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Dr Edward Parkin

Senior Lecturer in Biomedicine

  1. Published

    Differential effects of glycosphingolipids on the detergent-insolubility of the glycosylphosphatidylinositol-anchored membrane dipeptidase.

    Parkin, E. T., Turner, A. J. & Hooper, N. M., 15/08/2001, In: Biochemical Journal. 358, 1, p. 209-216 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  2. Published

    Amyloid precursor protein, although partially detergent-insoluble in mouse cerebral cortex, behaves as an atypical lipid raft protein.

    Parkin, E. T., Turner, A. J. & Hooper, N. M., 15/11/1999, In: Biochemical Journal. 344, 1, p. 23-30 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  3. Published

    Characterization of Detergent-Insoluble Complexes Containing the Familial Alzheimer's Disease-Associated Presenilins.

    Parkin, E. T., Hussain, I., Karran, E. H., Turner, A. J. & Hooper, N. M., 04/1999, In: Journal of Neurochemistry. 72, 4, p. 1534-1543 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  4. Published

    Modulation of phosphatidylcholine biosynthesis in celery by exogenous fatty acids.

    Parkin, E. T. & Rolphe, C. E., 15/01/1999, In: Phytochemistry. 50, 1, p. 47-51 5 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  5. Published

    Secretase-mediated cell surface shedding of the angiotensin-converting enzyme.

    Parkin, E. T., Turner, A. J. & Hooper, N. M., 2004, In: Protein and Peptide Letters. 11, p. 423-432 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  6. Published

    Distribution of presenilins and amyloid precursor protein in detergent-insoluble membrane domains.

    Parkin, E. T., Turner, A. J. & Hooper, N. M., 1999, Alzheimer's disease : methods and protocols. Walker, J. M. (ed.). Humana Press, p. 345-360 16 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNChapter

  7. Published

    The Alzheimer's amyloid precursor protein a-secretase and the angiotensin converting enzyme secretase exhibit closely related enzyme activities.

    Parkin, E. T., Turner, A. J. & Hooper, N. M., 2000.

    Research output: Contribution to conference - Without ISBN/ISSN Other

  8. Published

    Caveolae-like membranes and the amyloid precursor protein : a critical reassessment.

    Parkin, E. T., Turner, A. J. & Hooper, N. M., 1999, In: British Neuroscience Association Abstracts. 15, p. 59

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  9. Published

    Caveolae-like membranes and the amyloid precursor protein : a critical reassessment.

    Parkin, E. T., Turner, A. J. & Hooper, N. M., 06/1999, In: Journal of Neurochemistry. 72, Supple, p. S71

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  10. Published

    A disintegrin and metalloproteinase (ADAM)-mediated ectodomain shedding of ADAM10

    Parkin, E. & Harris, B., 03/2009, In: Journal of Neurochemistry. 108, 6, p. 1464-1479 16 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  11. Published

    Phoshatidylcholine biosynthesis and cell growth in Apium graveolens

    Parkin, E. & Rolph, C., 08/1995, In: Physiologia Plantarum. 94, 4, p. 643-650 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  12. Published

    Isolation and characterization of two distinct low-density, Triton-insoluble, complexes from porcine lung membranes

    Parkin, E., Turner, A. J. & Hooper, N. M., 1996, In: Biochemical Journal. 319 , 3, p. 887-896 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  13. Published

    The amyloid precursor protein is not enriched in caveolae-like, detergent-insoluble membrane microdomains

    Parkin, E., Hussain, I., Turner, A. J. & Hooper, N. M., 11/1997, In: Journal of Neurochemistry. 69, 5, p. 2179-2188 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  14. Published

    A role for calcium and annexins in the formation of caveolae

    Parkin, E., Turner, A. J. & Hooper, N. M., 08/1996, In: Biochemical Society Transactions. 24, 3, p. 444S 1 p.

    Research output: Contribution to Journal/MagazineJournal article

  15. Published

    Distribution of presenilins and amyloid precursor protein in detergent-insoluble membrane microdomains

    Parkin, E., Turner, A. & Hooper, N., 1999, Alzheimer's disease: methods and protocols. Hooper, N. M. (ed.). Humana Press, p. 345-360 16 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNChapter

  16. Published

    Alpha-Secretase and Alzheimer's disease

    Parkin, E., 2008, Recent advances in the biology of secretases, key proteases in Alzheimer's disease. Araki, W. (ed.). Research Signpost, p. 183-211 29 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNChapter

  17. Published

    Cell proliferation and CTP: cholinephosphate cytidyhltraitsferase activity in higher plahts

    Parkin, E. T. & Rolph, C. E., 1/08/1998, In: Biochemical Society Transactions. 26, 3, p. S219

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  18. Published

    Detergent solubility and processing of the familial Alzheimer's disease-related presenilin proteins

    Parkin, E. T., Turner, A. J. & Hooper, N. M., 1/08/1998, In: Biochemical Society Transactions. 26, 3, p. S241

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  19. Published

    Effects of sterol biosynthesis inhibitors on phosphatidylcholine biosynthesis in Apium graveolens

    Parkin, E. T., Goad, L. J. & Rolph, C. E., 1/11/1994, In: Biochemical Society Transactions. 22, 4, p. 432S

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  20. Published

    Studies on CTP: Cholinephosphate cytidylyltransferase in Apium graveolens

    Parkin, E. T., Goad, J. L. & Rolph, C. E., 1/05/1993, In: Biochemical Society Transactions. 21, 2, p. 77S

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  21. Published

    The orphan drug dichloroacetate reduces amyloid beta-peptide production whilst promoting non-amyloidogenic proteolysis of the amyloid precursor protein

    Parkin, E. T., Hammond, J. E., Owens, L. & Hodges, M. D., 13/01/2022, In: PLoS ONE. 17, 1, 21 p., e0255715.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  22. Published

    Ectodomain shedding of the Notch ligand Jagged1 is mediated by ADAM17, but is not a lipid-raft-associated event

    Parr-Sturgess, C. A., Rushton, D. J. & Parkin, E. T., 2010, In: Biochemical Journal. 432, 2, p. 283-294 12 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  23. Published

    Copper modulates zinc metalloproteinase-dependent ectodomain shedding of key signalling and adhesion proteins and promotes the invasion of prostate cancer epithelial cells

    Parr-Sturgess, C. A., Tinker, C. L., Hart, C. A., Brown, M. D., Clarke, N. W. & Parkin, E. T., 10/2012, In: Molecular Cancer Research. 10, 10, p. 1282-1293 12 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  24. Published

    Herpes simplex virus interferes with amyloid precursor protein processing.

    Shipley, S. J., Parkin, E. T., Itzhaki, R. F. & Dobson, C. B., 18/08/2005, In: BMC Microbiology. 5, p. 48

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  25. Published

    The Amyloid Precursor Protein Plays Differential Roles in the UVA Resistance and Proliferation of Human Retinal Pigment Epithelial Cells

    Sultan, F. & Parkin, E., 30/03/2022, In: Protein and Peptide Letters. 29, 4, p. 313-327 15 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

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