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Research

Professor David Allsop

Formerly at Lancaster University

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  1. Published

    High affinity amyloid peptide β/A4 binding sites and a putative "APP secretase" in rat brain

    Allsop, D., Yamamoto, T., Kametani, F., Miyazaki, N. & Ishii, T., 1991, Proceedings of the XIth International Congress of Neuropathology: The Japanese Society of Neuropathology. Sasaki, Japan, p. 119-127 9 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Conference contribution/Paper › peer-review

  2. Published

    Secretory derivatives of Alzheimer amyloid precursor protein in cerebrospinal fluid and brain: only Kunitz-containing forms show amyloid immunoreactivity

    Allsop, D., Kennedy, H. E. & Kametani, F., 1993, Alzheimer's disease: advances in clinical and basic research. Corain, B., Iqbal, K., Nicolini, M., Winblad, B., Wisniewski, H. M. & Zatta, P. (eds.). Chichester: Wiley, p. 421-429 9 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Conference contribution/Paper › peer-review

  3. Published

    Mechanism of cerebral amyloidosis in Alzheimer's disease

    Allsop, D., Clements, A., Kennedy, H. E., Walsh, D. M. & Williams, C. H., 1994, Amyloid precursor protein in development, ageing and Alzheimer's disease. Berlin: Springer Verlag, p. 46-59 14 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Conference contribution/Paper › peer-review

  4. Published

    Studies on inhibition of β-amyloid formation in APP-751-transfected IMR-32 cells, and SPA4CT-transfected SHSY5Y cells

    Allsop, D., Christie, G., Gray, C., Holmes, S., Markwell, R., Owen, D., Smith, L., Wadsworth, H., Ward, R. V., Hartmann, T., Lichtenthaler, S. F., Evin, G., Fuller, S., Tanner, J., Masters, C. L., Beyreuther, K. & Roberts, G. W., 1997, Alzheimer's disease: biology, diagnosis and therapeutics. Iqbal, K., Winblad, B., Nishimura, T., Takeda, M. & Wisniewski, H. M. (eds.). New York: Wiley, p. 717-727 11 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Conference contribution/Paper › peer-review

  5. Published

    Modulation of β-amyloid production and fibrillisation

    Allsop, D., Twyman, L., Davies, Y., Moore, S., York, A., Swanson, L. & Soutar, I., 2000, In: Biochemical Society Symposia. 67, p. 1-14 14 p.

    Research output: Contribution to Journal/Magazine › Literature review › peer-review

  6. Published

    Amyloid β-peptide and Alzheimer's disease

    Allsop, D. & Mayes, J., 18/08/2014, In: Essays in Biochemistry. 56, p. 99-110 12 p., 7.

    Research output: Contribution to Journal/Magazine › Literature review › peer-review

  7. Published

    A novel approach to the therapy of Alzheimer's disease based on peptide nanoliposome inhibitors of Aβ and tau aggregation

    Allsop, D., Taylor, M. N., Fullwood, N. J., Michael, M., Aggidis, A., Vincent, S. & Dale, M., 1/11/2017, In: Journal of Prevention of Alzheimer's Disease. 4, 4, p. 385-386 2 p.

    Research output: Contribution to Journal/Magazine › Meeting abstract › peer-review

  8. Published

    Untangled - peptide-based inhibitors of tau aggregation as a potential treatment for Alzheimer's disease

    Allsop, D., Aggidis, A., Fullwood, N. J., Taylor, M. N., Foulds, P., Vincent, S. & Dale, M., 2018, In: Journal of Prevention of Alzheimer's Disease. 5, Suppl 1, p. S15-S16 2 p.

    Research output: Contribution to Journal/Magazine › Meeting abstract

  9. Published

    Chloroplast development in normal and mutant lines of barley

    Atkinson, Y. E., Allsop, D. & Bradbeer, J. W., 1981, Photosynthesis V: chloroplast development. Akoyunoglou, G. (ed.). Philadelphia: Balaban International Science Services, p. 797-808 12 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Conference contribution/Paper › peer-review

  10. Published

    Designing peptide inhibitors for oligomerization and toxicity of Alzheimer's β-amyloid peptide

    Austen, B. M., Paleologou, K. E., Ali, S. A. E., Qureshi, M. M., Allsop, D. & El-Agnaf, O. M. A., 2008, In: Biochemistry. 47, 7, p. 1984-1992 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  11. Published

    Self-Assembly and Anti-Amyloid Cytotoxicity Activity of Amyloid beta Peptide Derivatives

    Castelletto, V., Ryumin, P., Cramer, R., Hamley, I., Taylor, M. N., Allsop, D., Reza, M., Ruokolainen, J., Arnold, T., Hermida-Merino, D., Garcia, C. I., Leal, M. C. & Castaño, E., 8/03/2017, In: Scientific Reports. 7, 12 p., 43637.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  12. Published

    Alzheimer's Disease: correlation of the suppression of β-Amyloid peptide secretion from cultured cells with inhibition of the chymotrypsin-like activity of the proteasome

    Christie, G., Markwell, R. E., Gray, C. W., Smith, L., Godfrey, F., Mansfield, F., Wadsworth, H., King, R., McLaughlin, M., Cooper, D. G., Ward, R. V., Howlett, D. R., Hartmann, T., Lichtenthaler, S. F., Beyreuther, K., Underwood, J., Gribble, S. K., Cappai, R., Masters, C. L., Tamaoka, A., & 4 othersGardner, R. L., Rivett, A. J., Karran, E. H. & Allsop, D., 07/1999, In: Journal of Neurochemistry. 73, 1, p. 195-204 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  13. Published

