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The nature and dissemination of UHMWPE wear debris retrieved from periprosthetic tissue of THR.

Research output: Contribution to journalJournal articlepeer-review

Published

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The nature and dissemination of UHMWPE wear debris retrieved from periprosthetic tissue of THR. / Elfick, Alistair P. D.; Green, Sarah M.; Krikler, Steve; Unsworth, Anthony.

In: Journal of Biomedical Materials Research Part A, Vol. 65, No. 1, 01.04.2003, p. 95-108.

Research output: Contribution to journalJournal articlepeer-review

Harvard

Elfick, APD, Green, SM, Krikler, S & Unsworth, A 2003, 'The nature and dissemination of UHMWPE wear debris retrieved from periprosthetic tissue of THR.', Journal of Biomedical Materials Research Part A, vol. 65, no. 1, pp. 95-108. https://doi.org/10.1002/jbm.a.10455

APA

Elfick, A. P. D., Green, S. M., Krikler, S., & Unsworth, A. (2003). The nature and dissemination of UHMWPE wear debris retrieved from periprosthetic tissue of THR. Journal of Biomedical Materials Research Part A, 65(1), 95-108. https://doi.org/10.1002/jbm.a.10455

Vancouver

Elfick APD, Green SM, Krikler S, Unsworth A. The nature and dissemination of UHMWPE wear debris retrieved from periprosthetic tissue of THR. Journal of Biomedical Materials Research Part A. 2003 Apr 1;65(1):95-108. https://doi.org/10.1002/jbm.a.10455

Author

Elfick, Alistair P. D. ; Green, Sarah M. ; Krikler, Steve ; Unsworth, Anthony. / The nature and dissemination of UHMWPE wear debris retrieved from periprosthetic tissue of THR. In: Journal of Biomedical Materials Research Part A. 2003 ; Vol. 65, No. 1. pp. 95-108.

Bibtex

@article{b6b5748715064748b242455346573268,
title = "The nature and dissemination of UHMWPE wear debris retrieved from periprosthetic tissue of THR.",
abstract = "The role of wear debris in provoking joint replacement failure through bone resorption is now supported by much research. This study presents the analysis of 104 tissue samples using laser diffraction wear particle analysis in conjunction with standard histologic methods. The number and volume distributions were correlated to a range of joint and patient parameters. The median particle diameter by number was 0.69 μm. No particles smaller than 0.113 μm were resolved. No variation in terms of particle distribution was found among joint types. The ability of particles to migrate away from their point of origin was found to be inversely proportional to their size. The numbers of particles per gram of tissue found in various regions around the prosthesis varied little. Further, the numbers of particles in tissue samples shown to have a chronic foreign-body reaction was > 1 × 109 particles/gram.",
keywords = "THR, prosthetic wear debris , UHMWPE , explanted , dissemination",
author = "Elfick, {Alistair P. D.} and Green, {Sarah M.} and Steve Krikler and Anthony Unsworth",
year = "2003",
month = apr,
day = "1",
doi = "10.1002/jbm.a.10455",
language = "English",
volume = "65",
pages = "95--108",
journal = "Journal of Biomedical Materials Research Part A",
issn = "1549-3296",
publisher = "John Wiley and Sons Inc.",
number = "1",

}

RIS

TY - JOUR

T1 - The nature and dissemination of UHMWPE wear debris retrieved from periprosthetic tissue of THR.

AU - Elfick, Alistair P. D.

AU - Green, Sarah M.

AU - Krikler, Steve

AU - Unsworth, Anthony

PY - 2003/4/1

Y1 - 2003/4/1

N2 - The role of wear debris in provoking joint replacement failure through bone resorption is now supported by much research. This study presents the analysis of 104 tissue samples using laser diffraction wear particle analysis in conjunction with standard histologic methods. The number and volume distributions were correlated to a range of joint and patient parameters. The median particle diameter by number was 0.69 μm. No particles smaller than 0.113 μm were resolved. No variation in terms of particle distribution was found among joint types. The ability of particles to migrate away from their point of origin was found to be inversely proportional to their size. The numbers of particles per gram of tissue found in various regions around the prosthesis varied little. Further, the numbers of particles in tissue samples shown to have a chronic foreign-body reaction was > 1 × 109 particles/gram.

AB - The role of wear debris in provoking joint replacement failure through bone resorption is now supported by much research. This study presents the analysis of 104 tissue samples using laser diffraction wear particle analysis in conjunction with standard histologic methods. The number and volume distributions were correlated to a range of joint and patient parameters. The median particle diameter by number was 0.69 μm. No particles smaller than 0.113 μm were resolved. No variation in terms of particle distribution was found among joint types. The ability of particles to migrate away from their point of origin was found to be inversely proportional to their size. The numbers of particles per gram of tissue found in various regions around the prosthesis varied little. Further, the numbers of particles in tissue samples shown to have a chronic foreign-body reaction was > 1 × 109 particles/gram.

KW - THR

KW - prosthetic wear debris

KW - UHMWPE

KW - explanted

KW - dissemination

U2 - 10.1002/jbm.a.10455

DO - 10.1002/jbm.a.10455

M3 - Journal article

VL - 65

SP - 95

EP - 108

JO - Journal of Biomedical Materials Research Part A

JF - Journal of Biomedical Materials Research Part A

SN - 1549-3296

IS - 1

ER -