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WHO collaborative study to assess the suitability of an interim standard for antibodies to Ebola virus

Research output: Working paper

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WHO collaborative study to assess the suitability of an interim standard for antibodies to Ebola virus. / Wilkinson, Dianna; Page, M.; Almond, Neil et al.
Geneva: World Health Organization, 2016.

Research output: Working paper

Harvard

Wilkinson, D, Page, M, Almond, N, Anderson, R, Berry, N, Dougall, T, Efstathiou, S, Hassall, M, Mattiuzzo, G, Peter, R, Rose, N, Schepelmann, S, Stone, L, Minor, PD, Labrosse, B, Leculier, C, Pannetier, D, Strecker, T, Krahling, V, Schnierle, B, Capobianchi, M, Castilletti, C, Gatherer, D, Bishop, L, Hartman, K, Lauder, R, Wright, E, Tedder, R, Samuel, D, Dicks, S, Rudge, T, Simmons, G, Kaplan, G, Khuran, S, Weiss, CD, Hogrefe, W, Rodriguez, N, Hsu, A, Honko, AN, Bennett, RS, Pettitt, J, Janosko, K, Marchand, J, Postnikova, E, Wu, H, Griffiths, A & Hooper, JW 2016 'WHO collaborative study to assess the suitability of an interim standard for antibodies to Ebola virus' World Health Organization, Geneva. <http://apps.who.int/iris/handle/10665/197777>

APA

Wilkinson, D., Page, M., Almond, N., Anderson, R., Berry, N., Dougall, T., Efstathiou, S., Hassall, M., Mattiuzzo, G., Peter, R., Rose, N., Schepelmann, S., Stone, L., Minor, P. D., Labrosse, B., Leculier, C., Pannetier, D., Strecker, T., Krahling, V., ... Hooper, J. W. (2016). WHO collaborative study to assess the suitability of an interim standard for antibodies to Ebola virus. World Health Organization. http://apps.who.int/iris/handle/10665/197777

Vancouver

Wilkinson D, Page M, Almond N, Anderson R, Berry N, Dougall T et al. WHO collaborative study to assess the suitability of an interim standard for antibodies to Ebola virus. Geneva: World Health Organization. 2016 Jan 1.

Author

Wilkinson, Dianna ; Page, M. ; Almond, Neil et al. / WHO collaborative study to assess the suitability of an interim standard for antibodies to Ebola virus. Geneva : World Health Organization, 2016.

Bibtex

@techreport{fc7b4cbe28df495fba0ab5d1df92bdad,
title = "WHO collaborative study to assess the suitability of an interim standard for antibodies to Ebola virus",
abstract = "In support of the WHO response to the Ebola crisis, NIBSC is undertaking a project to develop an International Standard for use in the calibration and control of Ebola antibody assays. The availability of International Standards (IS) for antibodies would facilitate the standardization of Ebola serological methods used in epidemiological studies to measure past or present Ebola virus disease and in vaccinology studies to measure antibodies elicited by vaccination in humans. In the absence of such standards, individual laboratories apply their own reference standards which are not harmonized with other laboratories and methods and thus cannot serve to improve the reproducibility between laboratories. Recommendations made by participants attending the Technical Workshop on the Standardisation of Serological and PCR assays for the detection of Ebola virus (NIBSC, UK, 5-6 March 2015), included the urgent prioritization of the development of an interim Ebola standard for serology assays while perusing the longer-term goal of establishing an International Standard according to published WHO guidelines and formally endorsed by the WHO Expert Committee on Biological Standardization (ECBS). This report describes the development and worldwide collaborative study evaluation of a panel of candidate Ebola antibody preparations for the selection of the most appropriate candidate to serve as the interim WHO standard for Ebola antibody assays.",
keywords = "Ebola, diagnostics, Western blotting, ELISA, filovirus, Ebolavirus, Filoviridae",
author = "Dianna Wilkinson and M. Page and Neil Almond and Robert Anderson and Neil Berry and Thomas Dougall and Stacey Efstathiou and Mark Hassall and Giada Mattiuzzo and Rigsby Peter and N. Rose and Silke Schepelmann and Lindsay Stone and Minor, {Philip D.} and Beatrice Labrosse and Christophe Leculier and Delphine Pannetier and Thomas Strecker and Verena Krahling and Barbara Schnierle and Maria Capobianchi and Concetta Castilletti and Derek Gatherer and Lisa Bishop and Katharina Hartman and Robert Lauder and Edward Wright and Richard Tedder and Dhan Samuel and Steve Dicks and Thomas Rudge and Graham Simmons and Gerardo Kaplan and Surender Khuran and Weiss, {Carol D.} and Wayne Hogrefe and Nicole Rodriguez and Allen Hsu and Honko, {Anna N.} and Bennett, {Richard S.} and Jamie Pettitt and Krisztina Janosko and Jonathan Marchand and Elena Postnikova and Hua Wu and Anthony Griffiths and Hooper, {Jay W.}",
year = "2016",
month = jan,
day = "1",
language = "English",
volume = "WHO/BS/2015.2275Ab",
publisher = "World Health Organization",
type = "WorkingPaper",
institution = "World Health Organization",

}

RIS

TY - UNPB

T1 - WHO collaborative study to assess the suitability of an interim standard for antibodies to Ebola virus

AU - Wilkinson, Dianna

AU - Page, M.

