Cheryl Hawkes - Research Portal | Lancaster University

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Dr Cheryl Hawkes

Senior Lecturer

Biomedical and Life Sciences

Furness Building

LA1 4YG

Lancaster

E-mail: Show email

ORCID: 0000-0001-9007-0130

Research Interests

My research focuses on understanding the aetiology of Alzheimer's disease (AD). In particular, I focus on the development of cerebral amyloid angiopathy (CAA), the deposition of toxic β-amyloid proteins in the walls of the blood vessels of the AD brain. I am interested in how risk factors for AD, such as ageing and obesity, affect the structure of the blood vessels and their ability to remove β-amyloid from the brain.

I am also interested in how the early life environment, including maternal and paternal obesity, impacts on the health and function of the offspring brain and if the early life environment predisposes individuals towards developing age-related diseases like AD.

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Publications & Outputs

Published
Loss of cholinergic innervation differentially affects eNOS-mediated blood flow, drainage of Aβ and cerebral amyloid angiopathy in the cortex and hippocampus of adult mice
Nizari, S., Wells, J. A., Carare, R. O., Romero, I. A. & Hawkes, C. A., 7/01/2021, In: Acta Neuropathologica Communications. 9, 1, 17 p., 12.
Research output: Contribution to journal › Journal article › peer-review
E-pub ahead of print
Age-related ultrastructural neurovascular changes in the female mouse cortex and hippocampus
Frías-Anaya, E., Gromnicova, R., Kraev, I., Rogachevsky, V., Male, D. K., Crea, F., Hawkes, C. A. & Romero, I. A., 15/12/2020, In: Neurobiology of Aging.
Research output: Contribution to journal › Journal article › peer-review
Published
Cerebrospinal fluid dynamics modulation by diet and cytokines in rats
Alimajstorovic, Z., Pascual-Baixauli, E., Hawkes, C. A., Sharrack, B., Loughlin, A. J., Romero, I. A. & Preston, J. E., 10/02/2020, In: Fluids and Barriers of the CNS. 17, 1, 10 p., 10.
Research output: Contribution to journal › Journal article › peer-review

View all (57) »

Activities

PhD viva external examiner
Activity: Examination types › Examination
International Journal of Molecular Sciences (Journal)
Activity: Publication peer-review and editorial work types › Editorial activity
PhD viva external examiner
Activity: Examination types › Examination