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Brownian dynamics simulations of iconic current through an open channel

Research output: Contribution to journalJournal article

Published

<mark>Journal publication date</mark>2005
<mark>Journal</mark>AIP Conference Proceedings
Volume780
Number of pages4
Pages563-566
Early online date25/08/05
<mark>Original language</mark>English

Abstract

Ionic motion through an open ion channel is analyzed within the framework of self‐consistent Brownian dynamics. A novel conceptual model in which the ions motion is coupled to the vibrations of the pore walls is introduced. The model allows to include into simulations an important additional mechanism of energy dissipation and the effects of self‐induced strong modulation of the channel conductivity.