On the mechanisms of brain blood flow regulation during hypoxia

Mascarenhas, A., Braga, A., Majernikova, S. M., Nizari, S., Marletta, D., Theparambil, S. M., Aziz, Q., Marina, N. & Gourine, A. V., 15/04/2025, In: The Journal of Physiology. 603, 8, p. 2263-2280 18 p.

Research output: Contribution to Journal/Magazine › Review article › peer-review

Adenosine signalling to astrocytes coordinates brain metabolism and function

Theparambil, S. M., Kopach, O., Braga, A., Nizari, S., Hosford, P. S., Sagi-Kiss, V., Hadjihambi, A., Konstantinou, C., Esteras, N., Gutierrez Del Arroyo, A., Ackland, G. L., Teschemacher, A. G., Dale, N., Eckle, T., Andrikopoulos, P., Rusakov, D. A., Kasparov, S. & Gourine, A. V., 1/08/2024, In: Nature. 632, 8023, p. 139-146 8 p.

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pH regulating mechanisms of astrocytes: A critical component in physiology and disease of the brain

Theparambil, S. M., Begum, G. & Rose, C. R., 30/06/2024, In: Cell Calcium. 120, 102882.

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Astrocytes produce nitric oxide via nitrite reduction in mitochondria to regulate cerebral blood flow during brain hypoxia

Christie, I. N., Theparambil, S. M., Braga, A., Doronin, M., Hosford, P. S., Brazhe, A., Mascarenhas, A., Nizari, S., Hadjihambi, A., Wells, J. A., Hobbs, A., Semyanov, A., Abramov, A. Y., Angelova, P. R. & Gourine, A. V., 26/12/2023, In: Cell Reports. 42, 12, 113514.

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The astrocytic Na+-HCO3− cotransporter, NBCe1, is dispensable for respiratory chemosensitivity

Gourine, A. & Theparambil, S., 15/09/2023, In: The Journal of Physiology. p. 4171-4172 2 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Salt-loading promotes extracellular ATP release mediated by glial cells in the hypothalamic paraventricular nucleus of rats

Martins, S. R., Theparambil, S., Dos, S. K., Christie, I., Marina, N., Cardoso, B., Hosford, P. & Antunes, V., 31/03/2023, In: Molecular and cellular neurosciences. 124, 103806.

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CO2 signaling mediates neurovascular coupling in the cerebral cortex

Hosford, P., Wells, J., Nizari, S., Christie, I., Theparambil, S., Castro, P., Hadjihambi, A., Barros, L., Ruminot, I., Lythgoe, M. & Gourine, A., 19/04/2022, In: Nature Communications. 13, 2125.

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Glucagon-like peptide-1 (GLP-1) receptor activation dilates cerebral arterioles, increases cerebral blood flow, and mediates remote (pre)conditioning neuroprotection against ischaemic stroke

Nizari, S., Basalay, M., Chapman, P., Korte, N., Korsak, A., Christie, I. N., Theparambil, S., Davidson, S. M., Reimann, F., Trapp, S., Yellon, D. & Gourine, A., 3/05/2021, In: Basic research in cardiology. 116, 32.

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Mechanosensory Signaling in Astrocytes.

Turovsky, E., ALICE, B., Yu, Y., Esteras, N., Korsak, A., Theparambil, S., Hadjihambi, A., Hosford, P., Teschemacher, A., Marina, N., Lythgoe, M., Haydon, P. & Gourine, A., 2/12/2020, In: The Journal of neuroscience : the official journal of the Society for Neuroscience. 40, 49, p. 9364-9371

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Astrocytes regulate brain extracellular pH via a neuronal activity-dependent bicarbonate shuttle.

Theparambil, S., Hosford, P., Ruminot, I., Kopach, O., Reynolds, J., Sandoval, P. Y., Rusakov, D. A., Barros, L. & Gourine, A., 8/10/2020, In: Nature Communications. 11, 5073.

Research output: Contribution to Journal/Magazine › Journal article › peer-review