    Aggregation and metal-binding properties of mutant forms of the amyloid Aβ peptide of Alzheimer's disease

    Clements, A., Allsop, D., Walsh, D. M. & Williams, C. H., 02/1996, In: Journal of Neurochemistry. 66, 2, p. 740-747 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  14. Published

    Aggregation of Alzheimer's peptides

    Clements, A., Walsh, D. M., Williams, C. H. & Allsop, D., 1994, In: Biochemical Society Transactions. 22, 1, p. 16S 1 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  15. Published

    Effects of the mutations Glu22 to Gln and Ala21 to Gly on the aggregation of a synthetic fragment of the Alzheimer's amyloid β/A4 peptide

    Clements, A., Walsh, D. M., Williams, C. H. & Allsop, D., 14/10/1993, In: Neuroscience Letters. 161, 1, p. 17-20 4 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  16. Published

    TDP-43 pathological changes in early onset familial and sporadic Alzheimer's disease, late onset Alzheimer's disease and Down's Syndrome: association with age, hippocampal sclerosis and clinical phenotype

    Davidson, Y. S., Raby, S., Foulds, P., Robinson, A., Thompson, J. C., Sikkink, S., Yusuf, I., Amin, H., Duplessis, D., Troakes, C., Al-Sarraj, S., Sloan, C., Esiri, M. M., Prasher, V. P., Allsop, D., Neary, D., Pickering-Brown, S. M., Snowden, J. S. & Mann, D. M. A., 12/2011, In: Acta Neuropathologica. 122, 6, p. 703-713 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  17. Published

    Alzheimer's disease diagnosis by blood plasma molecular fluorescence spectroscopy (EEM)

    Dos Santos, R. F., Paraskevaidi, M., Mann, D. M. A., Allsop, D., Santos, M. C. D., Morais, C. L. M. & Lima, K. M. G., 28/09/2022, In: Scientific Reports. 12, 1, 13 p., 16199.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  18. Published

    Inflammatory mechanisms in Alzheimer's disease

    Eikelenboom, P., Zhan, S. S., van Gool, W. A. & Allsop, D., 12/1994, In: Trends in Pharmacological Sciences. 15, 12, p. 447-450 4 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  19. Published

    Detection of oligomeric forms of α-synuclein protein in human plasma as a potential biomarker for Parkinson’s disease

    El-Agnaf, O. M. A., Salem, S. A., Paleologou, K. E., Curran, M. D., Gibson, M. J., Court, J. A., Schlossmacher, M. G. & Allsop, D., 2006, In: FASEB Journal. 20, 3, p. 419-425 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  20. Published

    A strategy for designing inhibitors of α-synuclein aggregation and toxicity as a novel treatment for Parkinson's disease and related disorders.

    El-Agnaf, O. M. A., Paleologou, K. E., Greer, B., Abogrein, A. M., King, J., Salem, S. A., Fullwood, N. J., Benson, F. E., Hewitt, R., Ford, K. J., Martin, F., Harriott, P., Cookson, M. R. & Allsop, D., 08/2004, In: FASEB Journal. 18, 11, p. 1315-1317 3 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  21. Published

    α-Synuclein implicated in Parkinson’s disease is present in extracellular biological fluids, including human plasma.

    El-Agnaf, O. M. A., Salem, S. A., Paleologou, K. E., Cooper, L. J., Fullwood, N. J., Gibson, M. J., Curran, M. D., Court, J. A., Mann, D. M. A., Ikeda, S-I., Cookson, M. R., Hardy, J. & Allsop, D., 10/2003, In: FASEB Journal. 17, 13, p. 1945-1947 3 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  22. Published

    Soluble oligomers for the diagnosis of neurodegenerative diseases.

    El-Agnaf, O. M. A., Walsh, D. M. & Allsop, D., 08/2003, In: Lancet Neurology. 2, 8, p. 461-462 2 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  23. Published

    Characterization of an α-secretase candidate from human brain using a new western blot assay

    Evin, G., Reed, G., Tanner, J. E., Li, Q. X., Culvenor, J. G., Fuller, S. J., Wadsworth, H., Allsop, D., Ward, R. V., Karran, E. H., Gray, C. W., Hartmann, T., Lichtenthaler, S. F., Weidemann, A., Beyreuther, K. & Masters, C. L., 1999, Alzheimer's disease and related disorders. Iqbal, K., Swaab, D. F., Winblad, B. & Wisniewski, H. M. (eds.). Wiley, p. 411-418 8 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Conference contribution/Paper › peer-review

  24. Published

    Parkinson disease: progress towards a molecular biomarker for Parkinson disease

    Foulds, P., Mann, D. M. A., Mitchell, J. D. & Allsop, D., 07/2010, In: Nature Reviews Neurology. 6, 7, p. 359-361 3 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  25. Published

    Plasma phosphorylated-TDP-43 protein levels correlate with brain pathology in frontotemporal lobar degeneration

    Foulds, P., Davidson, Y., Mishra, M., Hobson, D. J., Humphreys, K. M., Taylor, M., Johnson, N., Weintraub, S., Akiyama, H., Arai, T., Hasegawa, M., Bigio, E. H., Benson, F. E., Allsop, D. & Mann, D. M. A., 2009, In: Acta Neuropathologica. 118, 5, p. 647-658 12 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

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