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Drug repurposing breakthrough: varespladib curbs snakebite-induced necrosis

Press/Media: Research

Description

News article about my PNAS dermonecrosis paper.

Period9/05/2024

News article about my PNAS dermonecrosis paper.

References

TitleDrug repurposing breakthrough: varespladib curbs snakebite-induced necrosis
Degree of recognitionInternational
Media name/outletNews Medical Life Sciences
Primary Media typeWeb
Country/TerritoryUnited Kingdom
Date9/05/24
DescriptionIn a recent study published in the journal Proceedings of the National Academy of Sciences, researchers identified venom toxins in African spitting cobras responsible for local dermonecrosis.

Snakebite is a neglected tropical disease, mainly affecting rural communities in Latin America, South Asia, Southeast Asia, and sub-Saharan Africa. An estimated 138,000 deaths occur due to snakebites annually. Severe local pathology is often observed at the bite site after viper envenoming, which results from hemorrhagic, cytotoxic, or myotoxic venom toxins. Envenoming by elapid snakes leads to neurotoxic muscle paralysis with no tissue damage.
Producer/AuthorTarun Sai Lomte
PersonsSteve Hall