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Research

Dr Brian Tabner

Formerly at Lancaster University

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  1. 2014
  2. Published

    Amyloid-β fibrils in Alzheimer's Disease are not inert when bound to copper ions but can degrade hydrogen peroxide and generate reactive oxygen species

    Mayes, J., Tinker-Mill, C., Kolosov, O., Zhang, H., Tabner, B. & Allsop, D., 25/04/2014, In: Journal of Biological Chemistry. 289, p. 12052-12062 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  3. 2013
  4. Published

    A possible key role for redox-active metal ions and soluble oligomers in neurodegenerative diseases

    Tabner, B., Moore, S., Mayes, J. & Allsop, D., 2013, Brain diseases and metalloproteins. Brown, D. R. (ed.). Boca Raton, Fla.: Pan Stanford, p. 11-32 22 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Chapter

  5. 2011
  6. Published

    The amylin peptide implicated in type 2 diabetes stimulates copper-mediated carbonyl group and ascorbate radical formation

    Masad, A., Tabner, B. J., Mayes, J. & Allsop, D., 15/08/2011, In: Free Radical Biology and Medicine. 51, 4, p. 869-875 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  7. 2010
  8. Published

    Hypothesis: soluble Aβ oligomers in association with redox-active metal ions are the optimal generators of reactive oxygen species in Alzheimer's disease

    Tabner, B. J., Mayes, J. & Allsop, D., 8/10/2010, In: International Journal of Alzheimer's Disease. 2011, 6 p., 546380.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  9. 2008
  10. Published

    Metal-dependent generation of reactive oxygen species from amyloid proteins implicated in neurodegenerative disease

    Allsop, D., Mayes, J., Moore, S., Masad, A. & Tabner, B. J., 2008, In: Biochemical Society Transactions. 36, 6, p. 1293-1298 6 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  11. 2007
  12. Published

    Copper-mediated formation of hydrogen peroxide from the amylin peptide: a novel mechanism for degeneration of islet cells in type-2 diabetes mellitus?

    Masad, A., Hayes, L., Tabner, B., Turnbull, S., Cooper, L., Fullwood, N. J., German, M., Kametani, F., El-Agnaf, O. M. A. & Allsop, D., 2007, In: FEBS Letters. 581, 18, p. 3489-3493 5 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  13. 2006
  14. Published

    A spectroscopic study of some of the peptidyl radicals formed following hydroxyl radical attack on β-amyloid and α-synuclein.

    Tabner, B. J., Turnbull, S., King, J., Benson, F. E., El-Agnaf, O. M. A. & Allsop, D., 07/2006, In: Free Radical Research. 40, 7, p. 731-739 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  15. 2005
  16. Published

    Protein aggregation, metals and oxidative stress in neurodegenerative diseases.

    Tabner, B. J., El-Agnaf, O. M. A., German, M. J., Fullwood, N. J. & Allsop, D., 11/2005, In: Biochemical Society Transactions. 33, 5, p. 1082-1086 5 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  17. Published

    Hydrogen peroxide is generated during the very early stages of aggregation of the amyloid peptides implicated in Alzheimer's disease and familial British dementia.

    Tabner, B. J., El-Agnaf, O. M. A., Turnbull, S., German, M. J., Paleologou, K. E., Hayashi, Y., Cooper, L. J., Fullwood, N. & Allsop, D., 28/10/2005, In: Journal of Biological Chemistry. 280, 43, p. 35789-35792 4 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  18. Published

    The production of hydrogen peroxide during early-stage protein aggregation: a common pathological mechanism in different neurodegenerative diseases?

    Tabner, B., Turnbull, S., Fullwood, N. J., German, M. & Allsop, D., 08/2005, In: Biochemical Society Transactions. 33, 4, p. 548-550 3 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  19. 2004
  20. Published

    Both the D-(+) and L-(-) enantiomers of nicotine inhibit Aβ aggregation and cytotoxicity.

    Moore, S. A., Huckerby, T. N., Gibson, G. L., Fullwood, N. J., Turnbull, I., Tabner, B. J., El-Agnaf, O. M. A. & Allsop, D., 01/2004, In: Biochemistry. 43, 3, p. 819-826 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  21. 2003
  22. Published

    Quinacrine acts as an antioxidant and reduces the toxicity of the prion peptide PrP106-126.

    Turnbull, S., Tabner, B. J., Brown, D. R. & Allsop, D., 15/09/2003, In: NeuroReport. 14, 13, p. 1743-1745 3 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  23. Published

    Generation of hydrogen peroxide from mutant forms of the prion protein fragment PrP121-231.

    Turnbull, S., Tabner, B. J., Brown, D. R. & Allsop, D., 1/07/2003, In: Biochemistry. 42, 25, p. 7675-7681 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  24. Published

    Copper-dependent generation of hydrogen peroxide from the toxic prion protein fragment PrP106-126.

