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Research

Dr Geoffrey Akien

Experimental Officer (NMR)

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  1. Published

    An amide hydrogen bond templated [1]rotaxane displaying a peptide motif - demonstrating an expedient route to synthetic mimics of lasso peptides

    Young, M. J., Akien, G. R. & Evans, N. H., 21/07/2020, In: Organic and Biomolecular Chemistry . 18, 27, p. 5203-5209 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  2. Published

    Continuous hydroformylation with phosphine-functionalized polydimethylsiloxane rhodium complexes as nanofilterable homogeneous catalysts

    Xie, Z., Akien, G. R., Sarkar, B. R., Subramaniam, B. & Chaudhari, R. V., 14/10/2015, In: Industrial and Engineering Chemistry Research. 54, 43, p. 10656-10660 5 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  3. Published

    Epigallocatechin-3-gallate remodels apolipoprotein A-I amyloid fibrils into soluble oligomers in the presence of heparin

    Townsend, D., Hughes, E., Akien, G., Stewart, K. L., Radford, S. E., Rochester, D. & Middleton, D. A., 17/08/2018, In: Journal of Biological Chemistry. 293, 33, p. 12877-12893 17 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  4. Published

    [N,N-Bis(2-hy­droxy­eth­yl)di­thio­carbamato-[kappa]2S,S']bis­(tri­phenyl­phosphane-[kappa]P)copper(I) chloro­form monosolvate: crystal structure, Hirshfeld surface analysis and solution NMR measurements

    Tan, S. L., Yeo, C. I., Heard, P. J., Akien, G. R., Halcovitch, N. R. & Tiekink, E. R. T., 12/2016, In: Acta Crystallographica Section E: Crystallographic Communications. 72, 12, p. 1799-1805 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  5. Published

    Supercritical fluids and gas-expanded liquids as tunable media for multiphase catalytic reactions

    Subramaniam, B., Chaudhari, R. V., Chaudhari, A. S., Akien, G. R. & Xie, Z., 1/08/2014, In: Chemical Engineering Science. 115, p. 3-18 16 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  6. Published

    Sustainable catalytic reaction engineering with gas-expanded liquids

    Subramaniam, B. & Akien, G. R., 1/08/2012, In: Current Opinion in Chemical Engineering. 1, 3, p. 336-341 6 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  7. Published

    Atomic details of the interactions of Glycosaminoglycans with amyloid-β fibrils

    Stewart, K., Hughes, E., Yates, E., Akien, G. R., Huang, T-Y., Lima, M., Rudd, T., Guerrini, M., Hung, S-C., Radford, S. & Middleton, D. A., 13/07/2016, In: Journal of the American Chemical Society. 138, 27, p. 8328-8331 4 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  8. Published

    Accelerated acquisition in pure-shift spectra based on prior knowledge from 1H NMR

    Shchukina, A., Kaźmierczak, M., Kasprzak, P., Davy, M., Akien, G., Butts, C. & Kazimierczuk, K., 18/07/2019, In: Chemical Communications. 55, 64, p. 9563-9566 4 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  9. Published

    Dinucleating Schiff base ligand in Zn/4f coordination chemistry: synthetic challenges and catalytic activity evaluation

    Sampani, S. I., Aubert, S., Cattoen, M., Griffiths, K., Abdul-Sada, A., Akien, G. R., Tizzard, G. J., Coles, S. J., Arseniyadis, S. & Kostakis, G. E., 7/04/2018, In: Dalton Transactions. 47, 13, p. 44786-4493 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  10. Published

    Catalytic conversion of fructose, glucose, and sucrose to 5-(hydroxymethyl)furfural and levulinic and formic acids in gamma-valerolactone as a green solvent

    Qi, L., Mui, Y. F., Lo, S. W., Lui, M. Y., Akien, G. R. & Horvath, I. T., 05/2014, In: ACS Catalysis. 4, 5, p. 1470-1477 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  11. Published

    Self-optimizing continuous reactions in supercritical carbon dioxide

    Parrott, A. J., Bourne, R. A., Akien, G. R., Irvine, D. J. & Poliakoff, M., 11/04/2011, In: Angewandte Chemie International Edition. 50, 16, p. 3788-3792 5 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  12. Published

    Synthesis in Green Solvents

    Orha, L., Akien, G. & Horvath, I. T., 15/04/2012, Handbook of Green Chemistry: Online. Wiley-VCH, Vol. 7.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Chapter (peer-reviewed) › peer-review

  13. Published

    Electroactive Silk Fibroin Films for Electrochemically Enhanced Delivery of Drugs

