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The rise in computational systems biology approaches for understanding NF-κB signaling dynamics

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Article numberfs13
<mark>Journal publication date</mark>14/07/2015
<mark>Journal</mark>Science Signaling
Issue number385
Volume8
Number of pages2
Publication StatusPublished
<mark>Original language</mark>English

Abstract

A study by Cheng et al. in this issue of Science Signaling highlights the distinct
single-cell signaling characteristics conferred by pathways mediated by the adaptor proteins MyD88 and TRIF in the TLR4-dependent activation of the transcription factor nuclear factor κB (NF-κB).