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Professor David Middleton

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  1. Published

    Solid-state NMR spectroscopy detects interactions between tryptophan residues of the E. coli sugar transporter GalP and the alpha-anomer of the D-glucose substrate

    Patching, S. G., Henderson, P. J. F., Herbert, R. B. & Middleton, D. A., 30/01/2008, In: Journal of the American Chemical Society. 130, 4, p. 1236-44 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  2. Published

    Solid-state NMR studies of adenosine 5'-triphosphate freeze-trapped in the nucleotide site of Na,K-ATPase

    Middleton, D. A., Hughes, E., Fedosova, N. U. & Esmann, M., 20/07/2009, In: June 2002. ISSN 1460-4582. 10, 11, p. 1789-92 4 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  3. Published

    Structural analysis of uniformly (13)C-labelled solids from selective angle measurements at rotational resonance

    Patching, S. G., Edwards, R. & Middleton, D. A., 08/2009, In: June 2002. ISSN 1460-4582. 199, 2, p. 242-6 5 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  4. Published

    Structural insights into the polymorphism of amyloid-like fibrils formed by region 20-29 of amylin revealed by solid-state NMR and X-ray fiber diffraction

    Madine, J., Jack, E., Stockley, P. G., Radford, S. E., Serpell, L. C. & Middleton, D. A., 12/11/2008, In: Journal of the American Chemical Society. 130, 45, p. 14990-5001 12 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  5. Published

    Structures, chemotaxonomic significance, cytotoxic and Na+, K+-ATPase inhibitory activities of new cardenolides from Asclepias curassavica

    Zhang, R-R., Tian, H-Y., Tan, Y-F., Chung, T-Y., Sun, X-H., Xia, X., Ye, W-C., Middleton, D. A., Fedosova, N., Esmann, M., Tzen, J. T. C. & Jiang, R-W., 2014, In: Organic and Biomolecular Chemistry . 12, 44, p. 8919-8929 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  6. Published

    Synthesis of bufalin derivatives with inhibitory activity against prostate cancer cells

    Yuan, X-F., Tian, H-Y., Li, J., Jin, L., Jiang, S-T., Liu, K. W-K., Luo, C., Middleton, D. A., Esmann, M., Ye, W-C. & Jiang, R-W., 3/06/2014, In: Natural Product Research. 28, 11, p. 843-847 5 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  7. Published

    The conformation of ATP within the Na,K-ATPase nucleotide site: a statistically constrained analysis of REDOR solid-state NMR data

    Middleton, D. A., Hughes, E. & Esmann, M., 25/07/2011, In: Angewandte Chemie International Edition. 50, 31, p. 7041-4 4 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  8. Published

    The dynamics and orientation of a lipophilic drug within model membranes determined by 13C solid-state NMR

    Boland, M. P. & Middleton, D. A., 7/01/2008, In: Physical Chemistry Chemical Physics. 10, 1, p. 178-85 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  9. Published

    The effects of alpha-synuclein on phospholipid vesicle integrity: a study using 31P NMR and electron microscopy

    Madine, J., Hughes, E., Doig, A. J. & Middleton, D. A., 09/2008, In: Molecular Membrane Biology. 25, 6-7, p. 518-27 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  10. Published

    Vascular smooth muscle cell senescence accelerates medin aggregation via small extracellular vesicle secretion and extracellular matrix reorganization

    Whitehead, M., Yusoff, S., Ahmad, S., Schmidt, L., Mayr, M., Madine, J., Middleton, D. & Shanahan, C., 28/02/2023, In: Aging Cell. 22, 2, 19 p., e13746.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

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