    Turnbull, S., Tabner, B. J., Brown, D. R. & Allsop, D., 23/01/2003, In: Neuroscience Letters. 336, 3, p. 159-162 4 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  25. Published

    Direct production of reactive oxygen species from aggregating proteins and peptides implicated in the pathogenesis of neurodegenerative diseases.

    Tabner, B. J., Turnbull, S., El-Agnaf, O. M. A. & Allsop, D., 2003, In: Current Medicinal Chemistry Immunology Endocrine and Metabolic Agents. 3, 4, p. 299-308 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  26. 2002
  27. Published

    Formation of hydrogen peroxide and hydroxyl radicals from Aβ and α-synuclein as a possible mechanism of cell death in Alzheimer’s disease and Parkinson’s disease.

    Tabner, B. J., Turnbull, S., El-Agnaf, O. M. A. & Allsop, D., 1/06/2002, In: Free Radical Biology and Medicine. 32, 11, p. 1076-1083 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  28. 2001
  29. Published

    Synthesis of poly(isobutylene-b-styrene) block copolymers by thermolysis of ozonised alkene-ended polyisobutylenes in the presence of styrene.

    Cunliffe, D., Lockley, J. E., Ebdon, J. R., Rimmer, S. & Tabner, B. J., 5/06/2001, In: Macromolecules. 34, 12, p. 3882-3888 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  30. Published

    New evidence that the Alzheimer β-amyloid peptide does not spontaneously form free radicals: An ESR study using a series of spin-traps.

    Turnbull, S., Tabner, B. J., El-Agnaf, O. M. A., Twyman, L. J. & Allsop, D., 15/05/2001, In: Free Radical Biology and Medicine. 30, 10, p. 1154-1162 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  31. Published

    α-synuclein implicated in Parkinson’s disease catalyses the formation of hydrogen peroxide in vitro.

    Turnbull, S., Tabner, B. J., Moore, S., Davies, Y., El-Agnaf, O. M. A. & Allsop, D., 15/05/2001, In: Free Radical Biology and Medicine. 30, 10, p. 1163-1170 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  32. Published

    Polymerisation of methyl methacrylate initiated by ozonates of Tetramethylethene.

    Lockley, J. E., Ebdon, J. R., Rimmer, S. & Tabner, B. J., 03/2001, In: Polymer. 42, 5, p. 1797-1807 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  33. Published

    ESR spin-trap study of the radicals present during the thermolysis of some novel dialkyl peroxides.

    Mekarbane, P. G. & Tabner, B. J., 01/2001, In: Magnetic Resonance in Chemistry. 39, 1, p. 9-14 6 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  34. Published

    Production of reactive oxygen species from aggregating proteins implicated in Alzheimer's disease, Parkinson's disease and other neurodegenerative diseases.

    Tabner, B. J., Turnbull, S., El-Agnaf, O. M. A. & Allsop, D., 2001, In: Current Topics in Medicinal Chemistry. 1, p. 483-493 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  35. 2000
  36. Published

    ESR spin-trap study of the radicals present during the thermolysis of some novel alkyl peroxy esters.

    Mekarbane, P. G. & Tabner, B. J., 10/2000, In: Magnetic Resonance in Chemistry. 38, 10, p. 845-852 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  37. Published

    Cyclic diperoxides as sources of radicals for the initiation of the radical polymerisation of methyl methacrylate.

    Lockley, J. E., Ebdon, J. R., Rimmer, S. & Tabner, B. J., 08/2000, In: Macromolecular Rapid Communications. 21, 12, p. 841-845 5 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  38. Published

    ESR spin-trap study of the radicals present during the thermolysis of some bis(tert-alkylperoxy)alkanes and bis(tert-alkylperoxy)cycloalkanes.

    Mekarbane, P. G. & Tabner, B. J., 03/2000, In: Magnetic Resonance in Chemistry. 38, 3, p. 183-191 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  39. Published

    An EPR spin-trap study of the radicals present during the thermolysis of some novel monoperoxycarbonates and peroxydicarbonates.

    Mekarbane, P. G. & Tabner, B. J., 2000, In: Journal of the Chemical Society- Perkin Transactions. 2, p. 1465-1470 6 p.

    Research output: Contribution to Journal/Magazine › Journal article

  40. Published

    Quaternary environmental change in Cyrenaica evidenced by U-Th, ESR and OSL dating of coastal alluvial fan sequences.

    Rowan, J. S., Black, S., Macklin, M. G., Tabner, B. J. & Dore, J., 2000, In: Libyan Studies. 31, p. 5-16 12 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  41. 1999
  42. Published

    ESR dating of quartz phenocrysts in some rhyolitic extrusive rocks using A1 and Ti impurity centres.

    Wild, M., Tabner, B. J. & Macdonald, R., 11/1999, In: Quaternary Science Reviews. 18, 13, p. 1507-1514 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  43. Published

    The interaction between radicals derived from two di-t-alkyl peroxides with some monomers and polymers.

    Mekarbane, P. G. & Tabner, B. J., 1/06/1999, In: Macromolecules. 32, 11, p. 3620-3625 6 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  44. Published

    Soluble iron sulfide species in natural waters: reappraisal of their stoichiometry and stability constants.

