Cheryl Hawkes - Research Portal | Lancaster University

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Dr Cheryl Hawkes

Senior Lecturer

Biomedical and Life Sciences

Furness Building

LA1 4YG

Lancaster

E-mail: Show email

ORCID: 0000-0001-9007-0130

PhD supervision

I am happy to discuss possible MSc and PhD projects with students who are interested in brain development and ageing, factors that influence cerebrovascular health and Alzheimer's disease.

Research Interests

My research focuses on understanding the aetiology of Alzheimer's disease (AD). In particular, I focus on the development of cerebral amyloid angiopathy (CAA), the deposition of toxic β-amyloid proteins in the walls of the blood vessels of the AD brain. I am interested in how risk factors for AD, such as ageing and obesity, affect the structure of the blood vessels and their ability to remove β-amyloid from the brain.

I am also interested in how the early life environment, including maternal and paternal obesity, impacts on the health and function of the offspring brain and if the early life environment predisposes individuals towards developing age-related diseases like AD.

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Publications & Outputs

Published
Editorial: The Neurovascular Unit as a Potential Biomarker and Therapeutic Target in Cerebrovascular Disease
Nizari, S., Hawkes, C. A., Hattori, Y. & Mishra, A., 5/05/2022, In: Frontiers in Aging Neuroscience. 14, 2 p., 908716.
Research output: Contribution to Journal/Magazine › Editorial › peer-review
Published
Endothelial-derived extracellular vesicles induce cerebrovascular dysfunction in inflammation
Roig-Carles, D., Willms, E., Fontijn, R. D., Martinez-Pacheco, S., Mäger, I., de Vries, H. E., Hirst, M., Sharrack, B., Male, D. K., Hawkes, C. A. & Romero, I. A., 21/09/2021, In: Pharmaceutics. 13, 9, 1525.
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Published
The evolutionarily conserved long non-coding RNA LINC00261 drives neuroendocrine prostate cancer proliferation and metastasis via distinct nuclear and cytoplasmic mechanisms
Mather, R. L., Parolia, A., Carson, S. E., Venalainen, E., Roig-Carles, D., Jaber, M., Chu, S. C., Alborelli, I., Wu, R., Lin, D., Nabavi, N., Jachetti, E., Colombo, M. P., Xue, H., Pucci, P., Ci, X., Hawkes, C., Li, Y., Pandha, H., Ulitsky, I. & 6 others, Marconett, C., Quagliata, L., Jiang, W., Romero, I., Wang, Y. & Crea, F., 31/07/2021, In: Molecular Oncology. 15, 7, p. 1921-1941 21 p.
Research output: Contribution to Journal/Magazine › Journal article › peer-review

View all (61) »

Activities

Frontiers in Aging Neuroscience (Journal)
Activity: Publication peer-review and editorial work types › Editorial activity
PhD viva external examiner
Activity: Examination types › Examination
International Journal of Molecular Sciences (Journal)
Activity: Publication peer-review and editorial work types › Editorial activity