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Ion channels as electrostatic amplifiers of charge fluctuations

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Article number012049
<mark>Journal publication date</mark>2008
<mark>Journal</mark>Journal of Physics: Conference Series
Issue number1
Volume142
Publication StatusPublished
<mark>Original language</mark>English

Abstract

Electrostatic interactions between ions in an ionic channel and the charge fluctuations in the channel mouth are considered. It is shown that the charge fluctuations can be enhanced in channels of low dielectric constant, resulting in strong modulation of the potential barrier at the selectivity site. It is conjectured that similar effects can alter transition probabilities in other molecular dynamical systems.

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“Published under licence in Journal of Physics: Conference Series by IOP Publishing Ltd. Content from this work may be used under the terms of the Creative Commons Attribution 3.0 licence. Any further distribution of this work must maintain attribution to the author(s) and the title of the work, journal citation and DOI.”