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Dr Barbara Shih

Lecturer in Bioinformatics

  1. 2024
  2. Published

    Sequencing and Analysis of Lumpy Skin Disease Virus Whole Genomes Reveals a New Viral Subgroup in West and Central Africa

    Haga, I. R., Shih, B. B., Tore, G., Polo, N., Ribeca, P., Gombo-Ochir, D., Shura, G., Tserenchimed, T., Enkhbold, B., Purevtseren, D., Ulziibat, G., Damdinjav, B., Yimer, L., Bari, F. D., Gizaw, D., Adedeji, A. J., Atai, R. B., Adole, J. A., Dogonyaro, B. B., Kumarawadu, P. L., & 8 othersBatten, C., Corla, A., Freimanis, G. L., Tennakoon, C., Law, A., Lycett, S., Downing, T. & Beard, P. M., 3/04/2024, In: Viruses. 16, 4, 557.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  3. 2023
  4. Published

    Delay in loop ileostomy reversal surgery does not impact upon post-operative clinical outcomes. Complications are associated with an increased loss of microflora in the defunctioned intestine

    Beamish, E. L., Johnson, J., Shih, B., Killick, R., Dondelinger, F., McGoran, C., Brewster-Craig, C., Davies, A., Bhowmick, A. & Rigby, R. J., 31/12/2023, In: Gut Microbes. 15, 1, 2199659.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  5. Published

    Development and function of chicken XCR1 + conventional dendritic cells

    Wu, Z., Shih, B., Macdonald, J., Meunier, D., Hogan, K., Chintoan-Uta, C., Gilhooley, H., Hu, T., Beltran, M., Henderson, N. C., Sang, H. M., Stevens, M. P., McGrew, M. J. & Balic, A., 25/10/2023, In: Frontiers in Immunology. 14, 1273661.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  6. Published

    Unraveling the epidemiology of Mycobacterium bovis using whole-genome sequencing combined with environmental and demographic data

    Rossi, G., Shih, B. B. J., Egbe, N. F., Motta, P., Duchatel, F., Kelly, R. F., Ndip, L., Sander, M., Tanya, V. N., Lycett, S. J., Bronsvoort, B. M. & Muwonge, A., 17/05/2023, In: Frontiers in Veterinary Science. 10, 1086001.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  7. Published

    Defining the pig microglial transcriptome reveals its core signature, regional heterogeneity, and similarity with human and rodent microglia

    Shih, B. B., Brown, S. M., Barrington, J., Lefevre, L., Mabbott, N. A., Priller, J., Thompson, G., Lawrence, A. B. & McColl, B. W., 28/02/2023, In: Glia. 71, 2, p. 334-349 16 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  8. Published

    The developmental basis of fingerprint pattern formation and variation.

    Glover, J. D., Sudderick, ZR., Shih, BB., Batho-Samblas, C., Charlton, L., Krause, AL., Anderson, C., Riddell, J., Balic, A., Li, J., Klika, V., Woolley, TE., Gaffney, EA., Corsinotti, A., Anderson, RA., Johnston, LJ., Brown, SJ., Wang, S., Chen, Y., Crichton, M., & 1 othersHeadon, DJ., 9/02/2023, In: Cell. p. 940-956

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  9. 2022
  10. Published

    A novel strain of lumpy skin disease virus causes clinical disease in cattle in Hong Kong

    Flannery, J., Shih, B., Haga, I. R., Ashby, M., Corla, A., King, S., Freimanis, G., Polo, N., Tse, AC-N., Brackman, C. J., Chan, J., Pun, P., Ferguson, A. D., Law, A., Lycett, S., Batten, C. & Beard, P. M., 31/07/2022, In: Transboundary and Emerging Diseases. 69, 4, p. e336-e343 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  11. Published

    Graphia: A platform for the graph-based visualisation and analysis of high dimensional data

    Freeman, T. C., Horsewell, S., Patir, A., Harling-Lee, J., Regan, T., Shih, B. B., Prendergast, J., Hume, D. A. & Angus, T., 25/07/2022, In: PLoS Computational Biology. 18, 7, e1010310.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  12. Published

    Stem cell-derived porcine macrophages as a new platform for studying host-pathogen interactions

