Plasma phosphorylated-TDP-43 protein levels correlate with brain pathology in frontotemporal lobar degeneration

Foulds, P., Davidson, Y., Mishra, M., Hobson, D. J., Humphreys, K. M., Taylor, M., Johnson, N., Weintraub, S., Akiyama, H., Arai, T., Hasegawa, M., Bigio, E. H., Benson, F. E., Allsop, D. & Mann, D. M. A., 2009, In: Acta Neuropathologica. 118, 5, p. 647-658 12 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Post mortem cerebrospinal fluid α-synuclein levels are raised in multiple system atrophy and distinguish this from the other α-synucleinopathies, Parkinson's disease and Dementia with Lewy bodies

Foulds, P., Yokota, O., Thurston, A., Davidson, Y., Ahmed, Z., Holton, J., Thompson, J. C., Akiyama, H., Arai, T., Hasegawa, M., Gerhard, A., Allsop, D. & Mann, D. M. A., 01/2012, In: Neurobiology of Disease. 45, 1, p. 188-195 8 p.

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TDP-43 protein in plasma may index TDP-43 brain pathology in Alzheimer's disease and frontotemporal lobar degeneration

Foulds, P., McAuley, E., Gibbons, L., Davidson, Y., Pickering-Brown, S. M., Neary, D., Snowden, J. S., Allsop, D. & Mann, D. M. A., 2008, In: Acta Neuropathologica. 116, 2, p. 141-146 6 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Phosphorylated α-synuclein can be detected in blood plasma and is potentially a useful biomarker for Parkinson's disease

Foulds, P., Mitchell, J. D., Parker, A., Turner, R., Green, G., Diggle, P., Hasegawa, M., Taylor, M., Mann, D. & Allsop, D., 2011, In: The FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 25, 12, p. 4127-4137 11 p.

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Phosphorylated α-synuclein as a potential biomarker for Parkinson's disease (Editorial)

Foulds, P., Mann, D. & Allsop, D., 2012, In: Expert Review of Molecular Diagnostics. 12, 2, p. 115-117 3 p.

Research output: Contribution to Journal/Magazine › Editorial

A longitudinal study on α-synuclein in blood plasma as a biomarker for Parkinson’s disease

Foulds, P., Diggle, P., Mitchell, J. D., Parker, A., Hasegawa, M., Masuda-Suzukake, M., Mann, D. M. A. & Allsop, D., 29/08/2013, In: Scientific Reports. 3, 6 p., 2540.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Detection of oligomeric forms of α-synuclein protein in human plasma as a potential biomarker for Parkinson’s disease

El-Agnaf, O. M. A., Salem, S. A., Paleologou, K. E., Curran, M. D., Gibson, M. J., Court, J. A., Schlossmacher, M. G. & Allsop, D., 2006, In: FASEB Journal. 20, 3, p. 419-425 7 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

A strategy for designing inhibitors of α-synuclein aggregation and toxicity as a novel treatment for Parkinson's disease and related disorders.

El-Agnaf, O. M. A., Paleologou, K. E., Greer, B., Abogrein, A. M., King, J., Salem, S. A., Fullwood, N. J., Benson, F. E., Hewitt, R., Ford, K. J., Martin, F., Harriott, P., Cookson, M. R. & Allsop, D., 08/2004, In: FASEB Journal. 18, 11, p. 1315-1317 3 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

α-Synuclein implicated in Parkinson’s disease is present in extracellular biological fluids, including human plasma.

El-Agnaf, O. M. A., Salem, S. A., Paleologou, K. E., Cooper, L. J., Fullwood, N. J., Gibson, M. J., Curran, M. D., Court, J. A., Mann, D. M. A., Ikeda, S-I., Cookson, M. R., Hardy, J. & Allsop, D., 10/2003, In: FASEB Journal. 17, 13, p. 1945-1947 3 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Soluble oligomers for the diagnosis of neurodegenerative diseases.

