Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
}
TY - JOUR
T1 - Therapeutic cloning: The ethical limits.
AU - Whittaker, Peter
PY - 2005/9
Y1 - 2005/9
N2 - A brief outline of stem cells, stem cell therapy and therapeutic cloning is given. The position of therapeutic cloning with regard to other embryonic manipulations – IVF-based reproduction, embryonic stem formation from IVF embryos and reproductive cloning – is indicated. The main ethically challenging stages in therapeutic cloning are considered to be the nuclear transfer process including the source of eggs for this and the destruction of an embryo to provide stem cells for therapeutic use. The extremely polarised nature of the debate regarding the status of an early human embryo is noted, and some potential alternative strategies for preparing immunocompatible pluripotent stem cells are indicated.
AB - A brief outline of stem cells, stem cell therapy and therapeutic cloning is given. The position of therapeutic cloning with regard to other embryonic manipulations – IVF-based reproduction, embryonic stem formation from IVF embryos and reproductive cloning – is indicated. The main ethically challenging stages in therapeutic cloning are considered to be the nuclear transfer process including the source of eggs for this and the destruction of an embryo to provide stem cells for therapeutic use. The extremely polarised nature of the debate regarding the status of an early human embryo is noted, and some potential alternative strategies for preparing immunocompatible pluripotent stem cells are indicated.
KW - Therapeutic cloning
KW - Stem cells
KW - Ethics
U2 - 10.1016/j.taap.2004.11.034
DO - 10.1016/j.taap.2004.11.034
M3 - Journal article
VL - 207
SP - 689
EP - 691
JO - Toxicology and Applied Pharmacology
JF - Toxicology and Applied Pharmacology
SN - 1096-0333
IS - 2
ER -