The Oxfordshire Community Stroke Project classification in the early hours of ischemic stroke and relation to infarct site and size on cranial computed tomography

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The Oxfordshire Community Stroke Project classification in the early hours of ischemic stroke and relation to infarct site and size on cranial computed tomography. / Smith, Craig J.; Emsley, Hedley C. A.; Libetta, Carole M. et al.
In: Journal of Stroke and Cerebrovascular Diseases, Vol. 10, No. 5, 09.2001, p. 205-209.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Smith, CJ, Emsley, HCA, Libetta, CM, Hughes, DG, Drennan, RF, Vail, A & Tyrrell, PJ 2001, 'The Oxfordshire Community Stroke Project classification in the early hours of ischemic stroke and relation to infarct site and size on cranial computed tomography', Journal of Stroke and Cerebrovascular Diseases, vol. 10, no. 5, pp. 205-209. https://doi.org/10.1053/jscd.2001.29825

APA

Smith, C. J., Emsley, H. C. A., Libetta, C. M., Hughes, D. G., Drennan, R. F., Vail, A., & Tyrrell, P. J. (2001). The Oxfordshire Community Stroke Project classification in the early hours of ischemic stroke and relation to infarct site and size on cranial computed tomography. Journal of Stroke and Cerebrovascular Diseases, 10(5), 205-209. https://doi.org/10.1053/jscd.2001.29825

Vancouver

Smith CJ, Emsley HCA, Libetta CM, Hughes DG, Drennan RF, Vail A et al. The Oxfordshire Community Stroke Project classification in the early hours of ischemic stroke and relation to infarct site and size on cranial computed tomography. Journal of Stroke and Cerebrovascular Diseases. 2001 Sept;10(5):205-209. doi: 10.1053/jscd.2001.29825

Author

Smith, Craig J. ; Emsley, Hedley C. A. ; Libetta, Carole M. et al. / The Oxfordshire Community Stroke Project classification in the early hours of ischemic stroke and relation to infarct site and size on cranial computed tomography. In: Journal of Stroke and Cerebrovascular Diseases. 2001 ; Vol. 10, No. 5. pp. 205-209.

Bibtex

@article{09a8449043b642429abcaa2413ad5d18,

title = "The Oxfordshire Community Stroke Project classification in the early hours of ischemic stroke and relation to infarct site and size on cranial computed tomography",

abstract = "Background and Purpose: The Oxfordshire Community Stroke Project (OCSP) classification clinically subdivides cerebral infarction into total anterior circulation (TACS), partial anterior circulation (PACS), posterior circulation (POCS) and lacunar (LACS) syndromes. We compared the OCSP classification in patients presenting within 12 hours of onset of stroke with infarct site and size on computed tomography (CT) brain scan at 5 to 7 days. Methods: OCSP classification was prospectively assigned by 1 of 3 observers in 43 patients presenting within 12 hours of stroke. CT brain scan was performed on admission to exclude primary intracerebral hemorrhage. Repeat CT brain scan at 5 to 7 days was used to classify recent visible infarction as total anterior circulation infarction (TACI), partial anterior circulation infarction (PACI), lacunar circulation infarction (LACI), or posterior circulation infarction (POCI). For each OCSP subtype, sensitivity and specificity were calculated by using CT classification as a standard. Results: Median (range) interval from onset of stroke symptoms to OCSP classification was 5.0 (1.5, 11.75) hours. Thirty-seven patients had ischemic stroke, with recent visible infarction in 34 (92%). Sensitivity and specificity of each OCSP subtype was TACS (0.80, 0.82), PACS (0.56, 0.79), LACS (0.33, 0.88), and POCS (1.00, 0.97). Overall, 65% of OCSP subtypes assigned were correct when compared to CT classification. Conclusions: In this small study, we have shown that the OCSP classification within 12 hours of ischemic stroke onset compares with CT classification at 5 to 7 days. Larger studies are required to evaluate the validity of the OCSP classification in the early hours of ischemic stroke in guiding appropriate patient selection for acute stroke therapy and interventions.",

keywords = "Acute stroke, Cerebral infarction, Computed tomography, Stroke classification",

author = "Smith, {Craig J.} and Emsley, {Hedley C. A.} and Libetta, {Carole M.} and Hughes, {David G.} and Drennan, {Rachel F.} and Andy Vail and Tyrrell, {Pippa J.}",

year = "2001",

month = sep,

doi = "10.1053/jscd.2001.29825",

language = "English",

volume = "10",

pages = "205--209",

journal = "Journal of Stroke and Cerebrovascular Diseases",

issn = "1052-3057",

publisher = "W.B. Saunders Ltd",

number = "5",

}

RIS

TY - JOUR

T1 - The Oxfordshire Community Stroke Project classification in the early hours of ischemic stroke and relation to infarct site and size on cranial computed tomography

AU - Smith, Craig J.

