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Dr Christopher Gaffney

Senior Lecturer in Integrative Physiology

  1. Published

    Crash diets may work against you - and could have permanent consequences

    Gaffney, C., 2/01/2024

    Research output: Exhibits, objects and web-based outputsBlog

  2. Published

    Muscle strength deficiency and mitochondrial dysfunction in a muscular dystrophy model of C. elegans and its functional response to drugs

    Hewitt, J., Pollard, A., Lesanpezeshki, L., Deane, C., Gaffney, C. J., Etheridge, T., Szewczyk, N. & Vanapalli, S., 31/12/2018, In: Disease Models & Mechanisms. 11, 11, 13 p., 36137.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  3. Published

    Cancer: getting in shape before surgery can shorten hospital stays

    Keegan, T. & Gaffney, C., 16/09/2021

    Research output: Exhibits, objects and web-based outputsWeb publication/site

  4. Published

    Laparoscopic skills Acquisition in obstetrics and Gynaecology and General Surgical trainees (LAGGS)

    Khan, Z., Shrestha, D., Shugaba, A., Gaffney, C., Afors, K., Clark, J. & Subar, D., 21/04/2022.

    Research output: Contribution to conference - Without ISBN/ISSN Abstractpeer-review

  5. Forthcoming

    Comparing proficiency of obstetrics and gynaecology trainees with general surgery trainees using simulated laparoscopic tasks in Health Education England, North-West: a prospective observational study

    Khan, Z., Shrestha, D., Shugaba, A., Lambert, J., Clark, J., Haslett, E., Afors, K., Bampouras, T., Gaffney, C. & Subar, D., 23/10/2023, (Accepted/In press) In: BMJ Open.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  6. Published

    Comparative Analysis of Muscle Atrophy During Spaceflight, Nutritional Deficiency and Disuse in the Nematode Caenorhabditis elegans

    Kim, B., Alcantara, A., Moon, J-H., Higashitani, A., Higashitani, N., Etheridge, T., Szewczyk, N. J., Deane, C., Gaffney, C., Higashibata, A., Hashizume, T., Yoon, K. & Lee, J., 10/08/2023, In: International Journal of Molecular Sciences. 24, 16, 12640.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  7. E-pub ahead of print

    The impact of prehabilitation on patient outcomes in hepatobiliary, colorectal, and upper gastrointestinal cancer surgery: a PRISMA-accordant meta-analysis

    Lambert, J., Hayes, L., Keegan, T., Subar, D. & Gaffney, C., 12/11/2020, (E-pub ahead of print) In: Annals of Surgery. 0, p. 0-0

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  8. Published

    Response to: (Comment on “The impact of prehabilitation on patient outcomes in hepatobiliary, colorectal and Upper Gastro-intestinal cancer surgery: A PRISMA-Accordant Meta-Analysis”)

    Lambert, J., Hayes, L., Keegan, T., Subar, D. & Gaffney, C., 31/12/2021, In: Annals of Surgery. 274, 6, p. e932-e933 2 p.

    Research output: Contribution to Journal/MagazineLetterpeer-review

  9. Published

    Response to “Comment on Prehabilitation in Major Abdominal Surgery”

    Lambert, J., Hayes, L., Keegan, T., Subar, D. & Gaffney, C., 31/12/2021, In: Annals of Surgery. 274, 6, p. e944-e945 2 p.

    Research output: Contribution to Journal/MagazineLetterpeer-review

  10. Published

    Response to the Comment on "the Impact of Prehabilitation on Patient Outcomes in Hepatobiliary, Colorectal, and Upper Gastro-intestinal Cancer Surgery: A PRISMA-Accordant Meta-analysis"

    Lambert, J., Hayes, L., Keegan, T., Subar, D. & Gaffney, C., 1/12/2021, In: Annals of Surgery. 274, 6, p. e946-e947 2 p.

    Research output: Contribution to Journal/MagazineLetterpeer-review

  11. Published
  12. Published

    The Effect of the Enhanced Recovery Programme on long term survival following liver resection for colorectal liver metastases

    Lambert, J., Mair, T., Arunjunan, K., Shugaba, A., Uwadiae, H., Livesey, A., Ahmad, R., Sgourakis, G., Gaffney, C. & Subar, D., 31/12/2023, In: Langenbeck's Archives of Surgery . 408, 1, 239.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  13. Published

    Spaceflight Affects Neuronal Morphology and Alters Transcellular Degradation of Neuronal Debris in Adult Caenorhabditis elegans

    Laranjeiro, R., Harinath, G., Pollard, A. K., Gaffney, C., Deane, C., Vanapalli, S., Etheridge, T., Szewczyk, N. J. & Driscoll, M., 19/02/2021, In: iScience. 24, 2, 36 p., 102105.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  14. Published

    Glutathione reductase gsr-1 is an essential gene required for Caenorhabditis elegans early embryonic development

