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Dr Panagiotis Kotsantis

Lecturer in Genome Stability and DNA Repair

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  1. 2025
  2. E-pub ahead of print

    Human RNase H2 upregulation counteracts oncogene- and chemotherapy-induced replication stress

    Wilkins, R. J., Kannan, A., Plass, S. A., Wilson, C., Kelly, R. D. W., Tang, C. H. M., Kotsantis, P., Reijns, M. A. M., Kanhere, A. & Petermann, E., 10/07/2025, (E-pub ahead of print) In: Oncogene.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  3. 2024
  4. Published

    Evergene: an interactive webtool for large-scale gene-centric analysis of primary tumours

    Kennedy, A., Richardson, E., Higham, J., Kotsantis, P., Mort, R. & Shih, B. B.-J., 28/06/2024, In: Bioinformatics advances. 4, 1, vbae092.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  5. 2020
  6. Published

    RTEL1 Regulates G4/R-Loops to Avert Replication-Transcription Collisions

    Kotsantis, P., Segura-Bayona, S., Margalef, P., Marzec, P., Ruis, P., Hewitt, G., Bellelli, R., Patel, H., Goldstone, R., Poetsch, A. R. & Boulton, S. J., 22/12/2020, In: Cell Reports. 33, 12, 108546.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  7. 2019
  8. Published

    CDK phosphorylation of TRF2 controls t-loop dynamics during the cell cycle

    Sarek, G., Kotsantis, P., Ruis, P., Van Ly, D., Margalef, P., Borel, V., Zheng, X.-F., Flynn, H. R., Snijders, A. P., Chowdhury, D., Cesare, A. J. & Boulton, S. J., 21/11/2019, In: Nature. 575, p. 523-527 5 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  9. 2018
  10. Published

    Mechanisms of oncogene-induced replication stress: Jigsaw falling into place

    Kotsantis, P., Petermann, E. & Boulton, S. J., 30/04/2018, In: Cancer Discovery. 8, 5, p. 537-555 19 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  11. Published

    Stabilization of Reversed Replication Forks by Telomerase Drives Telomere Catastrophe

    Margalef, P., Kotsantis, P., Borel, V., Bellelli, R., Panier, S. & Boulton, S. J., 25/01/2018, In: Cell. 172, 3, p. 439-453 15 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  12. 2016
  13. Published

    Increased global transcription activity as a mechanism of replication stress in cancer

    Kotsantis, P., Silva, L. M., Irmscher, S., Jones, R. M., Folkes, L., Gromak, N. & Petermann, E., 11/10/2016, In: Nature Communications. 7, 13087.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  14. 2015
  15. Published

    Inference of protein kinetics by stochastic modeling and simulation of fluorescence recovery after photobleaching experiments

    Rapsomaniki, M. A., Cinquemani, E., Giakoumakis, N. N., Kotsantis, P., Lygeros, J. & Lygerou, Z., 28/02/2015, In: Bioinformatics. 31, 3, p. 355-362 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  16. Published

    Cancer Therapy and Replication Stress: Forks on the Road to Perdition

    Kotsantis, P., Jones, R. M., Higgs, M. R. & Petermann, E., 2015, Advances in Clinical Chemistry. Makowski, G. S. (ed.). Elsevier, p. 91-138 48 p. (Advances in Clinical Chemsitry; vol. 69).

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Chapter

  17. 2014
  18. Published

    BRCA2 and RAD51 promote double-strand break formation and cell death in response to gemcitabine

    Jones, R. M., Kotsantis, P., Stewart, G. S., Groth, P. & Petermann, E., 1/10/2014, In: Molecular Cancer Therapeutics. 13, 10, p. 2412-421 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

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