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Reverse spillover of avian viral vaccine strains from domesticated poultry to wild birds

Research output: Contribution to journalJournal article

Published
<mark>Journal publication date</mark>16/06/2017
<mark>Journal</mark>Vaccine
Issue number28
Volume35
Number of pages5
Pages (from-to)3523-3527
Publication statusPublished
Early online date19/05/17
Original languageEnglish

Abstract

Transmission of viruses from the commercial poultry to wild birds is an emerging paradigm of livestock-wildlife interface. Here, we report the identification and isolation of vaccine strains of avian paramyxovirus serotype 1 (APMV1) and avian coronaviruses (ACoV) from different wild bird species across eight Egyptian governorates between January 2014 and December 2015. Surveillance of avian respiratory viruses in free-ranging wild birds (n=297) identified three species that harboured or excreted APMV1 and ACoVs. Genetic characterization and phylogenetic analysis of recovered viruses revealed a close association with the most widely utilized vaccine strains in the country. These results highlight the potential spillover of vaccine-viruses probably due to extensive use of live-attenuated vaccines in the commercial poultry, and close interaction between domesticated and wild bird populations. Further exploring the full spectrum of vaccine-derived viral vaccine strains in wild birds might help to assess the emergence of future wild-birds origin viruses.