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Ionic current through an open channel : a low-dimensional model of coupling with vibrations of the wall.

Research output: Contribution in Book/Report/ProceedingsChapter

Published

Publication date2004
Host publicationFluctuations and Noise in Biological, Biophysical and Biomedical Systems II
EditorsD. Abbott, S. M. Bezrukov, A. Der, A. Sanchez
Place of publicationBellingham, Wash.
PublisherSPIE
Pages338-344
Number of pages7
Original languageEnglish

Abstract

Ionic motion through an open ion channel is analyzed within the framework of self-consistent Brownian dynamics formalism. A novel conceptual model of coupling of the ion’s motion to the vibrations of the pore walls is introduced. The model allows one to include into simulations an important additional mechanism of energy dissipation and the effects of self-induced strong modulation of the channel conductivity.

Bibliographic note

Proceedings of the Conference in Maspalomas, May 2004