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Results for amyloid

Publications & Outputs

  1. Clearance of interstitial fluid (ISF) and CSF (CLIC) group‐part of Vascular Professional Interest Area (PIA), updates in 2022‐2023. Cerebrovascular disease and the failure of elimination of Amyloid‐β from the brain and retina with age and Alzheimer's disease: Opportunities for therapy

    Kelly, L., Brown, C., Michalik, D., Hawkes, C. A., Aldea, R., Agarwal, N., Salib, R., Alzetani, A., Ethell, D. W., Counts, S. E., de Leon, M., Fossati, S., Koronyo‐Hamaoui, M., Piazza, F., Rich, S. A., Wolters, F. J., Snyder, H., Ismail, O., Elahi, F., Proulx, S. T., & 6 othersVerma, A., Wunderlich, H., Haack, M., Dodart, J. C., Mazer, N. & Carare, R. O., 21/02/2024, In: Alzheimer's and Dementia : the journal of the Alzheimer's Association. 20, 2, p. 1421-1435

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  2. Vascular smooth muscle cell senescence accelerates medin aggregation via small extracellular vesicle secretion and extracellular matrix reorganization

    Whitehead, M., Yusoff, S., Ahmad, S., Schmidt, L., Mayr, M., Madine, J., Middleton, D. & Shanahan, C., 28/02/2023, In: Aging Cell. 22, 2, 19 p., e13746.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  3. Knockout of apolipoprotein A-I decreases parenchymal and vascular β-amyloid pathology in the Tg2576 mouse model of Alzheimer's disease

    Contu, L., Carare, R. O. & Hawkes, C. A., 1/12/2019, In: Neuropathology and Applied Neurobiology. 45, 7, p. 698-714 17 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  4. Liposome delivery systems for the treatment of Alzheimer’s disease

    Ross, C., Taylor, M. N., Fullwood, N. J. & Allsop, D., 12/12/2018, In: International Journal of Nanomedicine. 2018, 13, p. 8507-8522 16 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  5. Epigallocatechin-3-gallate remodels apolipoprotein A-I amyloid fibrils into soluble oligomers in the presence of heparin

    Townsend, D., Hughes, E., Akien, G., Stewart, K. L., Radford, S. E., Rochester, D. & Middleton, D. A., 17/08/2018, In: Journal of Biological Chemistry. 293, 33, p. 12877-12893 17 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  6. Development of proteolytically stable N-methylated peptide inhibitors of aggregation of the amylin peptide implicated in type 2 diabetes

    Obasse, I. C., Taylor, M. N., Fullwood, N. J. & Allsop, D., 6/12/2017, In: Interface Focus. 7, 6, 11 p., 20160127.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  7. Comparisons with amyloid-β reveal an aspartate residue that stabilizes fibrils of the aortic amyloid peptide medin

    Davies, H., Madine, J. & Middleton, D., 20/03/2015, In: Journal of Biological Chemistry. 290, p. 7791-7803 13 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  8. Nanoscale SPM characterisation of nacre aragonite plates and synthetic human amyloid fibres

    Grishin, I., Tinker, C., Allsop, D., Robson, A. & Kolosov, O., 2012, NSTI-Nanotech 2012. Santa Clara, USA: CRC PRESS-TAYLOR & FRANCIS GROUP, Vol. 1. p. 110-113 4 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paperpeer-review

  9. Protein aggregation, metals and oxidative stress in neurodegenerative diseases.

    Tabner, B. J., El-Agnaf, O. M. A., German, M. J., Fullwood, N. J. & Allsop, D., 11/2005, In: Biochemical Society Transactions. 33, 5, p. 1082-1086 5 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  10. Fluorescence anisotropy: a method for early detection of Alzheimer β-peptide (Aβ) aggregation.

    Allsop, D., Swanson, L., Moore, S., Davies, Y., York, A., El-Agnaf, O. M. A. & Soutar, I., 6/07/2001, In: Biochemical and Biophysical Research Communications. 285, 1, p. 58-63 6 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review