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MICA: Towards using historical data for research prioritisation in children

Project: Research

Status	Finished
Effective start/end date	8/06/15 → 30/09/18

Funding

MRC: £282,824.00

Jaki, Thomas (Principal Investigator)

Research outputs

Extrapolation of efficacy and other data to support the development of new medicines for children: a systematic review of methods
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Asymmetric inner wedge group sequential tests with applications to verifying whether effective drug concentrations are similar in adults and children
Research output: Contribution to Journal/Magazine › Journal article › peer-review
A robust Bayesian meta-analytic approach to incorporate animal data into phase I oncology trials
Research output: Contribution to Journal/Magazine › Journal article › peer-review
A quantitative framework to inform extrapolation decisions in children
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Exposure–response modelling approaches for determining optimal dosing rules in children
Research output: Contribution to Journal/Magazine › Journal article › peer-review
A Bayesian decision-theoretic approach to incorporate preclinical information into phase I oncology trials
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Bridging across patient subgroups in phase I oncology trials that incorporate animal data
Research output: Contribution to Journal/Magazine › Journal article › peer-review