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Research

Dr Brian Tabner

Formerly at Lancaster University

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  1. 2014
  2. Published

    Amyloid-β fibrils in Alzheimer's Disease are not inert when bound to copper ions but can degrade hydrogen peroxide and generate reactive oxygen species

    Mayes, J., Tinker-Mill, C., Kolosov, O., Zhang, H., Tabner, B. & Allsop, D., 25/04/2014, In: Journal of Biological Chemistry. 289, p. 12052-12062 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  3. 2013
  4. Published

    A possible key role for redox-active metal ions and soluble oligomers in neurodegenerative diseases

    Tabner, B., Moore, S., Mayes, J. & Allsop, D., 2013, Brain diseases and metalloproteins. Brown, D. R. (ed.). Boca Raton, Fla.: Pan Stanford, p. 11-32 22 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Chapter

  5. 2011
  6. Published

    The amylin peptide implicated in type 2 diabetes stimulates copper-mediated carbonyl group and ascorbate radical formation

    Masad, A., Tabner, B. J., Mayes, J. & Allsop, D., 15/08/2011, In: Free Radical Biology and Medicine. 51, 4, p. 869-875 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  7. 2010
  8. Published

    Hypothesis: soluble Aβ oligomers in association with redox-active metal ions are the optimal generators of reactive oxygen species in Alzheimer's disease

    Tabner, B. J., Mayes, J. & Allsop, D., 8/10/2010, In: International Journal of Alzheimer's Disease. 2011, 6 p., 546380.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  9. 2008
  10. Published

    Metal-dependent generation of reactive oxygen species from amyloid proteins implicated in neurodegenerative disease

    Allsop, D., Mayes, J., Moore, S., Masad, A. & Tabner, B. J., 2008, In: Biochemical Society Transactions. 36, 6, p. 1293-1298 6 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  11. 2007
  12. Published

    Copper-mediated formation of hydrogen peroxide from the amylin peptide: a novel mechanism for degeneration of islet cells in type-2 diabetes mellitus?

    Masad, A., Hayes, L., Tabner, B., Turnbull, S., Cooper, L., Fullwood, N. J., German, M., Kametani, F., El-Agnaf, O. M. A. & Allsop, D., 2007, In: FEBS Letters. 581, 18, p. 3489-3493 5 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  13. 2006
  14. Published

    A spectroscopic study of some of the peptidyl radicals formed following hydroxyl radical attack on β-amyloid and α-synuclein.

    Tabner, B. J., Turnbull, S., King, J., Benson, F. E., El-Agnaf, O. M. A. & Allsop, D., 07/2006, In: Free Radical Research. 40, 7, p. 731-739 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  15. 2005
  16. Published

    Protein aggregation, metals and oxidative stress in neurodegenerative diseases.

    Tabner, B. J., El-Agnaf, O. M. A., German, M. J., Fullwood, N. J. & Allsop, D., 11/2005, In: Biochemical Society Transactions. 33, 5, p. 1082-1086 5 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  17. Published

    Hydrogen peroxide is generated during the very early stages of aggregation of the amyloid peptides implicated in Alzheimer's disease and familial British dementia.

    Tabner, B. J., El-Agnaf, O. M. A., Turnbull, S., German, M. J., Paleologou, K. E., Hayashi, Y., Cooper, L. J., Fullwood, N. & Allsop, D., 28/10/2005, In: Journal of Biological Chemistry. 280, 43, p. 35789-35792 4 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  18. Published

    The production of hydrogen peroxide during early-stage protein aggregation: a common pathological mechanism in different neurodegenerative diseases?

    Tabner, B., Turnbull, S., Fullwood, N. J., German, M. & Allsop, D., 08/2005, In: Biochemical Society Transactions. 33, 4, p. 548-550 3 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

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