TY - JOUR

T1 - When stopping the antiplatelet drugs stopped the 'TIAs'

AU - Emsley, H. C. A.

AU - Kowalewska-Zietek, J.

AU - Gulati, R. S.

AU - Wuppalapati, S.

PY - 2012/2

Y1 - 2012/2

N2 - A 70-year-old woman reported recurrent episodes of right- or left-sided sensorimotor disturbance, thought to be recurrent transient ischaemic attacks. The episodes continued despite treatment with antiplatelet agents. When MRI revealed microhaemorrhages and focal superficial cortical haemosiderin deposition, antiplatelet agents were discontinued and her transient focal neurological episodes stopped. The imaging appearances suggested cerebral amyloid angiopathy (CAA) associated with superficial siderosis—although fulfilling criteria only for ‘possible CAA’. The case highlights the diversity of transient focal neurological episodes and the difficulties in current terminology and understanding of the clinical manifestations of CAA.

AB - A 70-year-old woman reported recurrent episodes of right- or left-sided sensorimotor disturbance, thought to be recurrent transient ischaemic attacks. The episodes continued despite treatment with antiplatelet agents. When MRI revealed microhaemorrhages and focal superficial cortical haemosiderin deposition, antiplatelet agents were discontinued and her transient focal neurological episodes stopped. The imaging appearances suggested cerebral amyloid angiopathy (CAA) associated with superficial siderosis—although fulfilling criteria only for ‘possible CAA’. The case highlights the diversity of transient focal neurological episodes and the difficulties in current terminology and understanding of the clinical manifestations of CAA.

U2 - 10.1136/practneurol-2011-000035

DO - 10.1136/practneurol-2011-000035

M3 - Journal article

C2 - 22258170

AN - SCOPUS:84856015559

VL - 12

SP - 36

EP - 39

JO - Practical Neurology

JF - Practical Neurology

SN - 1474-7758

IS - 1

ER -