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Titanium-containing bioactive phosphate glasses

Research output: Contribution to journalJournal articlepeer-review

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  • Azadeh Kiani
  • Nilay J. Lakhkar
  • Vehid Salih
  • Mark E. Smith
  • John V. Hanna
  • Robert J. Newport
  • David M. Pickup
  • Jonathan C. Knowles
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<mark>Journal publication date</mark>20/02/2012
<mark>Journal</mark>Philosophical Transactions of the Royal Society A: Mathematical, Physical & Engineering Sciences
Issue number1963
Volume370
Number of pages24
Pages (from-to)1352-1375
Publication StatusPublished
<mark>Original language</mark>English

Abstract

The use of biomaterials has revolutionized the biomedical field and has received substantial attention in the last two decades. Among the various types of biomaterials, phosphate glasses have generated great interest on account of their remarkable bioactivity and favourable physical properties for various biomedical applications relating to both hard and soft tissue regeneration. This review paper focuses mainly on the development of titanium-containing phosphate-based glasses and presents an overview of the structural and physical properties. The effect of titanium incorporation on the glassy network is to introduce favourable properties. The biocompatibility of these glasses is described along with recent developments in processing methodologies, and the potential of Ti-containing phosphate-based glasses as a bone substitute material is explored.