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W:Ti Flexible Transversal Electrode Array for Peripheral Nerve Stimulation: A Feasibility Study

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E-pub ahead of print
  • Carolina Silveira
  • Emma Burton
  • Enrique Escobedo-Cousin
  • Gaurav Gupta
  • Roger Whittaker
  • Anthony O'Neill
  • Kianoush Nazarpour
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<mark>Journal publication date</mark>13/08/2020
<mark>Journal</mark>IEEE Transactions on Neural Systems and Rehabilitation Engineering
Publication StatusE-pub ahead of print
Early online date13/08/20
<mark>Original language</mark>English

Abstract

The development of hardware for neural interfacing remains a technical challenge. We introduce a flexible, transversal intraneural tungsten:titanium electrode array for acute studies. We characterize the electrochemical properties of this new combination of tungsten and titanium using cyclic voltammetry and electrochemical impedance spectroscopy. With an in-vivo rodent study, we show that the stimulation of peripheral nerves with this electrode array is possible and that more than half of the electrode contacts can yield a stimulation selectivity index of 0.75 or higher at low stimulation currents. This feasibility study paves the way for the development of future cost-effective and easy-to-fabricate neural interfacing electrodes for acute settings, which ultimately can inform the development of technologies that enable bi-directional communication with the human nervous system.