    Mora-Lorca, J. A., Sáenz-Narciso, B., Gaffney, C. J., Naranjo-Galindo, F. J., Pedrajas, J. R., Guerrero-Gómez, D., Dobrzynska, A., Askjaer, P., Szewczyk, N. J., Cabello, J. & Miranda-Vizuete, A., 07/2016, In: Free Radical Biology and Medicine. 96, p. 446-461 16 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  15. Published

    Protective role of DNJ-27/ERdj5 in Caenorhabditis elegans models of human neurodegenerative diseases

    Muñoz-Lobato, F., Rodríguez-Palero, M. J., Naranjo-Galindo, F. J., Shephard, F., Gaffney, C. J., Szewczyk, N. J., Hamamichi, S., Caldwell, K. A., Caldwell, G. A., Link, C. D. & Miranda-Vizuete, A., 10/01/2014, In: Antioxidants and Redox Signaling. 20, 2, p. 217-235 19 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  16. Published

    Gene therapy-mediated enhancement of protective protein expression for the treatment of Alzheimer's disease

    Owens, L., Benedetto, A., Dawson, N., Gaffney, C. & Parkin, E., 15/02/2021, In: Brain Research. 1753, 12 p., 147264.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  17. Published

    BACE1 Overexpression Reduces SH-SY5Y Cell Viability Through a Mechanism Distinct from Amyloid-β Peptide Accumulation: Beta Prime-Mediated Competitive Depletion of sAβPPα

    Owens, L., Bracewell, J., Benedetto, A., Dawson, N., Gaffney, C. & Parkin, E., 5/04/2022, In: Journal of Alzheimer's Disease. 86, 3, p. 1201-1220 20 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  18. Published

    C. elegans as a model for understanding spaceflight induced muscle decline

    Pollard, A., Gaffney, C., Deane, C., Cooke, M., Hewitt, J., Phillips, B., Szewczyk, N., Vanapalli, S. & Etheridge, T., 18/06/2018.

    Research output: Contribution to conference - Without ISBN/ISSN Abstractpeer-review

  19. Published

    Molecular Muscle Experiment: Hardware and Operational Lessons for Future Astrobiology Space Experiments

    Pollard, A., Gaffney, C., Deane, C., Balsamo, M., Cooke, M., Ellwood, R., Hewitt, J., Mierzwa, B., Mariani, A., Vanapalli, S. A., Etheridge, T. & Szewczyk, N. J., 6/08/2020, In: Astrobiology. 20, 8, p. 935-943 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  20. Published

    EXPLORING DIFFERENCES IN ELECTROMYOGRAPHY AND GROUND REACTION FORCES BETWEEN FRONT AND BACK SQUATS BEFORE AND AFTER A FATIGUING PROTOCOL

    Rattley, C., Gaffney, C. & Bampouras, T., 23/07/2022, ISBS Proceedings Archive. International Society of Biomechanics in Sports, 5 p. 138. (ISBS Proceedings Archive; vol. 40, no. 1).

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNAbstract

  21. Published

    FGF21 Is an Insulin-Dependent Postprandial Hormone in Adult Humans

    Samms, R. J., Lewis, J. E., Norton, L., Stephens, F. B., Gaffney, C. J., Butterfield, T., Smith, D. P., Cheng, C. C., Perfield, J. W., Adams, A. C., Ebling, F. J. P. & Tsintzas, K., 1/10/2017, In: Journal of Clinical Endocrinology and Metabolism. 102, 10, p. 3806-3813 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  22. Published

    Should all minimal access surgery be robot-assisted? A systematic review into the musculoskeletal and cognitive demands of laparoscopic and robot-assisted laparoscopic surgery

    Shugaba, A., Lambert, J., Bampouras, T., Nuttall, H. E., Gaffney, C. & Subar, D., 31/07/2022, In: Journal of Gastrointestinal Surgery. 26, 7, p. 1520-1530 11 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  23. Published

    MUSCLE ACTIVITY ASSOCIATED WITH PERFORMING ROBOT- ASSISTED AND CONVENTIONAL LAPAROSCOPY

    Shugaba, A., Lambert, J., Nuttall, H. E., Subar, D., Gaffney, C. & Bampouras, T., 29/06/2022.

    Research output: Contribution to conference - Without ISBN/ISSN Abstractpeer-review

  24. Forthcoming

    Surgical stress: the muscle and cognitive demands of robotic and laparoscopic surgery

    Shugaba, A., Subar, D., Slade, K., Willett, M., Abdel-Aty, M., Campbell, I., Heywood, N., Vitone, L., Sheikh, A., Gill, M., Zelhof, B., Nuttall, H. E., Bampouras, T. & Gaffney, C., 30/03/2023, (Accepted/In press) In: Annals of Surgery - Open.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  25. E-pub ahead of print

    Effect of acute and short-term dietary fat ingestion on postprandial skeletal muscle protein synthesis rates in middle-aged, overweight and obese men

    Tsintzas, K., Jones, R., Pabla, P., Mallinson, J., Barrett, D., Kim, D-H., Cooper, S., Davies, A., Taylor, T., Gaffney, C., Chee, C., van Loon, L. & Stephens, F., 7/01/2020, (E-pub ahead of print) In: American Journal of Physiology - Endocrinology and Metabolism.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

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