Home > Research > Publications & Outputs > Towards a standard battery of microsatellite ma...

Research

Links

Text available via DOI:

View graph of relations

Towards a standard battery of microsatellite markers for the analysis of the Leishmania donovani complex

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Published

Standard

Towards a standard battery of microsatellite markers for the analysis of the Leishmania donovani complex. / Jamjoom, M B; Ashford, R W; Bates, P A et al.
In: Annals of Tropical Medicine and Parasitology, Vol. 96, No. 3, 04.2002, p. 265-270.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Jamjoom, MB, Ashford, RW, Bates, PA, Kemp, SJ & Noyes, HA 2002, 'Towards a standard battery of microsatellite markers for the analysis of the Leishmania donovani complex', Annals of Tropical Medicine and Parasitology, vol. 96, no. 3, pp. 265-270. https://doi.org/10.1179/000349802125000790

APA

Jamjoom, M. B., Ashford, R. W., Bates, P. A., Kemp, S. J., & Noyes, H. A. (2002). Towards a standard battery of microsatellite markers for the analysis of the Leishmania donovani complex. Annals of Tropical Medicine and Parasitology, 96(3), 265-270. https://doi.org/10.1179/000349802125000790

Vancouver

Jamjoom MB, Ashford RW, Bates PA, Kemp SJ, Noyes HA. Towards a standard battery of microsatellite markers for the analysis of the Leishmania donovani complex. Annals of Tropical Medicine and Parasitology. 2002 Apr;96(3):265-270. doi: 10.1179/000349802125000790

Author

Jamjoom, M B ; Ashford, R W ; Bates, P A et al. / Towards a standard battery of microsatellite markers for the analysis of the Leishmania donovani complex. In: Annals of Tropical Medicine and Parasitology. 2002 ; Vol. 96, No. 3. pp. 265-270.

Bibtex

@article{41a411a4611e4647ae4bec96c177022b,
title = "Towards a standard battery of microsatellite markers for the analysis of the Leishmania donovani complex",
abstract = "The investigation of microsatellite markers has recently superseded that of isoenzymes for many population-biology applications. Microsatellites have the advantages of being dominant, neutral, highly polymorphic and easily scored by high-throughput methods. However, it is necessary to develop a new panel of markers for each group of organisms of interest. Previously, only about 5% of the markers that amplify Leishmania major microsatellite loci were also found to amplify L. donovani loci. A panel of 20 microsatellite markers that are polymorphic in L. donovani and L. infantum has now been developed, using a rapid-enrichment method that will be suitable for developing libraries of markers for other trypanosomatid species. This is the first panel of polymorphic microsatellite markers, to be isolated de novo from any species of Leishmania, that is large enough for population-biology applications.",
author = "Jamjoom, {M B} and Ashford, {R W} and Bates, {P A} and Kemp, {S J} and Noyes, {H A}",
year = "2002",
month = apr,
doi = "10.1179/000349802125000790",
language = "English",
volume = "96",
pages = "265--270",
journal = "Annals of Tropical Medicine and Parasitology",
issn = "0003-4983",
publisher = "Maney Publishing",
number = "3",

}

RIS

TY - JOUR

T1 - Towards a standard battery of microsatellite markers for the analysis of the Leishmania donovani complex

AU - Jamjoom, M B

AU - Ashford, R W

AU - Bates, P A

AU - Kemp, S J

AU - Noyes, H A

PY - 2002/4

Y1 - 2002/4

N2 - The investigation of microsatellite markers has recently superseded that of isoenzymes for many population-biology applications. Microsatellites have the advantages of being dominant, neutral, highly polymorphic and easily scored by high-throughput methods. However, it is necessary to develop a new panel of markers for each group of organisms of interest. Previously, only about 5% of the markers that amplify Leishmania major microsatellite loci were also found to amplify L. donovani loci. A panel of 20 microsatellite markers that are polymorphic in L. donovani and L. infantum has now been developed, using a rapid-enrichment method that will be suitable for developing libraries of markers for other trypanosomatid species. This is the first panel of polymorphic microsatellite markers, to be isolated de novo from any species of Leishmania, that is large enough for population-biology applications.

AB - The investigation of microsatellite markers has recently superseded that of isoenzymes for many population-biology applications. Microsatellites have the advantages of being dominant, neutral, highly polymorphic and easily scored by high-throughput methods. However, it is necessary to develop a new panel of markers for each group of organisms of interest. Previously, only about 5% of the markers that amplify Leishmania major microsatellite loci were also found to amplify L. donovani loci. A panel of 20 microsatellite markers that are polymorphic in L. donovani and L. infantum has now been developed, using a rapid-enrichment method that will be suitable for developing libraries of markers for other trypanosomatid species. This is the first panel of polymorphic microsatellite markers, to be isolated de novo from any species of Leishmania, that is large enough for population-biology applications.

U2 - 10.1179/000349802125000790

DO - 10.1179/000349802125000790

M3 - Journal article

C2 - 12061973

VL - 96

SP - 265

EP - 270

JO - Annals of Tropical Medicine and Parasitology

JF - Annals of Tropical Medicine and Parasitology

SN - 0003-4983

IS - 3

ER -