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Research

Dr Leonie Unterholzner

Senior Lecturer in Molecular Immunology

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  1. 2024
  2. Published

    Single-stranded DNA oligonucleotides containing CpG motifs are non-stimulatory in vitro but offer protection in vivo against Burkholderia pseudomallei

    Scott, A., Farrar, B., Young, T., Prior, J., Stratilo, C., Unterholzner, L. & D’Elia, R., 18/10/2024, In: Frontiers in cellular and infection microbiology. 14, 1458435.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  3. Published

    Disparate STING signalling as a link between bladder cancer cell innate immune response and the immunostimulatory state of the tumour microenvironment following genotoxic therapies

    Walker, T. & Unterholzner, L., 7/05/2024.

    Research output: Contribution to conference - Without ISBN/ISSN › Poster

  4. Published

    Disparate STING signalling as a link between bladder cancer cell innate immune response and the immunostimulatory state of the tumour microenvironment following genotoxic therapies

    Walker, T., Morris, J. & Unterholzner, L., 17/04/2024.

    Research output: Contribution to conference - Without ISBN/ISSN › Poster

  5. 2023
  6. Published

    DNA sensing in cancer: Pro-tumour and anti-tumour functions of cGAS-STING signalling

    Wheeler, O. P. G. & Unterholzner, L., 28/09/2023, In: Essays in Biochemistry. 67, 6, p. 905-918 14 p.

    Research output: Contribution to Journal/Magazine › Review article › peer-review

  7. Published

    Innate immune sensing by cGAS-STING in animals reveals unexpected messengers

    Unterholzner, L., 20/07/2023, In: Cell. 186, 15, p. 3145-3147 3 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  8. 2022
  9. Published

    Myeloid cell nuclear differentiation antigen controls the pathogen-stimulated type I interferon cascade in human monocytes by transcriptional regulation of IRF7

    Gu, L., Casserly, D., Brady, G., Carpenter, S., Bracken, A. P., Fitzgerald, K. A., Unterholzner, L. & Bowie, A. G., 10/01/2022, In: Nature Communications. 13, 1, 14 p., 14.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  10. 2021
  11. Published

    Structural and Evolutionary Insights Into the Binding of Host Receptors by the Rabies Virus Glycoprotein

    Khalifa, M. E., Unterholzner, L. & Munir, M., 11/10/2021, In: Frontiers in cellular and infection microbiology. 11, 13 p., 736114.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  12. Published

    Structural mechanism of DNA recognition by the p204 HIN domain

    Fan, X., Jiang, J., Zhao, D., Chen, F., Ma, H., Smith, P., Unterholzner, L., Xiao, T. S. & Jin, T., 18/03/2021, In: Nucleic Acids Research. 49, 5, p. 2959-2972 14 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  13. 2019
  14. Published

    cGAS-independent STING activation in response to DNA damage

    Unterholzner, L. & Dunphy, G., 19/04/2019, In: Molecular & Cellular Oncology. 6, 4, 3 p., e1558682 .

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  15. Published

    Beyond sensing DNA: A role for cGAS in the detection of extracellular cyclic di-nucleotides

    Unterholzner, L., 1/04/2019, In: EMBO Reports. 20, 4, e47970.

    Research output: Contribution to Journal/Magazine › Journal article

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