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Ion channels as electrostatic amplifiers of charge fluctuations.

Research output: Contribution to journalJournal article

Published

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Journal publication date2008
JournalJournal of Physics: Conference Series
Journal number1
Volume142
Original languageEnglish

Abstract

Electrostatic interactions between ions in an ionic channel and the charge fluctuations in the channel mouth are considered. It is shown that the charge fluctuations can be enhanced in channels of low dielectric constant, resulting in strong modulation of the potential barrier at the selectivity site. It is conjectured that similar effects can alter transition probabilities in other molecular dynamical systems.