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Tracking the introduction and spread of SARS-CoV-2 in coastal Kenya

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Tracking the introduction and spread of SARS-CoV-2 in coastal Kenya. / Githinji, George; Laurent, Zaydah R. de; Mohammed, Khadija Said et al.
In: Nature Communications, Vol. 12, No. 1, 4809, 10.08.2021.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Githinji, G, Laurent, ZRD, Mohammed, KS, Omuoyo, DO, Macharia, PM, Morobe, JM, Otieno, E, Kinyanjui, SM, Agweyu, A, Maitha, E, Kitole, B, Suleiman, T, Mwakinangu, M, Nyambu, J, Otieno, J, Salim, B, Kasera, K, Kiiru, J, Aman, R, Barasa, E, Warimwe, G, Bejon, P, Tsofa, B, Ochola-Oyier, LI, Nokes, DJ & Agoti, CN 2021, 'Tracking the introduction and spread of SARS-CoV-2 in coastal Kenya', Nature Communications, vol. 12, no. 1, 4809. https://doi.org/10.1038/s41467-021-25137-x

APA

Githinji, G., Laurent, Z. R. D., Mohammed, K. S., Omuoyo, D. O., Macharia, P. M., Morobe, J. M., Otieno, E., Kinyanjui, S. M., Agweyu, A., Maitha, E., Kitole, B., Suleiman, T., Mwakinangu, M., Nyambu, J., Otieno, J., Salim, B., Kasera, K., Kiiru, J., Aman, R., ... Agoti, C. N. (2021). Tracking the introduction and spread of SARS-CoV-2 in coastal Kenya. Nature Communications, 12(1), Article 4809. https://doi.org/10.1038/s41467-021-25137-x

Vancouver

Githinji G, Laurent ZRD, Mohammed KS, Omuoyo DO, Macharia PM, Morobe JM et al. Tracking the introduction and spread of SARS-CoV-2 in coastal Kenya. Nature Communications. 2021 Aug 10;12(1):4809. doi: 10.1038/s41467-021-25137-x

Author

Githinji, George ; Laurent, Zaydah R. de ; Mohammed, Khadija Said et al. / Tracking the introduction and spread of SARS-CoV-2 in coastal Kenya. In: Nature Communications. 2021 ; Vol. 12, No. 1.

Bibtex

@article{ad8b2a371130417d97f53b4fc18903ce,
title = "Tracking the introduction and spread of SARS-CoV-2 in coastal Kenya",
abstract = "Genomic surveillance of SARS-CoV-2 is important for understanding both the evolution and the patterns of local and global transmission. Here, we generated 311 SARS-CoV-2 genomes from samples collected in coastal Kenya between 17 th March and 31 st July 2020. We estimated multiple independent SARS-CoV-2 introductions into the region were primarily of European origin, although introductions could have come through neighbouring countries. Lineage B.1 accounted for 74% of sequenced cases. Lineages A, B and B.4 were detected in screened individuals at the Kenya-Tanzania border or returning travellers. Though multiple lineages were introduced into coastal Kenya following the initial confirmed case, none showed extensive local expansion other than lineage B.1. International points of entry were important conduits of SARS-CoV-2 importations into coastal Kenya and early public health responses prevented established transmission of some lineages. Undetected introductions through points of entry including imports from elsewhere in the country gave rise to the local epidemic at the Kenyan coast. ",
author = "George Githinji and Laurent, {Zaydah R. de} and Mohammed, {Khadija Said} and Omuoyo, {Donwilliams O.} and Macharia, {Peter M.} and Morobe, {John M.} and Edward Otieno and Kinyanjui, {Samson M.} and Ambrose Agweyu and Eric Maitha and Ben Kitole and Thani Suleiman and Mohamed Mwakinangu and John Nyambu and John Otieno and Barke Salim and Kadondi Kasera and John Kiiru and Rashid Aman and Edwine Barasa and George Warimwe and Philip Bejon and Benjamin Tsofa and Ochola-Oyier, {Lynette Isabella} and Nokes, {D. James} and Agoti, {Charles N.}",
year = "2021",
month = aug,
day = "10",
doi = "10.1038/s41467-021-25137-x",
language = "English",
volume = "12",
journal = "Nature Communications",
issn = "2041-1723",
publisher = "Nature Publishing Group",
number = "1",

}

RIS

TY - JOUR

T1 - Tracking the introduction and spread of SARS-CoV-2 in coastal Kenya

AU - Githinji, George

AU - Laurent, Zaydah R. de

AU - Mohammed, Khadija Said

AU - Omuoyo, Donwilliams O.

AU - Macharia, Peter M.

AU - Morobe, John M.

AU - Otieno, Edward

AU - Kinyanjui, Samson M.

AU - Agweyu, Ambrose

AU - Maitha, Eric

AU - Kitole, Ben

AU - Suleiman, Thani

AU - Mwakinangu, Mohamed

AU - Nyambu, John

AU - Otieno, John

AU - Salim, Barke

AU - Kasera, Kadondi

AU - Kiiru, John

AU - Aman, Rashid

AU - Barasa, Edwine

AU - Warimwe, George

AU - Bejon, Philip

AU - Tsofa, Benjamin

AU - Ochola-Oyier, Lynette Isabella

AU - Nokes, D. James

AU - Agoti, Charles N.

PY - 2021/8/10

Y1 - 2021/8/10

N2 - Genomic surveillance of SARS-CoV-2 is important for understanding both the evolution and the patterns of local and global transmission. Here, we generated 311 SARS-CoV-2 genomes from samples collected in coastal Kenya between 17 th March and 31 st July 2020. We estimated multiple independent SARS-CoV-2 introductions into the region were primarily of European origin, although introductions could have come through neighbouring countries. Lineage B.1 accounted for 74% of sequenced cases. Lineages A, B and B.4 were detected in screened individuals at the Kenya-Tanzania border or returning travellers. Though multiple lineages were introduced into coastal Kenya following the initial confirmed case, none showed extensive local expansion other than lineage B.1. International points of entry were important conduits of SARS-CoV-2 importations into coastal Kenya and early public health responses prevented established transmission of some lineages. Undetected introductions through points of entry including imports from elsewhere in the country gave rise to the local epidemic at the Kenyan coast.

AB - Genomic surveillance of SARS-CoV-2 is important for understanding both the evolution and the patterns of local and global transmission. Here, we generated 311 SARS-CoV-2 genomes from samples collected in coastal Kenya between 17 th March and 31 st July 2020. We estimated multiple independent SARS-CoV-2 introductions into the region were primarily of European origin, although introductions could have come through neighbouring countries. Lineage B.1 accounted for 74% of sequenced cases. Lineages A, B and B.4 were detected in screened individuals at the Kenya-Tanzania border or returning travellers. Though multiple lineages were introduced into coastal Kenya following the initial confirmed case, none showed extensive local expansion other than lineage B.1. International points of entry were important conduits of SARS-CoV-2 importations into coastal Kenya and early public health responses prevented established transmission of some lineages. Undetected introductions through points of entry including imports from elsewhere in the country gave rise to the local epidemic at the Kenyan coast.

U2 - 10.1038/s41467-021-25137-x

DO - 10.1038/s41467-021-25137-x

M3 - Journal article

C2 - 34376689

VL - 12

JO - Nature Communications

JF - Nature Communications

SN - 2041-1723

IS - 1

M1 - 4809

ER -