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Dr Leonie Unterholzner

Senior Lecturer in Molecular Immunology

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  1. Published

    DNA sensing in cancer: Pro-tumour and anti-tumour functions of cGAS-STING signalling

    Wheeler, O. P. G. & Unterholzner, L., 28/09/2023, In: Essays in Biochemistry. 67, 6, p. 905-918 14 p.

    Research output: Contribution to Journal/Magazine › Review article › peer-review

  2. Published

    Disparate STING signalling as a link between bladder cancer cell innate immune response and the immunostimulatory state of the tumour microenvironment following genotoxic therapies

    Walker, T., Morris, J. & Unterholzner, L., 17/04/2024.

    Research output: Contribution to conference - Without ISBN/ISSN › Poster

  3. Published

    Disparate STING signalling as a link between bladder cancer cell innate immune response and the immunostimulatory state of the tumour microenvironment following genotoxic therapies

    Walker, T. & Unterholzner, L., 7/05/2024.

    Research output: Contribution to conference - Without ISBN/ISSN › Poster

  4. Published

    Transcription stress causes an inflammatory response via release of IL-1α

    Walker, T. D. J., Morris, J. P. & Unterholzner, L., 30/04/2025, In: Nature Structural and Molecular Biology. 32, 4, p. 591-594 4 p., 14756.

    Research output: Contribution to Journal/Magazine › Journal article

  5. Published

    The interferon response to intracellular DNA: why so many receptors?

    Unterholzner, L., 11/2013, In: Immunobiology. 218, 11, p. 1312-1321 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  6. Published

    Vaccinia virus protein C6 is a virulence factor that binds TBK-1 adaptor proteins and inhibits activation of IRF3 and IRF7

    Unterholzner, L., Sumner, R. P., Baran, M., Ren, H., Mansur, D. S., Bourke, N. M., Randow, F., Smith, G. L. & Bowie, A. G., 09/2011, In: PLoS Pathogens. 7, 9, e1002247.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  7. Published

    Innate DNA sensing moves to the nucleus

    Unterholzner, L. & Bowie, A. G., 19/05/2011, In: Cell Host and Microbe. 9, 5, p. 351-353 3 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  8. Published

    IFI16 is an innate immune sensor for intracellular DNA

    Unterholzner, L., Keating, S. E., Baran, M., Horan, K. A., Jensen, S. B., Sharma, S., Sirois, C. M., Jin, T., Latz, E., Xiao, T. S., Fitzgerald, K. A., Paludan, S. R. & Bowie, A. G., 11/2010, In: Nature Immunology. 11, 11, p. 997-1004 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  9. Published

    The interplay between viruses and innate immune signaling: recent insights and therapeutic opportunities

    Unterholzner, L. & Bowie, A. G., 1/02/2008, In: Biochemical Pharmacology. 75, 3, p. 589-602 14 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  10. Published

    SMG7 acts as a molecular link between mRNA surveillance and mRNA decay

    Unterholzner, L. & Izaurralde, E., 19/11/2004, In: Molecular Cell. 16, 4, p. 587-596 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

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