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Dr Edward Parkin

Senior Lecturer in Biomedicine

  1. Journal article
  2. Published

    Membrane raft actin deficiency and altered Ca2+-induced vesiculation in stomatin-deficient overhydrated hereditary stomatocytosis

    Wilkinson, D. K., Turner, E. J., Parkin, E. T., Garner, A. E., Harrison, P. J., Crawford, M., Stewart, G. W. & Hooper, N. M., 01/2008, In: Biochimica et Biophysica Acta (BBA) - Biomembranes. 1778, 1, p. 125-132 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  3. Published

    Cellular pion protein regulates beta-secretase cleavage of the Alzheimers amyloid precurs protein.

    Parkin, E., Watt, N. T., Hussain, I., Eckman, E. A., Eckman, C. B., Manson, J. C., Baybutt, H. N., Turner, A. J. & Hooper, N. M., 26/06/2007, In: Proceedings of the National Academy of Sciences of the United States of America. 104, 26, p. 11062-11067 6 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  4. Published

    Angiotensin-converting enzyme as a GPlase : a critical reevaluation.

    Leisle, L., Parkin, E. T., Turner, A. J. & Hooper, N. M., 11/2005, In: Nature Medicine. 11, 11, p. 1139-1140 2 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  5. Published

    Tumor Necrosis Factor- Convertase (ADAM17) Mediates Regulated Ectodomain Shedding of the Severe-acute Respiratory Syndrome-Coronavirus (SARS-CoV) Receptor, Angiotensin-converting Enzyme-2 (ACE2).

    Lambert, D. W., Yarski, M., Warner, F. J., Thornhill, P., Parkin, E. T., Smith, A. I., Hooper, N. M. & Turner, A. J., 26/08/2005, In: Journal of Biological Chemistry. 280, 34, p. 30113-30119 7 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  6. Published

    Herpes simplex virus interferes with amyloid precursor protein processing.

    Shipley, S. J., Parkin, E. T., Itzhaki, R. F. & Dobson, C. B., 18/08/2005, In: BMC Microbiology. 5, p. 48

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  7. Published

    The role of ADAM10 and ADAM17 in the ectodomain shedding of angiotensin converting enzyme and the amyloid precursor protein.

    Allinson, T. M. J., Parkin, E. T., Condon, T. P., Schwager, S. L. U., Sturrock, E. D., Turner, A. J. & Hooper, N. M., 06/2004, In: European Journal of Biochemistry. 271, 12, p. 2539-2547 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  8. Published

    Dual Mechanisms for Shedding of the Cellular Prion Protein.

    Parkin, E. T., Watt, N. T., Turner, A. J. & Hooper, N. M., 19/03/2004, In: Journal of Biological Chemistry. 279, 12, p. 11170-11178 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  9. Published

    Secretase-mediated cell surface shedding of the angiotensin-converting enzyme.

    Parkin, E. T., Turner, A. J. & Hooper, N. M., 2004, In: Protein and Peptide Letters. 11, p. 423-432 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  10. Published

    ADAMs family members as amyloid precursor protein -secretases.

    Allinson, T. M. J., Parkin, E. T., Turner, A. J. & Hooper, N. M., 1/11/2003, In: Journal of Neuroscience Research. 74, 3, p. 342-352 11 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  11. Published

    The ectodomain shedding of angiotensin-converting enzyme is independent of its localisation in lipid rafts.

    Parkin, E. T., Tan, F., Skidgel, R. A., Turner, A. J. & Hooper, N. M., 1/08/2003, In: Journal of Cell Science. 116, 15, p. 3079-3087 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  12. Published

    Structure-Activity Relationship of Hydroxamate-Based Inhibitors on the Secretases that Cleave the Amyloid Precursor Protein, Angiotensin Converting Enzyme, CD23, and Pro-Tumor Necrosis Factor.

    Parkin, E. T., Trew, A., Christie, G., Faller, A., Mayer, R., Turner, A. J. & Hooper, N. M., 16/04/2002, In: Biochemistry. 41, 15, p. 4972-4981 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  13. Published

    Inactivation of a tachykinin-related peptide: identification of four neuropeptide-degrading enzymes in neuronal membranes of insects from four different orders.

