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Professor Mick Urbaniak

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  1. Published

    Galactose starvation in a bloodstream form Trypanosoma brucei UDP-glucose 4'-epimerase conditional null mutant

    Urbaniak, M. D., Turnock, D. C. & Ferguson, M. A. J., 11/2006, In: Eukaryotic Cell. 5, 11, p. 1906-1913 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  2. Published

    Genetic and structural validation of Aspergillus fumigatus UDP-N-acetylglucosamine pyrophosphorylase as a potential antifungal target

    Fang, W., Du, T., Raimi, O. G., Hurtado-Guerrero, R., Urbaniak, M., Ibrahim, A. F. M., Ferguson, M. A. J. & van Aalten, D. M. F., 08/2013, In: Molecular Microbiology. 89, 3, p. 479-493 15 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  3. Published

    Genomic and Proteomic Studies on the mode of action of Oxaboroles against the African Trypanosome

    Jones, D. C., Foth, B. J., Urbaniak, M. D., Patterson, S., Ong, H. B., Berriman, M. & Fairlamb, A. H., 18/12/2015, In: PLoS Neglected Tropical Diseases. 9, 12, 18 p., e0004299.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  4. Published

    Global quantitative SILAC phosphoproteomics reveals differential phosphorylation is widespread between the procyclic and bloodstream form lifecycle stages of Trypanosoma brucei

    Urbaniak, M., Ferguson, M. A. J. & Martin, D. M. A., 14/03/2013, In: Journal of Proteome Research. 12, p. 2233-2244 12 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  5. Published

    High-confidence glycosome proteome for procyclic form Trypanosoma brucei by epitope-tag organelle enrichment and SILAC proteomics

    Güther, M. L. S., Urbaniak, M. D., Tavendale, A., Prescott, A. & Ferguson, M. A. J., 2014, In: Journal of Proteome Research. 13, 6, p. 2796-2806 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  6. Published

    Identification of novel inhibitors of UDP-Glc 4'-epimerase, a validated drug target for african sleeping sickness

    Urbaniak, M. D., Tabudravu, J. N., Msaki, A., Matera, K. M., Brenk, R., Jaspars, M. & Ferguson, M. A. J., 15/11/2006, In: Bioorganic and Medicinal Chemistry Letters. 16, 22, p. 5744-5747 4 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  7. Published

    Inhibitors incorporating zinc-binding groups target the GlcNAc-PI de-N-acetylase in Trypanosoma brucei, the causative agent of African sleeping sickness

    Abdelwahab, N. Z., Crossman, A. T., Sullivan, L., Ferguson, M. A. J. & Urbaniak, M., 03/2012, In: Chemical Biology and Drug Design. 79, 3, p. 270-278 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  8. Published

    LGAAP: Leishmaniinae Genome Assembly and Annotation Pipeline

    Almutairi, H., Urbaniak, M. D., Bates, M. D., Jariyapan, N., Kwakye-Nuako, G., Thomaz-Soccol, V., Al-Salem, W. S., Dillon, R. J., Bates, P. A. & Gatherer, D., 22/07/2021, In: Microbiology Resource Announcements. 10, 29, 5 p., e0043921.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  9. Published

    Molecular control of irreversible bistability during trypanosome developmental commitment

    Domingo Sananes, M. R., Szoor, B., Ferguson, M. A. J., Urbaniak, M. & Matthews, K. R., 19/10/2015, In: Journal of Cell Biology. 211, 2, p. 455-468 14 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  10. Published

    Organising the cell cycle in the absence of transcriptional control: Dynamic phosphorylation co-ordinates the Trypanosoma brucei cell cycle post-transcriptionally

    Benz, C. & Urbaniak, M., 12/12/2019, In: PLoS Pathogens. 15, 12, 27 p., e1008129.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  11. Published

    Phosphoproteomic analysis of mammalian infective Trypanosoma brucei subjected to heat shock suggests atypical mechanisms for thermotolerance

    Ooi, C. P., Benz, C. & Urbaniak, M., 15/05/2020, In: Journal of Proteomics. 219, 9 p., 103735.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  12. Published

    Probing enzymes late in the trypanosomal glycosylphosphatidylinositol biosynthetic pathway with synthetic glycosylphosphatidylinositol analogues

    Urbaniak, M. D., Yashunsky, D. V., Crossman, A., Nikolaev, A. V. & Ferguson, M. A. J., 17/10/2008, In: ACS Chemical Biology. 3, 10, p. 625-634 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  13. Published

    Probing the substrate specificity of Trypanosoma brucei GlcNAc-PI de-N-acetylase with synthetic substrate analogues

    Capes, A. S., Crossman, A., Urbaniak, M. D., Gilbert, S. H., Ferguson, M. A. J. & Gilbert, I. H., 2014, In: Organic and Biomolecular Chemistry . 2014, 12, p. 1919-1934 16 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  14. Published

    Probing Trypanosoma brucei glycosylphosphatidylinositol biosynthesis using novel precursor-analogues

    Urbaniak, M. D., Crossman, A. & Ferguson, M. A. J., 08/2008, In: Chemical Biology and Drug Design. 72, 2, p. 127-132 6 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  15. Published

    Protein-small molecule interactions in neocarzinostatin, the prototypical enediyne chromoprotein antibiotic

    Baker, J. R., Woolfson, D. N., Muskett, F. W., Stoneman, R. G., Urbaniak, M. D. & Caddick, S., 7/05/2007, In: ChemBioChem. 8, 7, p. 704-717 14 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  16. Published

    Proteome-wide quantitative phosphoproteomic analysis of Trypanosoma brucei insect and mammalian lifecycle stages

    Benz, C. & Urbaniak, M., 30/03/2020, Trypanosomatids: Methods and Protocols. Michels, P. A. M., Ginger, M. L. & Zilberstein, D. (eds.). New York: Humana Press, p. 125-137 13 p. (Methods in Molecular Biology ; vol. 2116).

