Home > Research > Publications & Outputs > The impact of different forms of exercise on en...

Links

Text available via DOI:

View graph of relations

The impact of different forms of exercise on endothelial progenitor cells in healthy populations

Research output: Contribution to Journal/MagazineJournal articlepeer-review

Published

Standard

The impact of different forms of exercise on endothelial progenitor cells in healthy populations. / Ferentinos, Panagiotis; Tsakirides, Costas; Swainson, Michelle et al.

In: European Journal of Applied Physiology, Vol. 122, No. 7, 31.07.2022, p. 1589-1625.

Research output: Contribution to Journal/MagazineJournal articlepeer-review

Harvard

Ferentinos, P, Tsakirides, C, Swainson, M, Davison, A, Martyn-St James, M & Ispoglou, T 2022, 'The impact of different forms of exercise on endothelial progenitor cells in healthy populations', European Journal of Applied Physiology, vol. 122, no. 7, pp. 1589-1625. https://doi.org/10.1007/s00421-022-04921-7

APA

Ferentinos, P., Tsakirides, C., Swainson, M., Davison, A., Martyn-St James, M., & Ispoglou, T. (2022). The impact of different forms of exercise on endothelial progenitor cells in healthy populations. European Journal of Applied Physiology, 122(7), 1589-1625. https://doi.org/10.1007/s00421-022-04921-7

Vancouver

Ferentinos P, Tsakirides C, Swainson M, Davison A, Martyn-St James M, Ispoglou T. The impact of different forms of exercise on endothelial progenitor cells in healthy populations. European Journal of Applied Physiology. 2022 Jul 31;122(7):1589-1625. Epub 2022 Mar 19. doi: 10.1007/s00421-022-04921-7

Author

Ferentinos, Panagiotis ; Tsakirides, Costas ; Swainson, Michelle et al. / The impact of different forms of exercise on endothelial progenitor cells in healthy populations. In: European Journal of Applied Physiology. 2022 ; Vol. 122, No. 7. pp. 1589-1625.

Bibtex

@article{dd646391aaac4617921167572c7a3824,
title = "The impact of different forms of exercise on endothelial progenitor cells in healthy populations",
abstract = "Circulating endothelial progenitor cells (EPCs) contribute to vascular healing and neovascularisation, while exercise is an effective means to mobilise EPCs into the circulation. Obhjectives: to systematically examine the acute and chronic effects of different forms of exercise on circulating EPCs in healthy populations. Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines were followed. thirty-one articles met the inclusion criteria including 747 participants aged 19 to 76 years. All included trials used flow cytometry for identification of circulating EPCs. Eight and five different EPC phenotypes were identified in the acute and chronic trials, respectively. In the acute trials, moderate intensity continuous (MICON), maximal, prolonged endurance, resistance and high intensity interval training (HIIT) exercise protocols were utilised. Prolonged endurance and resistance exercise had the most profound effect on circulating EPCs followed by maximal exercise. In the chronic trials, MICON exercise, HIIT, HIIT compared to MICON and MICON compared to exergame (exercise modality based on an interactive video game) were identified. MICON exercise had a positive effect on circulating EPCs in older sedentary individuals which was accompanied by improvements in endothelial function and arterial stiffness. Long-stage HIIT (4 min bouts) appears to be an effective means and superior than MICON exercise in mobilising circulating EPCs. In conclusion, both in acute and chronic trials the degree of exercise-induced EPC mobilisation depends upon the exercise regime applied. In future, more research is warranted to examine the dose-response relationship of different exercise forms on circulating EPCs using standardised methodology and EPC phenotype. ",
keywords = "Cardiometabolic health, EPC mobilisation, Resistance exercise, Endothelial progenitor cells, Aerobic training, Flow cytometry, Exercise, Vascular health, Moderate intensity continuous training, High intensity interval training",
author = "Panagiotis Ferentinos and Costas Tsakirides and Michelle Swainson and Adam Davison and {Martyn-St James}, Marrissa and Theocharis Ispoglou",
year = "2022",
month = jul,
day = "31",
doi = "10.1007/s00421-022-04921-7",
language = "English",
volume = "122",
pages = "1589--1625",
journal = "European Journal of Applied Physiology",
issn = "1439-6319",
publisher = "Springer Verlag",
number = "7",