AU - Almond, Neil

AU - Anderson, Robert

AU - Berry, Neil

AU - Dougall, Thomas

AU - Efstathiou, Stacey

AU - Hassall, Mark

AU - Mattiuzzo, Giada

AU - Peter, Rigsby

AU - Rose, N.

AU - Schepelmann, Silke

AU - Stone, Lindsay

AU - Minor, Philip D.

AU - Labrosse, Beatrice

AU - Leculier, Christophe

AU - Pannetier, Delphine

AU - Strecker, Thomas

AU - Krahling, Verena

AU - Schnierle, Barbara

AU - Capobianchi, Maria

AU - Castilletti, Concetta

AU - Gatherer, Derek

AU - Bishop, Lisa

AU - Hartman, Katharina

AU - Lauder, Robert

AU - Wright, Edward

AU - Tedder, Richard

AU - Samuel, Dhan

AU - Dicks, Steve

AU - Rudge, Thomas

AU - Simmons, Graham

AU - Kaplan, Gerardo

AU - Khuran, Surender

AU - Weiss, Carol D.

AU - Hogrefe, Wayne

AU - Rodriguez, Nicole

AU - Hsu, Allen

AU - Honko, Anna N.

AU - Bennett, Richard S.

AU - Pettitt, Jamie

AU - Janosko, Krisztina

AU - Marchand, Jonathan

AU - Postnikova, Elena

AU - Wu, Hua

AU - Griffiths, Anthony

AU - Hooper, Jay W.

PY - 2016/1/1

Y1 - 2016/1/1

N2 - In support of the WHO response to the Ebola crisis, NIBSC is undertaking a project to develop an International Standard for use in the calibration and control of Ebola antibody assays. The availability of International Standards (IS) for antibodies would facilitate the standardization of Ebola serological methods used in epidemiological studies to measure past or present Ebola virus disease and in vaccinology studies to measure antibodies elicited by vaccination in humans. In the absence of such standards, individual laboratories apply their own reference standards which are not harmonized with other laboratories and methods and thus cannot serve to improve the reproducibility between laboratories. Recommendations made by participants attending the Technical Workshop on the Standardisation of Serological and PCR assays for the detection of Ebola virus (NIBSC, UK, 5-6 March 2015), included the urgent prioritization of the development of an interim Ebola standard for serology assays while perusing the longer-term goal of establishing an International Standard according to published WHO guidelines and formally endorsed by the WHO Expert Committee on Biological Standardization (ECBS). This report describes the development and worldwide collaborative study evaluation of a panel of candidate Ebola antibody preparations for the selection of the most appropriate candidate to serve as the interim WHO standard for Ebola antibody assays.

AB - In support of the WHO response to the Ebola crisis, NIBSC is undertaking a project to develop an International Standard for use in the calibration and control of Ebola antibody assays. The availability of International Standards (IS) for antibodies would facilitate the standardization of Ebola serological methods used in epidemiological studies to measure past or present Ebola virus disease and in vaccinology studies to measure antibodies elicited by vaccination in humans. In the absence of such standards, individual laboratories apply their own reference standards which are not harmonized with other laboratories and methods and thus cannot serve to improve the reproducibility between laboratories. Recommendations made by participants attending the Technical Workshop on the Standardisation of Serological and PCR assays for the detection of Ebola virus (NIBSC, UK, 5-6 March 2015), included the urgent prioritization of the development of an interim Ebola standard for serology assays while perusing the longer-term goal of establishing an International Standard according to published WHO guidelines and formally endorsed by the WHO Expert Committee on Biological Standardization (ECBS). This report describes the development and worldwide collaborative study evaluation of a panel of candidate Ebola antibody preparations for the selection of the most appropriate candidate to serve as the interim WHO standard for Ebola antibody assays.

KW - Ebola

KW - diagnostics

KW - Western blotting

KW - ELISA

KW - filovirus

KW - Ebolavirus

KW - Filoviridae

M3 - Working paper

VL - WHO/BS/2015.2275Ab

BT - WHO collaborative study to assess the suitability of an interim standard for antibodies to Ebola virus

PB - World Health Organization

CY - Geneva

ER -