Genome-wide association studies suggest limited immune gene enrichment in schizophrenia compared to 5 autoimmune diseases

Pouget, J. G., Gonçalves, V. F., Spain, S. L., Finucane, H. K., Raychaudhuri, S., Kennedy, J. L., Knight, J. & Schizophrenia Working Group of the Psychiatric Genomics Consortium, 09/2016, In: Schizophrenia Bulletin. 42, 5, p. 1176-1184 9 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Genetic Markers of Human Evolution Are Enriched in Schizophrenia

Schizophrenia Working Group of the Psychiatric Genomics Consortium, The International Headache Genetics Consortium, 15/08/2016, In: Biological Psychiatry. 80, 4, p. 284-92 9 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

CEREBRAL PERFUSION AS AN IMAGING BIOMARKER OF PRESYMPTOMATIC GENETIC FRONTOTEMPORAL DEMENTIA: PRELIMINARY RESULTS FROM THE GENETIC FRONTOTEMPORAL DEMENTIA INITIATIVE (GENFI)

Mutsaerts, H. J. M. M. & Knight, J., 07/2016, In: Alzheimer's and Dementia. 12, 7 Suppl., p. P409-P411 3 p.

Research output: Contribution to Journal/Magazine › Meeting abstract

Dopamine D2 receptor gene variants and response to rasagiline in early Parkinson's disease: a pharmacogenetic study

Masellis, M., Collinson, S., Freeman, N., Tampakeras, M., Levy, J., Tchelet, A., Eyal, E., Berkovich, E., Eliaz, R. E., Abler, V., Grossman, I., Fitzer-Attas, C., Tiwari, A., Hayden, M. R., Kennedy, J. L., Lang, A. E., Knight, J. & ADAGIO investigators, 07/2016, In: Brain. 139, 7, p. 2050-2062 13 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Identification of Gene Loci That Overlap Between Schizophrenia and Educational Attainment

Schizophrenia Working Group of the Psychiatric Genomics Consortium, 26/06/2016, In: Schizophrenia Bulletin. 43, 3, p. 654-664 11 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Investigating the causal relationship of C-reactive protein with 32 complex somatic and psychiatric outcomes: a large-scale cross-consortium Mendelian randomization study

Prins, B. P., Abbasi, A., Wong, A., Vaez, A., Nolte, I., Franceschini, N., Stuart, P. E., Guterriez Achury, J., Mistry, V., Bradfield, J. P., Valdes, A. M., Bras, J., Shatunov, A., Lu, C., Han, B., Raychaudhuri, S., Bevan, S., Mayes, M. D., Tsoi, L. C. & Evangelou, E. & 28 others, Nair, R. P., Grant, S. F. A., Polychronakos, C., Radstake, T. R. D., van Heel, D. A., Dunstan, M. L., Wood, N. W., Al-Chalabi, A., Dehghan, A., Hakonarson, H., Markus, H. S., Elder, J. T., Knight, J., Arking, D. E., Spector, T. D., Koeleman, B. P. C., van Duijn, C. M., Martin, J., Morris, A. P., Weersma, R. K., Wijmenga, C., Munroe, P. B., Perry, J. R. B., Pouget, J. G., Jamshidi, Y., Snieder, H., Alizadeh, B. Z. & PAGE Consortium, 21/06/2016, In: PLoS Medicine. 13, 6, 29 p., e1001976.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Allele-skewed DNA modification in the brain: relevance to a schizophrenia GWAS

Gagliano, S. A., Ptak, C., Mak, D. Y. F., Shamsi, M., Oh, G., Knight, J., Boutros, P. C. & Petronis, A., 5/05/2016, In: American Journal of Human Genetics. 98, 5, p. 956-962 7 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Gene prioritization for imaging genetics studies using gene ontology and a stratified false discovery rate approach

Patel, S., Park, M. T. M., Chakravarty, M. M., Knight, J. & Alzheimer's Disease Neuroimaging Initiative, 7/04/2016, In: Frontiers in Neuroinformatics. 10, 13 p., 14.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Analyzing the Role of MicroRNAs in Schizophrenia in the Context of Common Genetic Risk Variants

Schizophrenia Working Group of the Psychiatric Genomics Consortium, 04/2016, In: JAMA Psychiatry. 73, 4, p. 369-377 9 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Genetic association analysis of N-methyl-d-aspartate receptor subunit gene GRIN2B and clinical response to clozapine

Taylor, D. L., Tiwari, A. K., Lieberman, J. A., Potkin, S. G., Meltzer, H. Y., Knight, J., Remington, G., Müller, D. J. & Kennedy, J. L., 03/2016, In: Human Psychopharmacology: Clinical and Experimental. 31, 2, p. 121-134 14 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept

Schizophrenia Working Group of the Psychiatric Genomics Consortium, 03/2016, In: Nature Reviews Neuroscience. 19, 3, p. 420-431 12 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Genome-wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness

Schizophrenia Working Group of the Psychiatric Genomics Consortium, 03/2016, In: American Journal of Medical Genetics Part B: Neuropsychiatric Genetics . 171B, 2, p. 276-89 14 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Estimating Effect Sizes and Expected Replication Probabilities from GWAS Summary Statistics

Schizophrenia Working Group of the Psychiatric Genomics Consortium, 16/02/2016, In: Frontiers in Genetics. 7, 13 p., 15.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Schizophrenia risk from complex variation of complement component 4

Schizophrenia Working Group of the Psychiatric Genomics Consortium, 11/02/2016, In: Nature. 530, 7589, p. 177-183 7 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

IBD genetic risk profile in healthy first-degree relatives of Crohn's disease patients

Kevans, D., Silverberg, M. S., Borowski, K., Griffiths, A., Xu, W., Onay, V., Paterson, A. D., Knight, J., Croitoru, K. & GEM Project, 02/2016, In: Journal of Crohn's and Colitis. 10, 2, p. 209-215 7 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Leveraging Genomic Annotations and Pleiotropic Enrichment for Improved Replication Rates in Schizophrenia GWAS

Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium, 01/2016, In: PLoS Genetics. 12, 1, 22 p., e1005803.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis

Schizophrenia Working Group of Psychiatric Genomics Consortium, 12/2015, In: Nature Genetics. 47, 12, p. 1385-1392 8 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Modeling linkage disequilibrium increases accuracy of polygenic risk scores

Schizophrenia Working Group of the Psychiatric Genomics Consortium, Discovery, Biology, and Risk of Inherited Variants in Breast Cancer (DRIVE) study, 1/10/2015, In: American Journal of Human Genetics. 97, 4, p. 576-592 17 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Predictors of outcome in ulcerative colitis

Waterman, M., Knight, J., Dinani, A., Xu, W., Stempak, J. M., Croitoru, K., Nguyen, G. C., Cohen, Z., McLeod, R. S., Greenberg, G. R., Steinhart, A. H. & Silverberg, M. S., 09/2015, In: Inflammatory Bowel Diseases. 21, 9, p. 2097-2105 9 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Smoking gun or circumstantial evidence? comparison of statistical learning methods using functional annotations for prioritizing risk variants

Gagliano, S. A., Ravji, R., Barnes, M. R., Weale, M. E. & Knight, J., 24/08/2015, In: Scientific Reports. 5, 11 p., 13373.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Addiction-related genes in gambling disorders: new insights from parallel human and pre-clinical models

Lobo, D. S. S., Aleksandrova, L., Knight, J., Casey, D. M., el-Guebaly, N., Nobrega, J. N. & Kennedy, J. L., 08/2015, In: Molecular Psychiatry. 20, 8, p. 1002-1010 9 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

A genome-wide association study of suicide severity scores in bipolar disorder

Zai, C. C., Gonçalves, V. F., Tiwari, A. K., Gagliano, S. A., Hosang, G., de Luca, V., Shaikh, S. A., King, N., Chen, Q., Xu, W., Strauss, J., Breen, G., Lewis, C. M., Farmer, A. E., McGuffin, P., Knight, J., Vincent, J. B. & Kennedy, J. L., 06/2015, In: Journal of Psychiatric Research. 65, p. 23-29 7 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Assessing models for genetic prediction of complex traits: a comparison of visualization and quantitative methods

Gagliano, S. A., Paterson, A. D., Weale, M. E. & Knight, J., 22/05/2015, In: BMC Genomics. 16, 11 p., 405.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Enhanced meta-analysis and replication studies identify five new psoriasis susceptibility loci

Tsoi, L. C., Spain, S. L., Ellinghaus, E., Stuart, P. E., Capon, F., Knight, J., Tejasvi, T., Kang, H. M., Allen, M. H., Lambert, S., Stoll, S. W., Weidinger, S., Gudjonsson, J. E., Koks, S., Kingo, K., Esko, T., Das, S., Metspalu, A., Weichenthal, M. & Enerback, C. & 13 others, Krueger, G. G., Voorhees, J. J., Chandran, V., Rosen, C. F., Rahman, P., Gladman, D. D., Reis, A., Nair, R. P., Franke, A., Barker, J. N. W. N., Abecasis, G. R., Trembath, R. C. & Elder, J. T., 5/05/2015, In: Nature Communications. 6, 8 p., 7001.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

Schizophrenia Working Group of the Psychiatric Genomics Consortium, 03/2015, In: Nature Genetics. 47, 3, p. 291-295 5 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review