    Isaac, R. E., Parkin, E. T., Keen, J. N., Nässel, D. R., Siviter, R. J. & Shirras, A. D., 04/2002, In: Peptides. 23, 4, p. 725-733 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  14. Published

    Differential effects of glycosphingolipids on the detergent-insolubility of the glycosylphosphatidylinositol-anchored membrane dipeptidase.

    Parkin, E. T., Turner, A. J. & Hooper, N. M., 15/08/2001, In: Biochemical Journal. 358, 1, p. 209-216 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  15. Published

    A Point Mutation in the Juxtamembrane Stalk of Human Angiotensin I-converting Enzyme Invokes the Action of a Distinct Secretase.

    Alfalah, M., Parkin, E. T., Jacob, R., Sturrock, E. D., Mentele, R., Turner, A. J., Hooper, N. M. & Naim, H. Y., 15/06/2001, In: Journal of Biological Chemistry. 276, 24, p. 21105-21109 5 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  16. Published

    Amyloid precursor protein, although partially detergent-insoluble in mouse cerebral cortex, behaves as an atypical lipid raft protein.

    Parkin, E. T., Turner, A. J. & Hooper, N. M., 15/11/1999, In: Biochemical Journal. 344, 1, p. 23-30 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  17. Published

    Caveolae-like membranes and the amyloid precursor protein : a critical reassessment.

    Parkin, E. T., Turner, A. J. & Hooper, N. M., 06/1999, In: Journal of Neurochemistry. 72, Supple, p. S71

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  18. Published

    Characterization of Detergent-Insoluble Complexes Containing the Familial Alzheimer's Disease-Associated Presenilins.

    Parkin, E. T., Hussain, I., Karran, E. H., Turner, A. J. & Hooper, N. M., 04/1999, In: Journal of Neurochemistry. 72, 4, p. 1534-1543 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  19. Published

    Modulation of phosphatidylcholine biosynthesis in celery by exogenous fatty acids.

    Parkin, E. T. & Rolphe, C. E., 15/01/1999, In: Phytochemistry. 50, 1, p. 47-51 5 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  20. Published

    Caveolae-like membranes and the amyloid precursor protein : a critical reassessment.

    Parkin, E. T., Turner, A. J. & Hooper, N. M., 1999, In: British Neuroscience Association Abstracts. 15, p. 59

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  21. Published

    Cell proliferation and CTP: cholinephosphate cytidyhltraitsferase activity in higher plahts

    Parkin, E. T. & Rolph, C. E., 1/08/1998, In: Biochemical Society Transactions. 26, 3, p. S219

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  22. Published

    Detergent solubility and processing of the familial Alzheimer's disease-related presenilin proteins

    Parkin, E. T., Turner, A. J. & Hooper, N. M., 1/08/1998, In: Biochemical Society Transactions. 26, 3, p. S241

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  23. Published

    The amyloid precursor protein is not enriched in caveolae-like, detergent-insoluble membrane microdomains

    Parkin, E., Hussain, I., Turner, A. J. & Hooper, N. M., 11/1997, In: Journal of Neurochemistry. 69, 5, p. 2179-2188 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  24. Published

    A role for calcium and annexins in the formation of caveolae

    Parkin, E., Turner, A. J. & Hooper, N. M., 08/1996, In: Biochemical Society Transactions. 24, 3, p. 444S 1 p.

    Research output: Contribution to Journal/MagazineJournal article

  25. Published

    Isolation and characterization of two distinct low-density, Triton-insoluble, complexes from porcine lung membranes

    Parkin, E., Turner, A. J. & Hooper, N. M., 1996, In: Biochemical Journal. 319 , 3, p. 887-896 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  26. Published

    Phoshatidylcholine biosynthesis and cell growth in Apium graveolens

    Parkin, E. & Rolph, C., 08/1995, In: Physiologia Plantarum. 94, 4, p. 643-650 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

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