    Mousavi, S., Harper, G., Municoy, S., Ashton, M., Townsend, D., Alsharif, G., Oikonomou, V., Au-Yong, S., Murdock, B., Akien, G., Halcovitch, N., Baldock, S., Fazilati, M., Kolosov, O., Robinson, B., Desimone, M. & Hardy, J., 1/06/2020, In: Macromolecular Materials and Engineering. 305, 6, 7 p., 2000130.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  14. Published

    Photochemical Oxidation of Pt(IV)Me3(1,2-diimine) Thiolates to Luminescent Pt(IV) Sulfinates

    Mala, B., Murtagh, L., Farrow, C., Akien, G., Halcovitch, N., Allinson, S., Platts, J. A. & Coogan, M., 17/05/2021, In: Inorganic Chemistry. 60, 10, p. 7031-7043 13 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  15. Published

    Intensified and safe ozonolysis of fatty acid methyl esters in liquid CO2 in a continuous reactor

    Lundin, M. D., Danby, A. M., Akien, G. R., Venkitasubramanian, P., Martin, K. J., Busch, D. H. & Subramaniam, B., 07/2017, In: AIChE Journal. 63, 7, p. 2819-2826 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  16. Published

    Dinuclear Lanthanide (III) Coordination Polymers in a Domino Reaction

    Loukopoulos, E., Griffiths, K., Akien, G., Kourkomelis, N., Abdul-Sada, A. & Kostakis, G. E., 6/11/2015, In: Inorganics. 3, 4, p. 448-466 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  17. Published

    Synthesis of Diverse Allylsilanes Employing Brønsted Acid Catalyzed Reductive Functionalization

    Leonard, E., Akien, G., Britten, T., Kazi, N., Roberts, D. & McLaughlin, M., 21/11/2023, In: Advanced Synthesis & Catalysis. 365, 22, p. 3872-3875 5 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  18. Published

    Detecting phase transitions in supercritical mixtures: an enabling tool for greener chemical reactions

    Ke, J., Sanchez-Vicente, Y., Akien, G. R., Novitskiy, A. A., Comak, G., Bagratashvili, V. N., George, M. W. & Poliakoff, M., 8/10/2010, In: Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences. 466, 2122, p. 2799-2818 20 p.

    Research output: Contribution to Journal/Magazine › Literature review › peer-review

  19. Published

    Enhanced process development using automated continuous reactors by self-optimisation algorithms and statistical empirical modelling

    Jeraal, M. I., Holmes, N., Akien, G. R. & Bourne, R. A., 21/06/2018, In: Tetrahedron. 74, 25, p. 3158-3164 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  20. Published

    Sustainable synthesis of gamma-valerolactone

    Horvath, I. T., Qi, L. & Akien, G. R., 27/03/2011, In: Abstracts of Papers of the American Chemical Society. 241, 1 p.

    Research output: Contribution to Journal/Magazine › Meeting abstract › peer-review

  21. Published

    Rapid multistep kinetic model generation from transient flow data

    Hone, C. A., Holmes, N., Akien, G. R., Bourne, R. A. & Muller, F. L., 1/04/2017, In: Reaction Chemistry and Engineering. 2, 2, p. 103-108 6 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  22. Published

    Online quantitative mass spectrometry for the rapid adaptive optimisation of automated flow reactors

    Holmes, N., Akien, G. R., Savage, R. J. D., Stanetty, C., Baxendale, I. R., Blacker, A. J., Taylor, B. A., Woodward, R. L., Meadows, R. E. & Bourne, R. A., 2016, In: Reaction Chemistry and Engineering. 2016, 1, p. 96-100 5 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  23. Published

    Self-optimisation of the final stage in the synthesis of EGFR kinase inhibitor AZD9291 using an automated flow reactor

    Holmes, N., Akien, G. R., Blacker, A. J., Woodward, R. L., Meadows, R. E. & Bourne, R. A., 1/08/2016, In: Reaction Chemistry and Engineering. 1, 4, p. 366-371 6 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  24. Published

    Tetranuclear Zn/4f coordination clusters as highly efficient catalysts for Friedel–Crafts alkylation

    Griffiths, K., Kumar, P., Akien, G. R., Chilton, N. F., Abdul-Sada, A., Tizzard, G. J., Coles, S. J. & Kostakis, G. E., 25/06/2016, In: Chemical Communications. 52, 50, p. 7866-7869 4 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  25. Published

    3d/4f Coordination Clusters as Cooperative Catalysts for Highly Diastereoselective Michael Addition Reactions

    Griffiths, K., Tsipis, A. C., Kumar, P., Townrow, O. P. E., Abdul-Sada, A., Akien, G. R., Baldansuren, A., Spivey, A. C. & Kostakis, G. E., 21/08/2017, In: Inorganic Chemistry. 56, 16, p. 9563-9573 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

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