Research output: Contribution to Journal/Magazine › Literature review › peer-review
Thermotropic liquid crystalline glycolipids. / Goodby, J. W.; Goertz, V.; Cowling, S. J. et al.
In: Chemical Society Reviews, Vol. 36, No. 12, 2007, p. 1971-2032.Research output: Contribution to Journal/Magazine › Literature review › peer-review
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TY - JOUR
T1 - Thermotropic liquid crystalline glycolipids
AU - Goodby, J. W.
AU - Goertz, V.
AU - Cowling, S. J.
AU - Mackenzie, G.
AU - Martin, P.
AU - Plusquellec, D.
AU - Benvegnu, T.
AU - Boullanger, P.
AU - Lafont, D.
AU - Queneau, Y.
AU - Chambert, S.
AU - Fitremann, J.
PY - 2007
Y1 - 2007
N2 - Are the liquid crystalline properties of the materials of living systems important in biological structures, functions, diseases and treatments? There is a growing consciousness that the observed lyotropic, and often thermotropic liquid crystallinity, of many biological materials that possess key biological functionality might be more than curious coincidence. Rather, as the survival of living systems depends on the flexibility and reformability of structures, it seems more likely that it is the combination of softness and structure of the liquid- crystalline state that determines the functionality of biological materials. The richest sources of liquid crystals derived from living systems are found in cell membranes, of these glycolipids are a particularly important class of components. In this critical review, we will examine the relationship between chemical structure and the self- assembling and self- organising properties of glycolipids that ultimately lead to mesophase formation.
AB - Are the liquid crystalline properties of the materials of living systems important in biological structures, functions, diseases and treatments? There is a growing consciousness that the observed lyotropic, and often thermotropic liquid crystallinity, of many biological materials that possess key biological functionality might be more than curious coincidence. Rather, as the survival of living systems depends on the flexibility and reformability of structures, it seems more likely that it is the combination of softness and structure of the liquid- crystalline state that determines the functionality of biological materials. The richest sources of liquid crystals derived from living systems are found in cell membranes, of these glycolipids are a particularly important class of components. In this critical review, we will examine the relationship between chemical structure and the self- assembling and self- organising properties of glycolipids that ultimately lead to mesophase formation.
KW - OLEFIN CROSS-METATHESIS
KW - D-ERYTHRO-SPHINGOSINE
KW - CATALYZED REGIOSELECTIVE ESTERIFICATION
KW - DIFFERENTIAL SCANNING CALORIMETRY
KW - ARCHAEBACTERIAL MEMBRANE-LIPIDS
KW - SUCROSE HYDROXYALKYL ETHERS
KW - CARBOHYDRATE-BASED MESOGENS
KW - SELF-ORGANIZING PROPERTIES
KW - PHASE-TRANSFER CATALYSIS
KW - METHANOSPIRILLUM-HUNGATEI
U2 - 10.1039/b708458g
DO - 10.1039/b708458g
M3 - Literature review
VL - 36
SP - 1971
EP - 2032
JO - Chemical Society Reviews
JF - Chemical Society Reviews
SN - 0306-0012
IS - 12
ER -