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Transforming growth factor betas in mammalian embryogenesis

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Transforming growth factor betas in mammalian embryogenesis. / Akhurst, Rosemary J.; FitzPatrick, David R.; Gatherer, Derek et al.
In: Progress in Growth Factor Research, Vol. 2, No. 3, 1990, p. 153-168.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Akhurst, RJ, FitzPatrick, DR, Gatherer, D, Lehnert, SA & Millan, FA 1990, 'Transforming growth factor betas in mammalian embryogenesis', Progress in Growth Factor Research, vol. 2, no. 3, pp. 153-168. https://doi.org/10.1016/0955-2235(90)90002-2

APA

Akhurst, R. J., FitzPatrick, D. R., Gatherer, D., Lehnert, S. A., & Millan, F. A. (1990). Transforming growth factor betas in mammalian embryogenesis. Progress in Growth Factor Research, 2(3), 153-168. https://doi.org/10.1016/0955-2235(90)90002-2

Vancouver

Akhurst RJ, FitzPatrick DR, Gatherer D, Lehnert SA, Millan FA. Transforming growth factor betas in mammalian embryogenesis. Progress in Growth Factor Research. 1990;2(3):153-168. doi: 10.1016/0955-2235(90)90002-2

Author

Akhurst, Rosemary J. ; FitzPatrick, David R. ; Gatherer, Derek et al. / Transforming growth factor betas in mammalian embryogenesis. In: Progress in Growth Factor Research. 1990 ; Vol. 2, No. 3. pp. 153-168.

Bibtex

@article{80b0651524764513a2bc3aff12467bba,
title = "Transforming growth factor betas in mammalian embryogenesis",
abstract = "Type beta transforming growth factors (TGF beta s) are members of a large superfamily of related proteins, each of which plays a pivotal role in embryonic processes. The TGF beta s per se are at least five in number, though only three isoforms have been identified in mammals. Here we will review the evidence, taken from in vitro studies on bioactivity and histochemical localization of RNAs and encoded proteins in vivo, that TGF beta 1, beta 2 and beta 3 are involved in several mammalian developmental processes, including control of growth, differentiation, tissue inductions and morphogenesis.",
keywords = "Animals, Blastocyst, Bone Development, Cardiovascular System, Embryonic and Fetal Development, Epithelium, Hematopoiesis, Transforming Growth Factor beta",
author = "Akhurst, {Rosemary J.} and FitzPatrick, {David R.} and Derek Gatherer and Lehnert, {Sigrd A.} and Millan, {Fergus A.}",
year = "1990",
doi = "10.1016/0955-2235(90)90002-2",
language = "English",
volume = "2",
pages = "153--168",
journal = "Progress in Growth Factor Research",
issn = "0955-2235",
publisher = "Pergamon Press Ltd.",
number = "3",

}

RIS

TY - JOUR

T1 - Transforming growth factor betas in mammalian embryogenesis

AU - Akhurst, Rosemary J.

AU - FitzPatrick, David R.

AU - Gatherer, Derek

AU - Lehnert, Sigrd A.

AU - Millan, Fergus A.

PY - 1990

Y1 - 1990

N2 - Type beta transforming growth factors (TGF beta s) are members of a large superfamily of related proteins, each of which plays a pivotal role in embryonic processes. The TGF beta s per se are at least five in number, though only three isoforms have been identified in mammals. Here we will review the evidence, taken from in vitro studies on bioactivity and histochemical localization of RNAs and encoded proteins in vivo, that TGF beta 1, beta 2 and beta 3 are involved in several mammalian developmental processes, including control of growth, differentiation, tissue inductions and morphogenesis.

AB - Type beta transforming growth factors (TGF beta s) are members of a large superfamily of related proteins, each of which plays a pivotal role in embryonic processes. The TGF beta s per se are at least five in number, though only three isoforms have been identified in mammals. Here we will review the evidence, taken from in vitro studies on bioactivity and histochemical localization of RNAs and encoded proteins in vivo, that TGF beta 1, beta 2 and beta 3 are involved in several mammalian developmental processes, including control of growth, differentiation, tissue inductions and morphogenesis.

KW - Animals

KW - Blastocyst

KW - Bone Development

KW - Cardiovascular System

KW - Embryonic and Fetal Development

KW - Epithelium

KW - Hematopoiesis

KW - Transforming Growth Factor beta

U2 - 10.1016/0955-2235(90)90002-2

DO - 10.1016/0955-2235(90)90002-2

M3 - Journal article

C2 - 2132953

VL - 2

SP - 153

EP - 168

JO - Progress in Growth Factor Research

JF - Progress in Growth Factor Research

SN - 0955-2235

IS - 3

ER -