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Zika virus: a previously slow pandemic spreads rapidly through the Americas

Research output: Contribution to journalJournal articlepeer-review

Published
<mark>Journal publication date</mark>1/02/2016
<mark>Journal</mark>Journal of General Virology
Issue number2
Volume97
Number of pages5
Pages (from-to)269-273
Publication StatusPublished
Early online date18/12/15
<mark>Original language</mark>English

Abstract

Zika virus (Flaviviridae) is an emerging arbovirus. Spread by Aedes mosquitoes, it was first discovered in Uganda in 1947, and later in humans elsewhere in sub-Saharan Africa, arriving in south-east Asia at latest by mid-20th-century. In the 21st century, it spread across the Pacific Islands reaching South America around 2014. Since then it has spread rapidly northwards reaching Mexico in November 2015. Its clinical profile is that of a dengue-like febrile illness, but recently associations with Guillain-Barré syndrome and microcephaly have appeared. The final geographical range and ultimate clinical impact of Zika virus are still a matter for speculation.