α-synuclein implicated in Parkinson’s disease catalyses the formation of hydrogen peroxide in vitro.

Turnbull, S., Tabner, B. J., Moore, S., Davies, Y., El-Agnaf, O. M. A. & Allsop, D., 15/05/2001, In: Free Radical Biology and Medicine. 30, 10, p. 1163-1170 8 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

3-p-toluoyl-2-[4′-(3-diethylaminopropoxy)-phenyl]-benzofuran and 2-[4′-(3-diethylaminopropoxy)-phenyl]-benzofuran do not act as surfactants or micelles when inhibiting the aggregation of β-amyloid peptide.

Allsop, D., Gibson, G., Martin, I. K., Moore, S., Turnbull, S. & Twyman, L. J., 01/2001, In: Bioorganic and Medicinal Chemistry Letters. 11, 2, p. 255-257 3 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Production of reactive oxygen species from aggregating proteins implicated in Alzheimer's disease, Parkinson's disease and other neurodegenerative diseases.

Tabner, B. J., Turnbull, S., El-Agnaf, O. M. A. & Allsop, D., 2001, In: Current Topics in Medicinal Chemistry. 1, p. 483-493 11 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Pick's disease is associated with mutations in the tau gene.

Pickering-Brown, S., Baker, M., Yen, S.-H., Liu, W.-K., Hasegawa, M., Cairns, N., Lantos, P. L., Rossor, M., Iwatsubo, T., Davies, Y., Allsop, D., Furlong, R., Owen, F., Hardy, J., David Mann, D. & Hutton, M., 12/2000, In: Annals of Neurology. 48, 6, p. 589-867 279 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Characterisation of peptidyl boronic acid inhibitors of mammalian 20S and 26S proteasomes and their inhibition of proteasomes in cultured cells

Gardner, R. C., Assinder, S. J., Christie, G., Mason, G. G. F., Markwell, R., Wadsworth, H., McLaughlin, M., King, R., Chabot-Fletcher, M. C., Breton, J., Allsop, D. & Rivett, A. J., 2000, In: Biochemical Journal. 346, p. 447-454 8 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Modulation of β-amyloid production and fibrillisation

Allsop, D., Twyman, L., Davies, Y., Moore, S., York, A., Swanson, L. & Soutar, I., 2000, In: Biochemical Society Symposia. 67, p. 1-14 14 p.

Research output: Contribution to Journal/Magazine › Literature review › peer-review

A short synthesis of the β-amyloid (Aβ) aggregation inhibitor 3-p-toluoyl-2-[4′-(3-diethylaminopropoxy)-phenyl]-benzofuran.

Twyman, L. J. & Allsop, D., 12/1999, In: Tetrahedron Letters. 40, 52, p. 9383-9384 2 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Alzheimer's Disease: correlation of the suppression of β-Amyloid peptide secretion from cultured cells with inhibition of the chymotrypsin-like activity of the proteasome

Christie, G., Markwell, R. E., Gray, C. W., Smith, L., Godfrey, F., Mansfield, F., Wadsworth, H., King, R., McLaughlin, M., Cooper, D. G., Ward, R. V., Howlett, D. R., Hartmann, T., Lichtenthaler, S. F., Beyreuther, K., Underwood, J., Gribble, S. K., Cappai, R., Masters, C. L. & Tamaoka, A. & 4 others, Gardner, R. L., Rivett, A. J., Karran, E. H. & Allsop, D., 07/1999, In: Journal of Neurochemistry. 73, 1, p. 195-204 10 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review