    Davison, W., Phillips, N. & Tabner, B. J., 01/1999, In: Aquatic Sciences - Research Across Boundaries . 61, 1, p. 23-43 21 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  45. 1998
  46. Published

    An ESR spin-trap study of radicals present during the thermolysis of some di-t-alkyl peroxides.

    Mekabane, P. G. & Tabner, B. J., 11/1998, In: Magnetic Resonance in Chemistry. 36, 11, p. 826-832 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  47. 1997
  48. Published

    Depositional time trends and remobilisation of PCBs in lake sediments.

    Gevao, B., Hamilton-Taylor, J., Murdoch, C., Jones, K. C., Kelly, M. & Tabner, B. J., 11/1997, In: Environmental Science and Technology. 31, 11, p. 3274-3280 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  49. Published

    Radical concentrations and reaction temperature profiles during the (batch) core-shell emulsion polymerisation of methyl methacrylate and butyl acrylate, studied by electron spin resonance spectroscopy.

    Cutting, G. R. & Tabner, B. J., 02/1997, In: European Polymer Journal. 33, 2, p. 213-217 5 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  50. 1996
  51. Published

    Stable radicals observed in the flesh of irradiated citrus fruits by electron spin resonance spectroscopy for the first time.

    Tabner, B. J. & Tabner, V. A., 1996, In: Radiation Physics and Chemistry. 47, 4, p. 601-605 5 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  52. 1995
  53. Published

    Reaction temperature profiles and radical concentration measurements on batch emulsion copolymerizations of methyl-methacrylate and butyl acrylate.

    Cutting, G. R. & Tabner, B. J., 12/1995, In: European Polymer Journal. 31, 12, p. 1215-1219 5 p.

    Research output: Contribution to Journal/Magazine › Journal article

  54. 1994
  55. Published

    A high-field 13C-NMR study of the aqueous copolymerisations of acrylonitrile and vinyl acetate. Microstructural observations.

    Cheetham, P. F. & Tabner, B. J., 12/1994, In: European Polymer Journal. 30, 12, p. 1367-1373 7 p.

    Research output: Contribution to Journal/Magazine › Journal article

  56. Published

    A high-field 13C-NMR study of the aqueous copolymerizations of acrylonitrile and vinyl acetate. Determination of comonomer reactivity ratios.

    Cheetham, P. F., Huckerby, T. N. & Tabner, B. J., 1994, In: European Polymer Journal. 30, 5, p. 581-587 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  57. Published

    Electron spin resonance spectra of γ-irradiated citrus fruit skins, skin components and stalks.

    Tabner, B. J. & Tabner, V. A., 1994, In: International Journal of Food Science and Technology. 29, 2, p. 143-152 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  58. Published

    The determination of hydroxyl radical concentrations in environmental chambers using electron spin resonance.

    Stokes, N. J., Tabner, B. J. & Hewitt, C., 1994, In: Chemosphere. 28, 5, p. 999-1008 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  59. Published

    The effects of reactive hydrocarbons on plants.

    Stokes, N. J., Terry, G., Tabner, B. J. & Hewitt, C., 1994, In: Proceedings of the Royal Society of Edinburgh. Section B: Biology. 102, p. 307-311 5 p.

    Research output: Contribution to Journal/Magazine › Journal article

  60. 1993
  61. Published

    Radical termination and radical concentrations during the batch emulsion polymerization of methyl methacrylate studied by electron spin resonance spectroscopy.

    Cutting, G. R. & Tabner, B. J., 09/1993, In: Macromolecules. 26, 5, p. 951-955 5 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  62. Published

    A spin-trap study of the aqueous heterogeneous copolymerization of acrylonitrile and vinyl acetate.

    Cheetham, P. F. & Tabner, B. J., 1993, In: European Polymer Journal. 29, 2-3, p. 451-454 4 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  63. Published

    An electron spin resonance study of gamma-irradiated citrus fruits.

    Tabner, V. A. & Tabner, B. J., 1993, In: International Journal of Radiation Applications and Instrumentation. Part C, Radiation Physics and Chemistry. 41, 3, p. 545-552 8 p.

    Research output: Contribution to Journal/Magazine › Journal article

  64. 1992
  65. Published

    A spin-trap study of the copolymerization of styrene and vinyl acetate - additional comments.

    O'Driscoll, K. F. & Tabner, B. J., 04/1992, In: European Polymer Journal. 28, 4, p. 333-333 1 p.

    Research output: Contribution to Journal/Magazine › Journal article

  66. Published

    Spin-trapping artifacts on addition of polyacrylonitrile and poly(methyl methacrylate) to dimethyl sulphoxide.

    Cheetham, P. F., Cutting, G. R. & Tabner, B. J., 1992, In: Magnetic Resonance in Chemistry. 30, 7, p. 626-631 6 p.

    Research output: Contribution to Journal/Magazine › Journal article

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