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Trypanosomatid Phosphoproteomics

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Trypanosomatid Phosphoproteomics. / Urbaniak, Mick.
Protein phosphorylation in parasites: novel targets for antiparasitic intervention. ed. / Christian Doerig; Gerald Spath; Martin Wiese. Chichester: Wiley Blackwell, 2014. p. 63-78 (Drug Discovery in Infectious Diseases).

Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Chapter

Harvard

Urbaniak, M 2014, Trypanosomatid Phosphoproteomics. in C Doerig, G Spath & M Wiese (eds), Protein phosphorylation in parasites: novel targets for antiparasitic intervention. Drug Discovery in Infectious Diseases, Wiley Blackwell, Chichester, pp. 63-78. https://doi.org/10.1002/9783527675401.ch03

APA

Urbaniak, M. (2014). Trypanosomatid Phosphoproteomics. In C. Doerig, G. Spath, & M. Wiese (Eds.), Protein phosphorylation in parasites: novel targets for antiparasitic intervention (pp. 63-78). (Drug Discovery in Infectious Diseases). Wiley Blackwell. https://doi.org/10.1002/9783527675401.ch03

Vancouver

Urbaniak M. Trypanosomatid Phosphoproteomics. In Doerig C, Spath G, Wiese M, editors, Protein phosphorylation in parasites: novel targets for antiparasitic intervention. Chichester: Wiley Blackwell. 2014. p. 63-78. (Drug Discovery in Infectious Diseases). Epub 2013 Oct 11. doi: 10.1002/9783527675401.ch03

Author

Urbaniak, Mick. / Trypanosomatid Phosphoproteomics. Protein phosphorylation in parasites: novel targets for antiparasitic intervention. editor / Christian Doerig ; Gerald Spath ; Martin Wiese. Chichester : Wiley Blackwell, 2014. pp. 63-78 (Drug Discovery in Infectious Diseases).

Bibtex

@inbook{fa9fdf0d8f6042249bf347dac48b3b02,
title = "Trypanosomatid Phosphoproteomics",
abstract = "The reversible phosphorylation of serine, threonine and tyrosine plays animportant role in the biology of trypanosomatids. The identification and quantification of phosphorylation site dynamics will not only assist the elucidation of signaling pathways at the molecular level, but will also facilitate drug discovery through improved candidate selection and mode-of-action studies. Recent advances in the field of mass spectrometry-based phosphoproteomics have made the experimental observation and quantitation of thousands of phosphorylation sites feasible outside of specialist mass spectrometry laboratories. In this chapter, an introduction to phosphoproteomic techniques is presented, the current state of knowledge of the trypanosomatid phosphoproteomes is reviewed, and the potential impact of quantitative phosphoproteomics is discussed.",
author = "Mick Urbaniak",
year = "2014",
doi = "10.1002/9783527675401.ch03",
language = "English",
isbn = "9783527332359",
series = "Drug Discovery in Infectious Diseases",
publisher = "Wiley Blackwell",
pages = "63--78",
editor = "Christian Doerig and Gerald Spath and Martin Wiese",
booktitle = "Protein phosphorylation in parasites",

}

RIS

TY - CHAP

T1 - Trypanosomatid Phosphoproteomics

AU - Urbaniak, Mick

PY - 2014

Y1 - 2014

N2 - The reversible phosphorylation of serine, threonine and tyrosine plays animportant role in the biology of trypanosomatids. The identification and quantification of phosphorylation site dynamics will not only assist the elucidation of signaling pathways at the molecular level, but will also facilitate drug discovery through improved candidate selection and mode-of-action studies. Recent advances in the field of mass spectrometry-based phosphoproteomics have made the experimental observation and quantitation of thousands of phosphorylation sites feasible outside of specialist mass spectrometry laboratories. In this chapter, an introduction to phosphoproteomic techniques is presented, the current state of knowledge of the trypanosomatid phosphoproteomes is reviewed, and the potential impact of quantitative phosphoproteomics is discussed.

AB - The reversible phosphorylation of serine, threonine and tyrosine plays animportant role in the biology of trypanosomatids. The identification and quantification of phosphorylation site dynamics will not only assist the elucidation of signaling pathways at the molecular level, but will also facilitate drug discovery through improved candidate selection and mode-of-action studies. Recent advances in the field of mass spectrometry-based phosphoproteomics have made the experimental observation and quantitation of thousands of phosphorylation sites feasible outside of specialist mass spectrometry laboratories. In this chapter, an introduction to phosphoproteomic techniques is presented, the current state of knowledge of the trypanosomatid phosphoproteomes is reviewed, and the potential impact of quantitative phosphoproteomics is discussed.

U2 - 10.1002/9783527675401.ch03

DO - 10.1002/9783527675401.ch03

M3 - Chapter

SN - 9783527332359

T3 - Drug Discovery in Infectious Diseases

SP - 63

EP - 78

BT - Protein phosphorylation in parasites

A2 - Doerig, Christian

A2 - Spath, Gerald

A2 - Wiese, Martin

PB - Wiley Blackwell

CY - Chichester

ER -