Genetic diversity of 23 STR loci of the Guizhou Tujia ethnic minority and the phylogenetic relationships with 22 other populations

DOI

https://doi.org/10.6084/m9.figshare.23660553

Dataset

Shuhua Li (Creator)
Siyu Chai (Creator)
Limei Yu (Creator)
Bo-Tao Zhang (Creator)
Zulin Liu (Creator)
Yinlei Lei (Creator)
Kaiqin Chen (Creator)
Hao ZhangChanghai Hospital, Univ Victoria, University of Victoria, Dept Phys & Astron, Hubei Academy of Agricultural Sciences, Center for Brain Science, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China., Ocean University of China, Jiangsu Province Hospital, Jilin University, Nanchang University, Zhejiang Univ, Zhejiang University, Inst Informat & Commun Engn, First Affiliated Hospital of Harbin Medical University, Fudan Univ, Fudan University, Sch Informat Sci & Technol, Guangzhou & Chinese Academy of Sciences, Shandong University, Qingdao, Shandong 266237, China, Department of Cardiology, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing , China; Graduate School of Peking Union Medical College, Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing , China, Chongqing Medical University, Urology Department The Affiliated Qingdao Central Hospital of Qingdao University, The Second Affiliated Hospital of Medical College of Qingdao University Qingdao Shandong China, Univ Chinese Acad Sci, Chinese Academy of Sciences, University of Chinese Academy of Sciences, CAS, Wenzhou Medical University, The First Affiliated Hospital, Dalian Medical University, Dalian, China, Univ Arizona, University of Arizona, Cornell Univ, Cornell University, Kavli Inst Cornell, Second Affiliated Hospital of Harbin Medical University, Zhongnan Hospital of Wuhan University, Second Affiliated Hospital of Nanjing Medical University, Dalian University of Technology, Yunnan Academy of Agricultural Sciences, Guangdong University of Petrochemical Technology, College of Life Sciences, Nanjing Agricultural University, Nanjing 210095, China., Ruian People's Hospital, Henan Normal University, Guangdong Pharmaceutical University, Shanghai Jiao Tong Univ, Shanghai Jiao Tong University, Sch Mech Engn, Shanghai Children's Medical Center, Nanjing Medical University, Jiangnan University, Chinese Academy of Medical Sciences & Peking Union Medical College, South China University of Technology, Heilongjiang Provincial Hospital, McGill Univ, McGill University, McGill Sch Environm, Harvard Univ, Harvard University, Dept Phys, Nanyang Technol Univ, Nanyang Technological University, Nanyang Technological University & National Institute of Education (NIE) Singapore, Sch Mat Sci & Engn, Shanghai Stomatological Hospital, Huazhong University of Science and Technology, Jinan Univ, Jinan University, Coll Pharm, Guangdong Prov Key Lab Pharmacodynam Constituents, Arthritis Research Canada Vancouver British Columbia Canada; Department of Rehabilitation Medicine, West China Hospital Sichuan University Chengdu Sichuan China; Rehabilitation Medicine Key Laboratory of Sichuan Province, West China Hospital Sichuan University Chengdu Sichuan China, Beijing Anzhen Hospital, China agricultural University, Inner Mongolia Academy of Agricultural & Animal Husbandry Sciences, Northwestern Polytechnical University Xian (Creator)
YanFei Liu (Creator)
Pengyu Chen (Creator)

Description

Short tandem repeats (STR) are highly polymorphic DNA markers utilised in forensic personal identification and human population genetic research. Guizhou Tujia is one of the ancient minority groups in southwest China, however, the population has not been studied using the highly discriminating 23 STR Huaxia Platinum Kit. To obtain genetic data from 23 autosomal STRs in Guizhou Tujia and examine the population’s relationship with others. A total of 480 individuals from the Guizhou Tujia population were analysed using 23 STR loci of Huaxia Platinum Kit. Allele frequencies and forensic parameters were estimated. Population genetic relationships were calculated by Nei’s genetic distances and visualised using a variety of biostatistical methods. A total of 264 alleles were found, with allelic frequencies ranging from 0.0010 to 0.5104. The combined discrimination power (CDP) and the combined probability of paternity (CPE) of 23 STR loci were 0.9999999999999999999999999996 and 0.999999999710422, respectively. Guizhou Tujia showed closer genetic relationships with Hubei Tujia, Guizhou Gelao, and Guizhou Miao than with other populations. We first obtained the population genetic data of Guizhou Tujia using the 23 STR system and demonstrated its value in forensic applications. Comprehensive population comparisons showed an evident genetic affinity pattern between populations that are geographically, ethnically and linguistically related.

Date made available	2023
Publisher	Taylor & Francis

Contact person

rdm@lancaster.ac.uk

Research

DOI