Accepted author manuscript, 1.41 MB, PDF document
Available under license: CC BY: Creative Commons Attribution 4.0 International License
Final published version
Research output: Contribution to Journal/Magazine › Journal article › peer-review
<mark>Journal publication date</mark> | 1/02/2016 |
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<mark>Journal</mark> | Journal of General Virology |
Issue number | 2 |
Volume | 97 |
Number of pages | 5 |
Pages (from-to) | 269-273 |
Publication Status | Published |
Early online date | 18/12/15 |
<mark>Original language</mark> | English |
Zika virus (Flaviviridae) is an emerging arbovirus. Spread by Aedes mosquitoes, it was first discovered in Uganda in 1947, and later in humans elsewhere in sub-Saharan Africa, arriving in south-east Asia at latest by mid-20th-century. In the 21st century, it spread across the Pacific Islands reaching South America around 2014. Since then it has spread rapidly northwards reaching Mexico in November 2015. Its clinical profile is that of a dengue-like febrile illness, but recently associations with Guillain-Barré syndrome and microcephaly have appeared. The final geographical range and ultimate clinical impact of Zika virus are still a matter for speculation.