}

RIS

TY - JOUR

T1 - The impact of different forms of exercise on endothelial progenitor cells in healthy populations

AU - Ferentinos, Panagiotis

AU - Tsakirides, Costas

AU - Swainson, Michelle

AU - Davison, Adam

AU - Martyn-St James, Marrissa

AU - Ispoglou, Theocharis

PY - 2022/7/31

Y1 - 2022/7/31

N2 - Circulating endothelial progenitor cells (EPCs) contribute to vascular healing and neovascularisation, while exercise is an effective means to mobilise EPCs into the circulation. Obhjectives: to systematically examine the acute and chronic effects of different forms of exercise on circulating EPCs in healthy populations. Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines were followed. thirty-one articles met the inclusion criteria including 747 participants aged 19 to 76 years. All included trials used flow cytometry for identification of circulating EPCs. Eight and five different EPC phenotypes were identified in the acute and chronic trials, respectively. In the acute trials, moderate intensity continuous (MICON), maximal, prolonged endurance, resistance and high intensity interval training (HIIT) exercise protocols were utilised. Prolonged endurance and resistance exercise had the most profound effect on circulating EPCs followed by maximal exercise. In the chronic trials, MICON exercise, HIIT, HIIT compared to MICON and MICON compared to exergame (exercise modality based on an interactive video game) were identified. MICON exercise had a positive effect on circulating EPCs in older sedentary individuals which was accompanied by improvements in endothelial function and arterial stiffness. Long-stage HIIT (4 min bouts) appears to be an effective means and superior than MICON exercise in mobilising circulating EPCs. In conclusion, both in acute and chronic trials the degree of exercise-induced EPC mobilisation depends upon the exercise regime applied. In future, more research is warranted to examine the dose-response relationship of different exercise forms on circulating EPCs using standardised methodology and EPC phenotype.

AB - Circulating endothelial progenitor cells (EPCs) contribute to vascular healing and neovascularisation, while exercise is an effective means to mobilise EPCs into the circulation. Obhjectives: to systematically examine the acute and chronic effects of different forms of exercise on circulating EPCs in healthy populations. Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines were followed. thirty-one articles met the inclusion criteria including 747 participants aged 19 to 76 years. All included trials used flow cytometry for identification of circulating EPCs. Eight and five different EPC phenotypes were identified in the acute and chronic trials, respectively. In the acute trials, moderate intensity continuous (MICON), maximal, prolonged endurance, resistance and high intensity interval training (HIIT) exercise protocols were utilised. Prolonged endurance and resistance exercise had the most profound effect on circulating EPCs followed by maximal exercise. In the chronic trials, MICON exercise, HIIT, HIIT compared to MICON and MICON compared to exergame (exercise modality based on an interactive video game) were identified. MICON exercise had a positive effect on circulating EPCs in older sedentary individuals which was accompanied by improvements in endothelial function and arterial stiffness. Long-stage HIIT (4 min bouts) appears to be an effective means and superior than MICON exercise in mobilising circulating EPCs. In conclusion, both in acute and chronic trials the degree of exercise-induced EPC mobilisation depends upon the exercise regime applied. In future, more research is warranted to examine the dose-response relationship of different exercise forms on circulating EPCs using standardised methodology and EPC phenotype.

KW - Cardiometabolic health

KW - EPC mobilisation

KW - Resistance exercise

KW - Endothelial progenitor cells

KW - Aerobic training

KW - Flow cytometry

KW - Exercise

KW - Vascular health

KW - Moderate intensity continuous training

KW - High intensity interval training

UR - http://www.scopus.com/inward/record.url?scp=85126750194&partnerID=8YFLogxK

U2 - 10.1007/s00421-022-04921-7

DO - 10.1007/s00421-022-04921-7

M3 - Journal article

C2 - 35305142

VL - 122

SP - 1589

EP - 1625

JO - European Journal of Applied Physiology

JF - European Journal of Applied Physiology

SN - 1439-6319

IS - 7

ER -