We have over 12,000 students, from over 100 countries, within one of the safest campuses in the UK


97% of Lancaster students go into work or further study within six months of graduating

Home > Research > Publications & Outputs > Investigating the assumption of homogeneity of ...
View graph of relations

« Back

Investigating the assumption of homogeneity of treatment effects in clincal studies with application to meta-analysis

Research output: Contribution to journalJournal article


<mark>Journal publication date</mark>01/2012
<mark>Journal</mark>Pharmaceutical Statistics
Number of pages8
Early online date2/12/11
<mark>Original language</mark>English


An important part of the evaluation of a therapy is an investigation of the assumption of homogeneity of its effect across pre-defined subpopulations. In this paper we describe simple graphical presentations that could be used to assess the homogeneity of treatment effect and identify outliers. The emphasis in the paper is on meta-analysis but the methods described can be generalized to other investigations.