expressed in extravillus trophoblasts.",
abstract = "Here we describe the cloning of the human Achaete Scute Homologue 2 (HASH2) gene, officially designated ASCL2 (Achaete Scute complex like 2), a homologue of the DrosophilaAchaete and Scute genes. In mouse, this gene is imprinted and maps to chromosome 7. We mapped the human homologue close to IGF2 and H19 at 11p15.5, the human region syntenic with mouse chromosome 7, indicating that this imprinted region is highly conserved in mouse and man. HASH2 is expressed in the extravillus trophoblasts of the developing placenta only. The lack of HASH2 expression in non-malignant hydatidiform (androgenetic) moles indicates that HASH2 is also imprinted in man.",
keywords = "ASCL2, imprinted",
author = "Mari{\"e}lle Alders and Matt Hodges and Anna-Katerina Hadjantonakis and Jan Postmus and {van Wijk}, Inge and Jet Bliek and {de Meulemeester}, Maurice and Andries Westerveld and Fran{\c c}ois Guillemot and Cees Oudejans and Peter Little and Marcel Mannens",
year = "1997",
month = jun,
doi = "10.1093/hmg/6.6.859",
language = "English",
volume = "6",
pages = "859--867",
journal = "Human Molecular Genetics",
issn = "1460-2083",
publisher = "Oxford University Press",
number = "6",

}

RIS

TY - JOUR

T1 - The human Achaete-Scute homologue 2 (ASCL2,HASH2) maps to chromosome 11p15.5, close to IGF2 and is expressed in extravillus trophoblasts.

AU - Alders, Mariëlle

AU - Hodges, Matt

AU - Hadjantonakis, Anna-Katerina

AU - Postmus, Jan

AU - van Wijk, Inge

AU - Bliek, Jet

AU - de Meulemeester, Maurice

AU - Westerveld, Andries

AU - Guillemot, François

AU - Oudejans, Cees

AU - Little, Peter

AU - Mannens, Marcel

PY - 1997/6

Y1 - 1997/6

N2 - Here we describe the cloning of the human Achaete Scute Homologue 2 (HASH2) gene, officially designated ASCL2 (Achaete Scute complex like 2), a homologue of the DrosophilaAchaete and Scute genes. In mouse, this gene is imprinted and maps to chromosome 7. We mapped the human homologue close to IGF2 and H19 at 11p15.5, the human region syntenic with mouse chromosome 7, indicating that this imprinted region is highly conserved in mouse and man. HASH2 is expressed in the extravillus trophoblasts of the developing placenta only. The lack of HASH2 expression in non-malignant hydatidiform (androgenetic) moles indicates that HASH2 is also imprinted in man.

AB - Here we describe the cloning of the human Achaete Scute Homologue 2 (HASH2) gene, officially designated ASCL2 (Achaete Scute complex like 2), a homologue of the DrosophilaAchaete and Scute genes. In mouse, this gene is imprinted and maps to chromosome 7. We mapped the human homologue close to IGF2 and H19 at 11p15.5, the human region syntenic with mouse chromosome 7, indicating that this imprinted region is highly conserved in mouse and man. HASH2 is expressed in the extravillus trophoblasts of the developing placenta only. The lack of HASH2 expression in non-malignant hydatidiform (androgenetic) moles indicates that HASH2 is also imprinted in man.

KW - ASCL2

KW - imprinted

U2 - 10.1093/hmg/6.6.859

DO - 10.1093/hmg/6.6.859

M3 - Journal article

VL - 6

SP - 859

EP - 867

JO - Human Molecular Genetics

JF - Human Molecular Genetics

SN - 1460-2083

IS - 6

ER -