AU - Emsley, Hedley C. A.

AU - Libetta, Carole M.

AU - Hughes, David G.

AU - Drennan, Rachel F.

AU - Vail, Andy

AU - Tyrrell, Pippa J.

PY - 2001/9

Y1 - 2001/9

N2 - Background and Purpose: The Oxfordshire Community Stroke Project (OCSP) classification clinically subdivides cerebral infarction into total anterior circulation (TACS), partial anterior circulation (PACS), posterior circulation (POCS) and lacunar (LACS) syndromes. We compared the OCSP classification in patients presenting within 12 hours of onset of stroke with infarct site and size on computed tomography (CT) brain scan at 5 to 7 days. Methods: OCSP classification was prospectively assigned by 1 of 3 observers in 43 patients presenting within 12 hours of stroke. CT brain scan was performed on admission to exclude primary intracerebral hemorrhage. Repeat CT brain scan at 5 to 7 days was used to classify recent visible infarction as total anterior circulation infarction (TACI), partial anterior circulation infarction (PACI), lacunar circulation infarction (LACI), or posterior circulation infarction (POCI). For each OCSP subtype, sensitivity and specificity were calculated by using CT classification as a standard. Results: Median (range) interval from onset of stroke symptoms to OCSP classification was 5.0 (1.5, 11.75) hours. Thirty-seven patients had ischemic stroke, with recent visible infarction in 34 (92%). Sensitivity and specificity of each OCSP subtype was TACS (0.80, 0.82), PACS (0.56, 0.79), LACS (0.33, 0.88), and POCS (1.00, 0.97). Overall, 65% of OCSP subtypes assigned were correct when compared to CT classification. Conclusions: In this small study, we have shown that the OCSP classification within 12 hours of ischemic stroke onset compares with CT classification at 5 to 7 days. Larger studies are required to evaluate the validity of the OCSP classification in the early hours of ischemic stroke in guiding appropriate patient selection for acute stroke therapy and interventions.

AB - Background and Purpose: The Oxfordshire Community Stroke Project (OCSP) classification clinically subdivides cerebral infarction into total anterior circulation (TACS), partial anterior circulation (PACS), posterior circulation (POCS) and lacunar (LACS) syndromes. We compared the OCSP classification in patients presenting within 12 hours of onset of stroke with infarct site and size on computed tomography (CT) brain scan at 5 to 7 days. Methods: OCSP classification was prospectively assigned by 1 of 3 observers in 43 patients presenting within 12 hours of stroke. CT brain scan was performed on admission to exclude primary intracerebral hemorrhage. Repeat CT brain scan at 5 to 7 days was used to classify recent visible infarction as total anterior circulation infarction (TACI), partial anterior circulation infarction (PACI), lacunar circulation infarction (LACI), or posterior circulation infarction (POCI). For each OCSP subtype, sensitivity and specificity were calculated by using CT classification as a standard. Results: Median (range) interval from onset of stroke symptoms to OCSP classification was 5.0 (1.5, 11.75) hours. Thirty-seven patients had ischemic stroke, with recent visible infarction in 34 (92%). Sensitivity and specificity of each OCSP subtype was TACS (0.80, 0.82), PACS (0.56, 0.79), LACS (0.33, 0.88), and POCS (1.00, 0.97). Overall, 65% of OCSP subtypes assigned were correct when compared to CT classification. Conclusions: In this small study, we have shown that the OCSP classification within 12 hours of ischemic stroke onset compares with CT classification at 5 to 7 days. Larger studies are required to evaluate the validity of the OCSP classification in the early hours of ischemic stroke in guiding appropriate patient selection for acute stroke therapy and interventions.

KW - Acute stroke

KW - Cerebral infarction

KW - Computed tomography

KW - Stroke classification

U2 - 10.1053/jscd.2001.29825

DO - 10.1053/jscd.2001.29825

M3 - Journal article

AN - SCOPUS:0035672059

VL - 10

SP - 205

EP - 209

JO - Journal of Stroke and Cerebrovascular Diseases

JF - Journal of Stroke and Cerebrovascular Diseases

SN - 1052-3057

IS - 5

ER -

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