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Thermal depletion of calcium pools in the smooth muscle of the flounder gut.

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Thermal depletion of calcium pools in the smooth muscle of the flounder gut. / Lennard, R.; Huddart, H.
In: Comparative Biochemistry and Physiology Part C: Comparative Pharmacology, Vol. 101, No. 2, 02.1992, p. 311-316.

Research output: Contribution to Journal/Magazine › Journal article

Harvard

Lennard, R & Huddart, H 1992, 'Thermal depletion of calcium pools in the smooth muscle of the flounder gut.', Comparative Biochemistry and Physiology Part C: Comparative Pharmacology, vol. 101, no. 2, pp. 311-316. https://doi.org/10.1016/0742-8413(92)90279-G

APA

Lennard, R., & Huddart, H. (1992). Thermal depletion of calcium pools in the smooth muscle of the flounder gut. Comparative Biochemistry and Physiology Part C: Comparative Pharmacology, 101(2), 311-316. https://doi.org/10.1016/0742-8413(92)90279-G

Vancouver

Lennard R, Huddart H. Thermal depletion of calcium pools in the smooth muscle of the flounder gut. Comparative Biochemistry and Physiology Part C: Comparative Pharmacology. 1992 Feb;101(2):311-316. doi: 10.1016/0742-8413(92)90279-G

Author

Lennard, R. ; Huddart, H. / Thermal depletion of calcium pools in the smooth muscle of the flounder gut. In: Comparative Biochemistry and Physiology Part C: Comparative Pharmacology. 1992 ; Vol. 101, No. 2. pp. 311-316.

Bibtex

@article{4b4fe49b1cf9476cbf84f2422a38e12e,
title = "Thermal depletion of calcium pools in the smooth muscle of the flounder gut.",
abstract = "1. Efflux of radiocalcium from both microsomal and mitochondrial fractions of flounder ileum was potentiated in the presence of caffeine. In the presence of ACh an increase in radiocaleium efflux was only observed in microsomal fractions. 2. Sections of spontaneously active flounder ileum maintained at 10°C became quiescent when placed in calcium-free media. The tissue then exhibited several single contractions in response to small doses of either caffeine or acetylcholine (ACh). 3. After several additions of either caffeine or ACh tissues failed to respond. 4. The number of doses of ACh or caffeine required before tissues failed to contract was strongly temperature dependent. 5. In the presence of ACh ileal cells were seen to depolarize whereas the presence of caffeine lead to hyperpolarization. 6. It is concluded that caffeine and ACh access different elements of smooth muscle cellular calcium pools and the ability to access these pools is temperature dependent.",
author = "R. Lennard and H. Huddart",
year = "1992",
month = feb,
doi = "10.1016/0742-8413(92)90279-G",
language = "English",
volume = "101",
pages = "311--316",
journal = "Comparative Biochemistry and Physiology Part C: Comparative Pharmacology",
publisher = "Elsevier BV",
number = "2",

}

RIS

TY - JOUR

T1 - Thermal depletion of calcium pools in the smooth muscle of the flounder gut.

AU - Lennard, R.

AU - Huddart, H.

PY - 1992/2

Y1 - 1992/2

N2 - 1. Efflux of radiocalcium from both microsomal and mitochondrial fractions of flounder ileum was potentiated in the presence of caffeine. In the presence of ACh an increase in radiocaleium efflux was only observed in microsomal fractions. 2. Sections of spontaneously active flounder ileum maintained at 10°C became quiescent when placed in calcium-free media. The tissue then exhibited several single contractions in response to small doses of either caffeine or acetylcholine (ACh). 3. After several additions of either caffeine or ACh tissues failed to respond. 4. The number of doses of ACh or caffeine required before tissues failed to contract was strongly temperature dependent. 5. In the presence of ACh ileal cells were seen to depolarize whereas the presence of caffeine lead to hyperpolarization. 6. It is concluded that caffeine and ACh access different elements of smooth muscle cellular calcium pools and the ability to access these pools is temperature dependent.

AB - 1. Efflux of radiocalcium from both microsomal and mitochondrial fractions of flounder ileum was potentiated in the presence of caffeine. In the presence of ACh an increase in radiocaleium efflux was only observed in microsomal fractions. 2. Sections of spontaneously active flounder ileum maintained at 10°C became quiescent when placed in calcium-free media. The tissue then exhibited several single contractions in response to small doses of either caffeine or acetylcholine (ACh). 3. After several additions of either caffeine or ACh tissues failed to respond. 4. The number of doses of ACh or caffeine required before tissues failed to contract was strongly temperature dependent. 5. In the presence of ACh ileal cells were seen to depolarize whereas the presence of caffeine lead to hyperpolarization. 6. It is concluded that caffeine and ACh access different elements of smooth muscle cellular calcium pools and the ability to access these pools is temperature dependent.

U2 - 10.1016/0742-8413(92)90279-G

DO - 10.1016/0742-8413(92)90279-G

M3 - Journal article

VL - 101

SP - 311

EP - 316

JO - Comparative Biochemistry and Physiology Part C: Comparative Pharmacology

JF - Comparative Biochemistry and Physiology Part C: Comparative Pharmacology

IS - 2

ER -