    Meek, S., Watson, T., Eory, L., McFarlane, G., Wynne, F. J., McCleary, S., Dunn, L. E. M., Charlton, E. M., Craig, C., Shih, B., Regan, T., Taylor, R., Sutherland, L., Gossner, A., Chintoan-Uta, C., Fletcher, S., Beard, P. M., Hassan, M. A., Grey, F., Hope, J. C., & 16 othersStevens, M. P., Nowak-Imialek, M., Niemann, H., Ross, P. J., Tait-Burkard, C., Brown, S. M., Lefevre, L., Thomson, G., McColl, B. W., Lawrence, A. B., Archibald, A. L., Steinbach, F., Crooke, H. R., Gao, X., Liu, P. & Burdon, T., 14/01/2022, In: BMC Biology. 20, 1, 14.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  13. 2021
  14. Published

    Mapping the human genetic architecture of COVID-19

    COVID-19 Host Genetics Initiative & Shih, B., 16/12/2021, In: Nature. 600, p. 472-477 6 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  15. Published

    Aging-Related Impairments to M Cells in Peyer’s Patches Coincide With Disturbances to Paneth Cells

    Donaldson, D. S., Shih, B. B. & Mabbott, N. A., 6/12/2021, In: Frontiers in Immunology. 12, 761949.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  16. Published

    Genetic mechanisms of critical illness in COVID-19

    Pairo-Castineira, E., Clohisey, S., Klaric, L., Bretherick, A. D., Rawlik, K., Pasko, D., Walker, S., Parkinson, N., Fourman, M. H., Russell, C. D., Furniss, J., Richmond, A., Gountouna, E., Wrobel, N., Harrison, D., Wang, B., Wu, Y., Meynert, A., Griffiths, F., Oosthuyzen, W., & 52 othersKousathanas, A., Moutsianas, L., Yang, Z., Zhai, R., Zheng, C., Grimes, G., Beale, R., Millar, J., Shih, B., Keating, S., Zechner, M., Haley, C., Porteous, D. J., Hayward, C., Yang, J., Knight, J., Summers, C., Shankar-Hari, M., Klenerman, P., Turtle, L., Ho, A., Moore, S. C., Hinds, C., Horby, P., Nichol, A., Maslove, D., Ling, L., McAuley, D., Montgomery, H., Walsh, T., Pereira, A. C., Renieri, A., GenOMICC Investigators, ISARIC4C Investigators, COVID-19 Human Genetics Initiative, 23andMe Investigators, BRACOVID Investigators, Gen-COVID Investigators, Shen, X., Ponting, C. P., Fawkes, A., Tenesa, A., Caulfield, M., Scott, R., Rowan, K., Murphy, L., Openshaw, P. J. M., Semple, M. G., Law, A., Vitart, V., Wilson, J. F. & Baillie, J. K., 4/03/2021, In: Nature. 591, 7848, p. 92-98 7 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  17. Published

    Recruitment of inflammatory monocytes by senescent fibroblasts inhibits antigen-specific tissue immunity during human aging

    Chambers, E. S., Vukmanovic-Stejic, M., Shih, B. B., Trahair, H., Subramanian, P., Devine, O. P., Glanville, J., Gilroy, D., Rustin, M. H. A., Freeman, T. C., Mabbott, N. A. & Akbar, A. N., 14/01/2021, In: Nature Aging. 1, 1, p. 101-113 13 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  18. Published

    Vitamin D3replacement enhances antigen-specific immunity in older adults

    Chambers, E. S., Vukmanovic-Stejic, M., Turner, C. T., Shih, B. B., Trahair, H., Pollara, G., Tsaliki, E., Rustin, M., Freeman, T. C., Mabbott, N. A., Noursadeghi, M., Martineau, A. R. & Akbar, A. N., 1/01/2021, In: Immunotherapy Advances. 1, 1, ltaa008.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  19. 2020
  20. Published

    Computational Analysis of SARS-CoV-2 and SARS-Like Coronavirus Diversity in Human, Bat and Pangolin Populations

    Dimonaco, N. J., Salavati, M. & Shih, B., 30/12/2020, In: Viruses. 13, 1, 49.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  21. Published