El-Agnaf, O. M. A., Walsh, D. M. & Allsop, D., 08/2003, In: Lancet Neurology. 2, 8, p. 461-462 2 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Inflammatory mechanisms in Alzheimer's disease

Eikelenboom, P., Zhan, S. S., van Gool, W. A. & Allsop, D., 12/1994, In: Trends in Pharmacological Sciences. 15, 12, p. 447-450 4 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Alzheimer's disease diagnosis by blood plasma molecular fluorescence spectroscopy (EEM)

Dos Santos, R. F., Paraskevaidi, M., Mann, D. M. A., Allsop, D., Santos, M. C. D., Morais, C. L. M. & Lima, K. M. G., 28/09/2022, In: Scientific Reports. 12, 1, 13 p., 16199.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

TDP-43 pathological changes in early onset familial and sporadic Alzheimer's disease, late onset Alzheimer's disease and Down's Syndrome: association with age, hippocampal sclerosis and clinical phenotype

Davidson, Y. S., Raby, S., Foulds, P., Robinson, A., Thompson, J. C., Sikkink, S., Yusuf, I., Amin, H., Duplessis, D., Troakes, C., Al-Sarraj, S., Sloan, C., Esiri, M. M., Prasher, V. P., Allsop, D., Neary, D., Pickering-Brown, S. M., Snowden, J. S. & Mann, D. M. A., 12/2011, In: Acta Neuropathologica. 122, 6, p. 703-713 11 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Aggregation and metal-binding properties of mutant forms of the amyloid Aβ peptide of Alzheimer's disease

Clements, A., Allsop, D., Walsh, D. M. & Williams, C. H., 02/1996, In: Journal of Neurochemistry. 66, 2, p. 740-747 8 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Aggregation of Alzheimer's peptides

Clements, A., Walsh, D. M., Williams, C. H. & Allsop, D., 1994, In: Biochemical Society Transactions. 22, 1, p. 16S 1 p.

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Effects of the mutations Glu22 to Gln and Ala21 to Gly on the aggregation of a synthetic fragment of the Alzheimer's amyloid β/A4 peptide

Clements, A., Walsh, D. M., Williams, C. H. & Allsop, D., 14/10/1993, In: Neuroscience Letters. 161, 1, p. 17-20 4 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Alzheimer's Disease: correlation of the suppression of β-Amyloid peptide secretion from cultured cells with inhibition of the chymotrypsin-like activity of the proteasome

Christie, G., Markwell, R. E., Gray, C. W., Smith, L., Godfrey, F., Mansfield, F., Wadsworth, H., King, R., McLaughlin, M., Cooper, D. G., Ward, R. V., Howlett, D. R., Hartmann, T., Lichtenthaler, S. F., Beyreuther, K., Underwood, J., Gribble, S. K., Cappai, R., Masters, C. L., Tamaoka, A., & 4 othersGardner, R. L., Rivett, A. J., Karran, E. H. & Allsop, D., 07/1999, In: Journal of Neurochemistry. 73, 1, p. 195-204 10 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Self-Assembly and Anti-Amyloid Cytotoxicity Activity of Amyloid beta Peptide Derivatives

Castelletto, V., Ryumin, P., Cramer, R., Hamley, I., Taylor, M. N., Allsop, D., Reza, M., Ruokolainen, J., Arnold, T., Hermida-Merino, D., Garcia, C. I., Leal, M. C. & Castaño, E., 8/03/2017, In: Scientific Reports. 7, 12 p., 43637.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Designing peptide inhibitors for oligomerization and toxicity of Alzheimer's β-amyloid peptide

Austen, B. M., Paleologou, K. E., Ali, S. A. E., Qureshi, M. M., Allsop, D. & El-Agnaf, O. M. A., 2008, In: Biochemistry. 47, 7, p. 1984-1992 9 p.

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Donepezil for severe Alzheimer's disease.

Allsop, D., Martin, F., Moore, S. & Fullwood, N. J., 29/07/2006, In: Lancet. 368, 9533, p. 361-362 2 p.

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3-p-toluoyl-2-[4′-(3-diethylaminopropoxy)-phenyl]-benzofuran and 2-[4′-(3-diethylaminopropoxy)-phenyl]-benzofuran do not act as surfactants or micelles when inhibiting the aggregation of β-amyloid peptide.

Allsop, D., Gibson, G., Martin, I. K., Moore, S., Turnbull, S. & Twyman, L. J., 01/2001, In: Bioorganic and Medicinal Chemistry Letters. 11, 2, p. 255-257 3 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Fluorescence anisotropy: a method for early detection of Alzheimer β-peptide (Aβ) aggregation.

Allsop, D., Swanson, L., Moore, S., Davies, Y., York, A., El-Agnaf, O. M. A. & Soutar, I., 6/07/2001, In: Biochemical and Biophysical Research Communications. 285, 1, p. 58-63 6 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review