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Research

Dr Edward Parkin

Senior Lecturer in Biomedicine

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  1. 2024
  2. Published

    Progress towards understanding risk factor mechanisms in the development of autism spectrum disorders

    Bryers, A., Hawkes, C. A., Parkin, E. & Dawson, N., 30/10/2024, In: Biochemical Society Transactions. 52, 5, p. 2047-2058 12 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  3. Published

    Protective effect of PDE4B subtype-specific inhibition in an App knock-in mouse model for Alzheimer's disease

    Armstrong, P., Güngör, H., Anongjanya, P., Tweedy, C., Parkin, E., Johnston, J., Carr, I. M., Dawson, N. & Clapcote, S. J., 09/2024, In: Neuropsychopharmacology. 49, 10, p. 1559-1568 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  4. Published

    Liposome nanoparticle conjugation and cell penetrating peptide sequences ( CPPs ) enhance the cellular delivery of the tau aggregation inhibitor RI ‐ AG03

    Reich, N., Parkin, E. & Dawson, N., 1/06/2024, In: Journal of Cellular and Molecular Medicine. 28, 11, e18477.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  5. 2022
  6. Published

    BACE1 Overexpression Reduces SH-SY5Y Cell Viability Through a Mechanism Distinct from Amyloid-β Peptide Accumulation: Beta Prime-Mediated Competitive Depletion of sAβPPα

    Owens, L., Bracewell, J., Benedetto, A., Dawson, N., Gaffney, C. & Parkin, E., 5/04/2022, In: Journal of Alzheimer's Disease. 86, 3, p. 1201-1220 20 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  7. Published

    The Amyloid Precursor Protein Plays Differential Roles in the UVA Resistance and Proliferation of Human Retinal Pigment Epithelial Cells

    Sultan, F. & Parkin, E., 30/03/2022, In: Protein and Peptide Letters. 29, 4, p. 313-327 15 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  8. Published

    The orphan drug dichloroacetate reduces amyloid beta-peptide production whilst promoting non-amyloidogenic proteolysis of the amyloid precursor protein

    Parkin, E. T., Hammond, J. E., Owens, L. & Hodges, M. D., 13/01/2022, In: PLoS ONE. 17, 1, 21 p., e0255715.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  9. 2021
  10. Published

    Gene therapy-mediated enhancement of protective protein expression for the treatment of Alzheimer's disease

    Owens, L., Benedetto, A., Dawson, N., Gaffney, C. & Parkin, E., 15/02/2021, In: Brain Research. 1753, 12 p., 147264.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  11. 2018
  12. Published

    Osteonectin as a screening marker for pancreatic cancer: A prospective study

    Papapanagiotou, A., Sgourakis, G., Karkoulias, K., Raptis, D., Parkin, E. T., Brotzakis, P., Panchal, S. & Papavassiliou, A., 1/07/2018, In: Journal of International Medical Research. 46, 7, p. 2769-2779 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  13. 2016
  14. Published

    Notch Signalling as a Therapeutic Target in Cancer

    Martinas, I. & Parkin, E. T., 10/2016, In: International Journal of Cancer Therapy and Oncology. 4, 4

    Research output: Contribution to Journal/Magazine › Literature review › peer-review

  15. Published

    Pyruvate dehydrogenase kinase inhibition: reversing the Warburg effect in cancer therapy

    Bell, H. & Parkin, E. T., 23/06/2016, In: International Journal of Cancer Therapy and Oncology. 4, 2, p. 4215-4227 12 p.

    Research output: Contribution to Journal/Magazine › Literature review › peer-review

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