    Madin-Darby bovine kidney (MDBK) cells are a suitable cell line for the propagation and study of the bovine poxvirus lumpy skin disease virus

    Fay, P. C., Cook, C. G., Wijesiriwardana, N., Tore, G., Comtet, L., Carpentier, A., Shih, B., Freimanis, G., Haga, I. R. & Beard, P. M., 30/11/2020, In: Journal of Virological Methods. 285, 113943.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  22. Published

    Influence of skin melanisation and ultraviolet radiation on biomarkers of systemic oxidative stress

    Shih, B. B., Farrar, M. D., Vail, A., Allan, D., Chao, M-R., Hu, C-W., Jones, G. D. D., Cooke, M. S. & Rhodes, L. E., 20/11/2020, In: Free Radical Biology and Medicine. 160, p. 40-46 7 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  23. Published

    Photoprotection conferred by low level summer sunlight exposures against pro-inflammatory UVR insult

    Felton, S. J., Shih, B. B., Watson, R. E. B., Kift, R., Webb, A. R. & Rhodes, L. E., 1/06/2020, In: Photochemical and Photobiological Sciences. 19, 6, p. 810-818 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  24. Published

    Identification of Complex Rumen Microbiome Interaction Within Diverse Functional Niches as Mechanisms Affecting the Variation of Methane Emissions in Bovine

    Martínez-Álvaro, M., Auffret, M. D., Stewart, R. D., Dewhurst, R. J., Duthie, C-A., Rooke, J. A., Wallace, R. J., Shih, B., Freeman, T. C., Watson, M. & Roehe, R., 17/04/2020, In: Frontiers in Microbiology. 11, 659.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  25. 2019
  26. Published

    Visualization and analysis of RNA-Seq assembly graphs

    Nazarie, F. W., Shih, B., Angus, T., Barnett, M. W., Chen, S-H., Summers, K. M., Klein, K., Faulkner, G. J., Saini, H. K., Watson, M., Dongen, S. V., Enright, A. J. & Freeman, T. C., 22/08/2019, In: Nucleic Acids Research. 47, 14, p. 7262-7275 14 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  27. Published

    A core transcriptional signature of human microglia: Derivation and utility in describing region-dependent alterations associated with Alzheimer's disease

    Patir, A., Shih, B., McColl, B. W. & Freeman, T. C., 13/02/2019, In: Glia. 67, 7, p. 1240-1253 14 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  28. 2018
  29. Published

    Immune cell gene signatures for profiling the microenvironment of solid tumors

    Nirmal, A. J., Regan, T., Shih, B. B., Hume, D. A., Sims, A. H. & Freeman, T. C., 2/11/2018, In: Cancer Immunology Research. 6, 11, p. 1388-1400 13 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  30. Published

    Fractional Sunburn Threshold UVR Doses Generate Equivalent Vitamin D and DNA Damage in Skin Types I–VI but with Epidermal DNA Damage Gradient Correlated to Skin Darkness

    Shih, B. B., Farrar, M. D., Cooke, M. S., Osman, J., Langton, A. K., Kift, R., Webb, A. R., Berry, J. L., Watson, R. E. B., Vail, A., de Gruijl, F. R. & Rhodes, L. E., 31/10/2018, In: Journal of Investigative Dermatology. 138, 10, p. 2244-2252 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  31. 2017
  32. Published

    Derivation of marker gene signatures from human skin and their use in the interpretation of the transcriptional changes associated with dermatological disorders

    Shih, B. B., Nirmal, A. J., Headon, D. J., Akbar, A. N., Mabbott, N. A. & Freeman, T. C., 30/04/2017, In: Journal of Pathology. 241, 5, p. 600-613 14 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  33. Published

    Transforming growth factor beta gene signatures are spatially enriched in keloid tissue biopsies and ex vivo-cultured keloid fibroblasts

    Taylor, A., Budd, D. C., Shih, B., Seifert, O., Beaton, A., Wright, T., Dempsey, M., Kelly, F., Egerton, J., Marshall, R. P., Aston, N. & Bayat, A., 4/01/2017, In: Acta dermato-venereologica. 97, 1, p. 10-16 7 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

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