Final published version
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
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TY - JOUR
T1 - The use of vibrational spectroscopy to study the pathogenesis multiple sclerosis and other neurological conditions
AU - Ramos, I.R.
AU - Lyng, F.M.
AU - Rehman, I.U.
AU - Sharrack, B.
AU - Woodroofe, M.N.
PY - 2017/10/1
Y1 - 2017/10/1
N2 - Spectroscopy techniques are valuable tools in biomedical research and have been used extensively in the study of disease. However, neurological conditions such as multiple sclerosis (MS) have received little attention and the available spectroscopy studies are limited, both in overall numbers of patients studied and the disease samples considered. MS is a complex immune-mediated disease, with variable clinical courses and limited therapeutic options. This review aims to summarize current literature in the area, demonstrating how spectroscopy techniques can provide valuable information to inform and advance research into the most common neurological condition affecting young adults.
AB - Spectroscopy techniques are valuable tools in biomedical research and have been used extensively in the study of disease. However, neurological conditions such as multiple sclerosis (MS) have received little attention and the available spectroscopy studies are limited, both in overall numbers of patients studied and the disease samples considered. MS is a complex immune-mediated disease, with variable clinical courses and limited therapeutic options. This review aims to summarize current literature in the area, demonstrating how spectroscopy techniques can provide valuable information to inform and advance research into the most common neurological condition affecting young adults.
KW - Multiple sclerosis
KW - normal-appearing white matter
KW - pathology
KW - spectroscopy
KW - Neurology
KW - Pathology
KW - Biomedical research
KW - Clinical course
KW - White matter
KW - Young adults
KW - Spectroscopy
U2 - 10.1080/05704928.2017.1336450
DO - 10.1080/05704928.2017.1336450
M3 - Journal article
VL - 52
SP - 868
EP - 882
JO - APPLIED SPECTROSCOPY REVIEWS
JF - APPLIED SPECTROSCOPY REVIEWS
SN - 0570-4928
IS - 10
ER -