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Research

Dr Panagiotis Kotsantis

Lecturer in Genome Stability and DNA Repair

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  1. 2024
  2. Published

    Evergene: an interactive webtool for large-scale gene-centric analysis of primary tumours

    Kennedy, A., Richardson, E., Higham, J., Kotsantis, P., Mort, R. & Shih, B. B.-J., 28/06/2024, In: Bioinformatics advances. 4, 1, vbae092.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  3. 2020
  4. Published

    RTEL1 Regulates G4/R-Loops to Avert Replication-Transcription Collisions

    Kotsantis, P., Segura-Bayona, S., Margalef, P., Marzec, P., Ruis, P., Hewitt, G., Bellelli, R., Patel, H., Goldstone, R., Poetsch, A. R. & Boulton, S. J., 22/12/2020, In: Cell Reports. 33, 12, 108546.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  5. 2019
  6. Published

    CDK phosphorylation of TRF2 controls t-loop dynamics during the cell cycle

    Sarek, G., Kotsantis, P., Ruis, P., Van Ly, D., Margalef, P., Borel, V., Zheng, X.-F., Flynn, H. R., Snijders, A. P., Chowdhury, D., Cesare, A. J. & Boulton, S. J., 21/11/2019, In: Nature. 575, p. 523-527 5 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  7. 2018
  8. Published

    Mechanisms of oncogene-induced replication stress: Jigsaw falling into place

    Kotsantis, P., Petermann, E. & Boulton, S. J., 30/04/2018, In: Cancer Discovery. 8, 5, p. 537-555 19 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  9. Published

    Stabilization of Reversed Replication Forks by Telomerase Drives Telomere Catastrophe

    Margalef, P., Kotsantis, P., Borel, V., Bellelli, R., Panier, S. & Boulton, S. J., 25/01/2018, In: Cell. 172, 3, p. 439-453 15 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  10. 2016
  11. Published

    Increased global transcription activity as a mechanism of replication stress in cancer

    Kotsantis, P., Silva, L. M., Irmscher, S., Jones, R. M., Folkes, L., Gromak, N. & Petermann, E., 11/10/2016, In: Nature Communications. 7, 13087.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  12. 2015
  13. Published

    Inference of protein kinetics by stochastic modeling and simulation of fluorescence recovery after photobleaching experiments

    Rapsomaniki, M. A., Cinquemani, E., Giakoumakis, N. N., Kotsantis, P., Lygeros, J. & Lygerou, Z., 28/02/2015, In: Bioinformatics. 31, 3, p. 355-362 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  14. Published

    Cancer Therapy and Replication Stress: Forks on the Road to Perdition

    Kotsantis, P., Jones, R. M., Higgs, M. R. & Petermann, E., 2015, Advances in Clinical Chemistry. Makowski, G. S. (ed.). Elsevier, p. 91-138 48 p. (Advances in Clinical Chemsitry; vol. 69).

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Chapter

  15. 2014
  16. Published

    BRCA2 and RAD51 promote double-strand break formation and cell death in response to gemcitabine

    Jones, R. M., Kotsantis, P., Stewart, G. S., Groth, P. & Petermann, E., 1/10/2014, In: Molecular Cancer Therapeutics. 13, 10, p. 2412-421 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  17. 2013
  18. Published

    Multi-step loading of human minichromosome maintenance proteins in live human cells

    Symeonidou, I.-E., Kotsantis, P., Roukos, V., Rapsomaniki, M.-A., Grecco, H. E., Bastiaens, P., Taraviras, S. & Lygerou, Z., 31/12/2013, In: Journal of Biological Chemistry. 288, 50, p. 35852-35867 16 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  19. Published

    ARF triggers senescence in Brca2-deficient cells by altering the spectrum of p53 transcriptional targets

    Carlos, A. R., Escandell, J. M., Kotsantis, P., Suwaki, N., Bouwman, P., Badie, S., Folio, C., Benitez, J., Gomez-Lopez, G., Pisano, D. G., Jonkers, J. & Tarsounas, M., 28/10/2013, In: Nature Communications. 4, 2697.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  20. Published

    Albumin upregulates eNOS mRNA through ETRA/B in human proximal tubular epithelial cells

    Kotsantis, P., Papadimitropoulos, A., Drakopoulos, A., Vlachojannis, J. G. & Katsoris, P., 2013, In: Journal of Nephrology.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  21. 2012
  22. Published

    EasyFRAP: An interactive, easy-to-use tool for qualitative and quantitative analysis of FRAP data

    Rapsomaniki, M. A., Kotsantis, P., Symeonidou, I.-E., Giakoumakis, N.-N., Taraviras, S. & Lygerou, Z., 31/07/2012, In: Bioinformatics. 28, 13, p. 1800-1801 2 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  23. Published

    Cdt1 is differentially targeted for degradation by anticancer chemotherapeutic drugs

    Stathopoulou, A., Roukos, V., Petropoulou, C., Kotsantis, P., Karantzelis, N., Nishitani, H., Lygerou, Z. & Taraviras, S., 30/03/2012, In: PLoS One. 7, 3, e34621.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  24. 2011
  25. Published

    Dynamic recruitment of licensing factor Cdt1 to sites of DNA damage

    Roukos, V., Kinkhabwala, A., Colombelli, J., Kotsantis, P., Taraviras, S., Nishitani, H., Stelzer, E., Bastiaens, P. & Lygerou, Z., 14/02/2011, In: Journal of Cell Science. 124, 3, p. 422-434 13 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  26. 2010
  27. Published

    Interaction of endothelin-1 and nitric oxide pathways in human tubular epithelial cells under the influence of cyclosporine-A

    Papachristou, E., Papadimitropoulos, A., Kotsantis, P., Goumenos, D. S., Katsoris, P. G. & Vlachojannis, J. G., 30/06/2010, In: Renal Failure. 32, 6, p. 727-732 6 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  28. 2009
  29. Published

    Cyclosporine induces endothelin-1 mRNA synthesis and nitric oxide production in human proximal tubular epithelial cell cultures

    Papachristou, E., Papadimitropoulos, A., Kotsantis, P., Goumenos, D. S., Katsoris, P. G. & Vlachojannis, J. G., 31/10/2009, In: Renal Failure. 31, 5, p. 372-376 5 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  30. 2008
  31. Published

    Elk-1 associates with FAK, regulates the expression of FAK and MAP kinases as well as apoptosis in HK-2 cells

    Mamali, I., Kotsantis, P., Lampropoulou, M. & Marmaras, V. J., 31/07/2008, In: Journal of Cellular Physiology. 216, 1, p. 198-206 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

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