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Research

Professor Mick Urbaniak

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  1. Published

    Inhibitors incorporating zinc-binding groups target the GlcNAc-PI de-N-acetylase in Trypanosoma brucei, the causative agent of African sleeping sickness

    Abdelwahab, N. Z., Crossman, A. T., Sullivan, L., Ferguson, M. A. J. & Urbaniak, M., 03/2012, In: Chemical Biology and Drug Design. 79, 3, p. 270-278 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  2. Published

    Synthesis of potential metal-binding group compounds to examine the zinc dependency of the GPI de-N-acetylase metalloenzyme in Trypanosoma brucei

    Abdelwahab, N. Z., Urbaniak, M. D., Ferguson, M. A. J. & Crossman, A. T., 1/05/2011, In: Carbohydrate Research. 346, 6, p. 708-714 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  3. Published

    Chromosome-Scale Assembly of the Complete Genome Sequence of Leishmania (Mundinia) martiniquensis, Isolate LSCM1, Strain LV760

    Almutairi, H., Urbaniak, M. D., Bates, M. D., Jariyapan, N., Al-Salem, W. S., Dillon, R. J., Bates, P. A. & Gatherer, D., 17/06/2021, In: Microbiology Resource Announcements. 10, 24, 3 p., e0005821.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  4. Published

    LGAAP: Leishmaniinae Genome Assembly and Annotation Pipeline

    Almutairi, H., Urbaniak, M. D., Bates, M. D., Jariyapan, N., Kwakye-Nuako, G., Thomaz-Soccol, V., Al-Salem, W. S., Dillon, R. J., Bates, P. A. & Gatherer, D., 22/07/2021, In: Microbiology Resource Announcements. 10, 29, 5 p., e0043921.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  5. Published

    Chromosome-scale genome sequencing, assembly and annotation of six genomes from subfamily Leishmaniinae

    Almutairi, H., Urbaniak, M. D., Bates, M. D., Jariyapan, N., Kwakye-Nuako, G., Thomaz Soccol, V., Al-Salem, W. S., Dillon, R. J., Bates, P. A. & Gatherer, D., 6/09/2021, In: Scientific Data. 8, 1, 9 p., 234.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  6. Published

    Chromosome-Scale Assembly of the Complete Genome Sequence of Leishmania (Mundinia) enriettii, Isolate CUR178, Strain LV763

    Almutairi, H., Urbaniak, M. D., Bates, M. D., Thomaz-Soccol, V., Al-Salem, W. S., Dillon, R. J., Bates, P. A. & Gatherer, D., 9/09/2021, In: Microbiology Resource Announcements. 10, 36, 3 p., e0057521.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  7. Published

    Chromosome-Scale Assembly of the Complete Genome Sequence of Leishmania (Mundinia) orientalis, Isolate LSCM4, Strain LV768

    Almutairi, H., Urbaniak, M. D., Bates, M. D., Jariyapan, N., Al-Salem, W. S., Dillon, R. J., Bates, P. A. & Gatherer, D., 9/09/2021, In: Microbiology Resource Announcements. 10, 36, 3 p., e0057421.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  8. Published

    Chromosome-Scale Assembly of the Complete Genome Sequence of Leishmania (Mundinia) sp. Ghana, Isolate GH5, Strain LV757

    Almutairi, H., Urbaniak, M. D., Bates, M. D., Kwakye-Nuako, G., Al-Salem, W. S., Dillon, R. J., Bates, P. A. & Gatherer, D., 30/09/2021, In: Microbiology Resource Announcements. 10, 39, 3 p., e0059121.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  9. Published

    Chromosome-Scale Assembly of the Complete Genome Sequence of Porcisia hertigi, Isolate C119, Strain LV43

    Almutairi, H., Urbaniak, M. D., Bates, M. D., Al-Salem, W. S., Dillon, R. J., Bates, P. A. & Gatherer, D., 14/10/2021, In: Microbiology Resource Announcements. 10, 41, 3 p., e0065121.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  10. Published

    Chromosome-Scale Assembly of the Complete Genome Sequence of Leishmania (Mundinia) procaviensis Isolate 253, Strain LV425

    Almutairi, H., Urbaniak, M. D., Bates, M. D., Kwakye-Nuako, G., Al-Salem, W. S., Dillon, R. J., Bates, P. A. & Gatherer, D., 18/04/2023, In: Microbiology Resource Announcements. 12, 4, 3 p., e0130622.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  11. Published

    Trypanosoma brucei UDP-galactose-4'-epimerase in ternary complex with NAD+ and the substrate analogue UDP-4-deoxy-4-fluoro-alpha-D-galactose

    Alphey, M. S., Burton, A., Urbaniak, M. D., Boons, G-J., Ferguson, M. A. J. & Hunter, W. N., 1/09/2006, In: Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 62, 9, p. 829-834 6 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  12. Published

    Protein-small molecule interactions in neocarzinostatin, the prototypical enediyne chromoprotein antibiotic

    Baker, J. R., Woolfson, D. N., Muskett, F. W., Stoneman, R. G., Urbaniak, M. D. & Caddick, S., 7/05/2007, In: ChemBioChem. 8, 7, p. 704-717 14 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  13. Published