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Chapter (peer-reviewed) › peer-review

  17. Published

    Re-evaluation of Diadenosine Tetraphosphate (Ap4A) From a Stress Metabolite to Bona Fide Secondary Messenger

    Ferguson, F., Sandy McLennan, P., Urbaniak, M., Nigel Jones, D. & Copeland, N., 17/11/2020, In: Frontiers in Molecular Biosciences. 7, 18 p., 606807.

    Research output: Contribution to Journal/Magazine › Book/Film/Article review › peer-review

  18. Published

    Solution structure of a novel chromoprotein derived from apo-neocarzinostatin and a synthetic chromophore

    Urbaniak, M. D., Muskett, F. W., Finucane, M. D., Caddick, S. & Woolfson, D. N., 1/10/2002, In: Biochemistry. 41, 39, p. 11731-11739 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  19. Published

    Synchronization of Trypanosoma brucei by Counter-Flow Centrifugal Elutriation

    Benz, C. & Urbaniak, M. D., 1/09/2022, Cell-Cycle Synchronization: Methods and Protocols. Wang, Z. (ed.). New York: Humana Press, p. 137-144 8 p. (Methods in Molecular Biology; vol. 2579).

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Chapter (peer-reviewed) › peer-review

  20. Published

    Synthesis of 1-D-6-O-[2-(N-hydroxyaminocarbonyl)amino-2-deoxy-alpha-D-glucopyranosyl]-myo-inositol 1-(n-octadecyl phosphate): a potential metalloenzyme inhibitor of glycosylphosphatidylinositol biosynthesis

    Crossman, A. T., Urbaniak, M. D. & Ferguson, M. A. J., 7/07/2008, In: Carbohydrate Research. 343, 9, p. 1478-1481 4 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  21. Published

    Synthesis of potential metal-binding group compounds to examine the zinc dependency of the GPI de-N-acetylase metalloenzyme in Trypanosoma brucei

    Abdelwahab, N. Z., Urbaniak, M. D., Ferguson, M. A. J. & Crossman, A. T., 1/05/2011, In: Carbohydrate Research. 346, 6, p. 708-714 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  22. Published

    The Dictyostelium prestalk inducer differentiation-inducing factor-1 (DIF-1) triggers unexpectedly complex global phosphorylation changes

    Sugden, C., Urbaniak, M. D., Araki, T. & Williams, J. G., 15/02/2015, In: Molecular Biology of the Cell. 26, 4, p. 805-820 16 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  23. Published

    The N-acetyl-D-glucosaminylphosphatidylinositol De-N-acetylase of glycosylphosphatidylinositol biosynthesis is a zinc metalloenzyme

    Urbaniak, M. D., Crossman, A., Chang, T., Smith, T. K., van Aalten, D. M. F. & Ferguson, M. A. J., 17/06/2005, In: Journal of Biological Chemistry. 280, 24, p. 22831-22838 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  24. Published

    TrypanoCyc: a community-led biochemical pathways database for Trypanosoma brucei

    Shameer, S., Logan-Klumpler, F. J., Vinson, F., Cottret, L., Merlet, B., Achcar, F., Boshart, M., Berriman, M., Breitling, R., Bringaud, F., Bütikofer, P., Cattanach, A. M., Bannerman-Chukualim, B., Creek, D. J., Crouch, K., de Koning, H. P., Denise, H., Ebikeme, C., Fairlamb, A. H., Ferguson, M. A. J., & 21 othersGinger, M. L., Hertz-Fowler, C., Kerkhoven, E. J., Mäser, P., Michels, P. A. M., Nayak, A., Nes, D. W., Nolan, D. P., Olsen, C., Silva-Franco, F., Smith, T. K., Taylor, M. C., Tielens, A. G. M., Urbaniak, M. D., van Hellemond, J. J., Vincent, I. M., Wilkinson, S. R., Wyllie, S., Opperdoes, F. R., Barrett, M. P. & Jourdan, F., 28/01/2015, In: Nucleic Acids Research. 43, D1, p. D637-D644 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  25. Published

    Trypanosoma brucei UDP-galactose-4'-epimerase in ternary complex with NAD+ and the substrate analogue UDP-4-deoxy-4-fluoro-alpha-D-galactose

    Alphey, M. S., Burton, A., Urbaniak, M. D., Boons, G-J., Ferguson, M. A. J. & Hunter, W. N., 1/09/2006, In: Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 62, 9, p. 829-834 6 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

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