    Cell cycle synchronisation of Trypanosoma brucei by centrifugal counter-flow elutriation reveals the timing of nuclear and kinetoplast DNA replication

    Benz, C., Dondelinger, F., McKean, P. G. & Urbaniak, M. D., 14/12/2017, In: Scientific Reports. 7, 10 p., 17599.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  14. Published

    Dynamic regulation of the Trypanosoma brucei transferrin receptor in response to iron starvation is mediated via the 3’UTR

    Benz, C., Lo, W., Fathallah, N., Connor-Guscott, A., Benns, H. J. & Urbaniak, M. D., 31/12/2018, In: PLoS ONE. 13, 12, 12 p., e0206332.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  15. Published

    Organising the cell cycle in the absence of transcriptional control: Dynamic phosphorylation co-ordinates the Trypanosoma brucei cell cycle post-transcriptionally

    Benz, C. & Urbaniak, M., 12/12/2019, In: PLoS Pathogens. 15, 12, 27 p., e1008129.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  16. Published

    Proteome-wide quantitative phosphoproteomic analysis of Trypanosoma brucei insect and mammalian lifecycle stages

    Benz, C. & Urbaniak, M., 30/03/2020, Trypanosomatids: Methods and Protocols. Michels, P. A. M., Ginger, M. L. & Zilberstein, D. (eds.). New York: Humana Press, p. 125-137 13 p. (Methods in Molecular Biology ; vol. 2116).

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Chapter (peer-reviewed) › peer-review

  17. Published

    Synchronization of Trypanosoma brucei by Counter-Flow Centrifugal Elutriation

    Benz, C. & Urbaniak, M. D., 1/09/2022, Cell-Cycle Synchronization: Methods and Protocols. Wang, Z. (ed.). New York: Humana Press, p. 137-144 8 p. (Methods in Molecular Biology; vol. 2579).

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Chapter (peer-reviewed) › peer-review

  18. Published

    Probing the substrate specificity of Trypanosoma brucei GlcNAc-PI de-N-acetylase with synthetic substrate analogues

    Capes, A. S., Crossman, A., Urbaniak, M. D., Gilbert, S. H., Ferguson, M. A. J. & Gilbert, I. H., 2014, In: Organic and Biomolecular Chemistry . 2014, 12, p. 1919-1934 16 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  19. Published

    Extensive Translational Regulation through the Proliferative Transition of Trypanosoma cruzi Revealed by Multi-Omics

    Chavez, S., Urbaniak, M., Benz, C., Smircich, P., Garat, B., Sotelo-Silveira, J. R. & Duhagon, M. A., 1/09/2021, In: mSphere. 6, 5, 21 p., e00366-21.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  20. Published

    Synthesis of 1-D-6-O-[2-(N-hydroxyaminocarbonyl)amino-2-deoxy-alpha-D-glucopyranosyl]-myo-inositol 1-(n-octadecyl phosphate): a potential metalloenzyme inhibitor of glycosylphosphatidylinositol biosynthesis

    Crossman, A. T., Urbaniak, M. D. & Ferguson, M. A. J., 7/07/2008, In: Carbohydrate Research. 343, 9, p. 1478-1481 4 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  21. Published

    Molecular control of irreversible bistability during trypanosome developmental commitment

    Domingo Sananes, M. R., Szoor, B., Ferguson, M. A. J., Urbaniak, M. & Matthews, K. R., 19/10/2015, In: Journal of Cell Biology. 211, 2, p. 455-468 14 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  22. Published

    Computer-aided identification of Trypanosoma brucei uridine diphosphate galactose 4'-epimerase inhibitors: toward the development of novel therapies for African sleeping sickness

    Durrant, J. D., Urbaniak, M. D., Ferguson, M. A. J. & McCammon, J. A., 8/07/2010, In: Journal of Medicinal Chemistry. 53, 13, p. 5025-5032 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  23. Published

    A multidimensional strategy to detect polypharmacological targets in the absence of structural and sequence homology

    Durrant, J. D., Amaro, R. E., Xie, L., Urbaniak, M. D., Ferguson, M. A. J., Haapalainen, A., Chen, Z., Di Guilmi, A. M., Wunder, F., Bourne, P. E. & McCammon, J. A., 22/01/2010, In: PLoS Computational Biology. 6, 1, 8 p., e1000648.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  24. Published

    Genetic and structural validation of Aspergillus fumigatus UDP-N-acetylglucosamine pyrophosphorylase as a potential antifungal target

    Fang, W., Du, T., Raimi, O. G., Hurtado-Guerrero, R., Urbaniak, M., Ibrahim, A. F. M., Ferguson, M. A. J. & van Aalten, D. M. F., 08/2013, In: Molecular Microbiology. 89, 3, p. 479-493 15 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  25. Published

    Re-evaluation of Diadenosine Tetraphosphate (Ap4A) From a Stress Metabolite to Bona Fide Secondary Messenger

    Ferguson, F., Sandy McLennan, P., Urbaniak, M., Nigel Jones, D. & Copeland, N., 17/11/2020, In: Frontiers in Molecular Biosciences. 7, 18 p., 606807.

    Research output: Contribution to Journal/Magazine › Book/Film/Article review › peer-review

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